Zobrazeno 1 - 10
of 198
pro vyhledávání: '"W. Oettinger"'
Publikováno v:
AAPS PharmSciTech. 19:1908-1919
Targeted delivery to the lung for controlling lung inflammation is an area that we have explored in this study. The purpose was to use microparticles containing an antisense oligonucleotide (ASO) to NF-κB to inhibit the production of proinflammatory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f029c52c82b3633db24c74ed15be2d
https://doi.org/10.1208/s12249-018-1002-7
https://doi.org/10.1208/s12249-018-1002-7
Autor:
Martin J. D'Souza, Carl W. Oettinger
Publikováno v:
Journal of Microencapsulation
Context: This article reviews the use of albumin microcapsules 3–4 mm in size containing cytokine inhibiting drugs which include neutralizing antibodies to TNF and IL1, CNI-1493, antisense oligonucleotides to TNF and NF-kappaB, and the antioxidant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5951e2ca199b0403a49f0cfd821456f5
https://doi.org/10.3109/02652048.2012.658443
https://doi.org/10.3109/02652048.2012.658443
Autor:
Carl W. Oettinger, Rangaiah Shashidharamurthy, Martin J. D'Souza, Periasamy Selvaraj, Tuhin Bhowmik, Bernadette D’Souza
Publikováno v:
Journal of Drug Targeting. 20:166-173
Cancer vaccines are limited in their use, because of their inability to mount a robust anti-tumor immune response. Thus, targeting M-cells in the small intestine, which are responsible for entry of many pathogens, will be an attractive way to elicit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dffb5c5fc79c62e58acf53c9faf6b1f
https://doi.org/10.3109/1061186x.2011.622395
https://doi.org/10.3109/1061186x.2011.622395
Publikováno v:
European Journal of Chemistry. 2:125-129
Normal.dotm 0 0 1 124 709 Uni 5 1 870 12.0 0 false 18 pt 18 pt 0 0 false false false Polyethylene glycol 2000 (PEG) entrapped, bovine serum albumin (BSA) microspheres were prepared and optimized. These microspheres were then analyzed to understand th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e39fc00bd26a950b78f23d79d25933d6
https://doi.org/10.5155/eurjchem.2.2.125-129.394
https://doi.org/10.5155/eurjchem.2.2.125-129.394
Autor:
Rangaiah Shashidharamurthy, Periasamy Selvaraj, Bernadette D’Souza, Martin J. D'Souza, Carl W. Oettinger, Tuhin Bhowmik
Publikováno v:
Journal of Microencapsulation. 28:294-300
In this study, we formulated a microparticulate melanoma cancer vaccine via the transdermal route. The vaccine was delivered using microneedle-based Dermaroller® which is available for cosmetic purposes. Unlike subcutaneous injections, administratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::975c25ee61e4b40a3b31a1fb5544ad2c
https://doi.org/10.3109/02652048.2011.559287
https://doi.org/10.3109/02652048.2011.559287
Autor:
Janet Akande, Aladin Siddig, Richard T. Addo, Kwame G. Yeboah, Carl W. Oettinger, Martin J. D'Souza
Publikováno v:
Journal of Microencapsulation. 27:325-336
The purpose of this study was to evaluate the possibility of lectin-coupled microspheres to improve the targeted delivery of protein antigens to the lymphoid tissues of mucosal surfaces. Bovine serum albumin containing acid phosphatase model protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::099a08ced7ae79beaafd784b639d9eae
https://doi.org/10.3109/02652040903191834
https://doi.org/10.3109/02652040903191834
Autor:
Nishil Desai, Pawan K. Angra, Carl W. Oettinger, Henry Nettey, Martin J. D'Souza, Aladin Siddig
Publikováno v:
Journal of Microencapsulation. 26:627-634
The pharmacokinetics of Amphotericin B (AmB) from polyethylene glycol 2000 (PEG 2000) entrapped cross-linked bovine serum albumin (BSA) microsphere formulations were investigated and compared with solution formulation. The microsphere preparations we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7aeff88af92933ceea8884a545410586
https://doi.org/10.3109/02652040802587173
https://doi.org/10.3109/02652040802587173
Publikováno v:
Journal of Drug Targeting. 17:701-709
Microencapsulated (MC) catalase has been shown to inhibit H(2)O(2) and tumor necrosis factor (TNF) in vitro after endotoxin stimulation. It is the purpose of this study to determine whether MC catalase improves pro-inflammatory cytokine inhibition an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::831294b281fc4657f1e4099881997bef
https://doi.org/10.3109/10611860903062070
https://doi.org/10.3109/10611860903062070
Publikováno v:
Journal of Drug Targeting. :090804034138075-9
Reactive oxygen species synthesized by endothelial cells may be responsible for cell damage and altered physiologic function. After endotoxin stimulation, free radicals including H(2)O(2) are produced. We have developed a method of intracellular drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac57a7550a645670d672cdb1f8f3609a
https://doi.org/10.1080/10611860903161328
https://doi.org/10.1080/10611860903161328
Autor:
Carl W. Oettinger, Jamie C. Oliver
Publikováno v:
Artificial Organs. 13:432-437
It is generally agreed that bicarbonate dialysate is preferable to acetate dialysate, but the major limiting factors of high cost and technical difficulty in maintaining its stability for prolonged periods preclude its widespread use. The procedure d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::837185ff195c9266b1b03c1c76a93583
https://doi.org/10.1111/j.1525-1594.1989.tb01553.x
https://doi.org/10.1111/j.1525-1594.1989.tb01553.x