Zobrazeno 1 - 10
of 43
pro vyhledávání: '"W. N. Paul Lee"'
Autor:
Hernan Sierra, Reiko Sakurai, W. N. Paul Lee, Nghia C. Truong, John S. Torday, Virender K. Rehan
Publikováno v:
PPAR Research, Vol 2012 (2012)
Prenatally administered rosiglitazone (RGZ) is effective in enhancing lung maturity; however, its long-term safety remains unknown. This study aimed to determine the effects of prenatally administered RGZ on the metabolic phenotype of adult rats. Met
Externí odkaz:
https://doaj.org/article/d3574455a242400e862bfd4b20e47397
Autor:
Wei-lin Li, Vay Liang W. Go, Mary E. Patterson, W. N. Paul Lee, Paulin N. Wahjudi, Qing-Yi Lu, Xuemei Zhang, Jian Chen
Publikováno v:
Metabolomics. 13
Loquat leaf extract (LLE) is commonly used in China for a variety of ailments including diabetes. Several recent reports implicate LLE and a sesquiterpene glycoside, one of its components, as being an anti-hyperglycemic agent. However, the underlying
Autor:
Gary Guishan Xiao, Jing Huang, Xuemei Zhang, W. N. Paul Lee, Kevin Chen-Xiao, Vay Liang W. Go, Jianzhou Liu
Publikováno v:
Biomarker Research
Pancreatic cancer is characterized as a disease with low survival and high mortality because of no effective diagnostic and therapeutic strategies available in clinic. Conventional clinical diagnostic methods including serum markers and radiological
Publikováno v:
Clinical Biochemistry. 43:1269-1277
Tracer-based metabolomics is a systems biology tool that combines advances in tracer methodology for physiological studies, high throughput “-omics” technologies and constraint based modeling of metabolic networks. It is different from the common
Autor:
Paul M. Vespa, Daniel F. Kelly, Neil A. Martin, Joshua R. Dusick, Stefan M. Lee, Thomas C. Glenn, David A. Hovda, W N Paul Lee
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 27:1593-1602
Patients with traumatic brain injury (TBI) routinely exhibit cerebral glucose uptake in excess of that expected by the low levels of oxygen consumption and lactate production. This brings into question the metabolic fate of glucose. Prior studies hav
Publikováno v:
Metabolomics. 2:243-256
Understanding the metabolism of a cell requires knowledge about the intracellular biochemical structure as well as cellular responses to extracellular nutrients. Towards this goal, genomics and proteomics seek a complete description of the cell’s m
Dynamic profiling of the glucose metabolic network in fasted rat hepatocytes using [1,2-13C2]glucose
Autor:
Silvia Marin, Shu Lim, Josep J. Centelles, W. N. Paul Lee, Joan J. Guinovart, Sara Bassilian, Josep M. Fernández-Novell, Laszlo G. Boros, Marta Cascante
Publikováno v:
Biochemical Journal. 381:287-294
Recent studies in metabolic profiling have underscored the importance of the concept of a metabolic network of pathways with special functional characteristics that differ from those of simple reaction sequences. The characterization of metabolic fun
Autor:
W. N. Paul Lee, Sean B. Joseph, Irwin J. Kurland, Vicky Chang, Mohammed F. Saad, Chuck Trujillo, Sara Bassilian, Jun Xu
Publikováno v:
Endocrinology. 145:1087-1095
Our previous work led to the hypothesis that peroxisomal proliferator-activated receptor alpha (PPAR alpha) modulates insulin action in a compensatory fashion for hepatic glucose balance vs. peripheral glucose disposal. Therefore, we have examined th
Publikováno v:
Pancreatology. 16:S171-S172
Autor:
Jun Xu, Beau Chung, W. N. Paul Lee, Gary Xiao, Mohammed F. Saad, Felicia Hernandez, Sahar Makabi, Vicky Chang, Chuck Trujillo, Sara Bassilian, Sayed Ahmed, Lilia Blanco, Irwin J. Kurland
Publikováno v:
Analytical Biochemistry. 315:238-246
Increased glucose cycling between glucose and glucose-6-phosphate is characteristic of insulin resistance and hyperglycemia seen with Type II diabetes. Traditionally, glucose cycling is determined by the difference between hepatic glucose output meas