Zobrazeno 1 - 10
of 71
pro vyhledávání: '"W. Marie Campana"'
Autor:
W. Marie Campana, Steven L. Gonias
Publikováno v:
The American Journal of Pathology. 184(1):18-27
Low-density lipoprotein receptor-related protein-1 (LRP1) is an endocytic receptor for numerous proteins that are both structurally and functionally diverse. In some cell types, LRP1-mediated endocytosis is coupled to activation of cell signaling. LR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff730b1beb1805a56c4fed2386873c53
Autor:
Mingyong Gao, Daniel A. Lynam, W. Marie Campana, Jeff Sakamoto, Bridget Bednark, Mark H. Tuszynski, Paul Lu
Publikováno v:
Journal of neural engineering. 13(6)
Objective We combined implantation of multi-channel templated agarose scaffolds with growth factor gene delivery to examine whether this combinatorial treatment can enhance peripheral axonal regeneration through long sciatic nerve gaps. Approach 15 m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8048ab8912b2c852a3f37f5787a0d60
https://pubmed.ncbi.nlm.nih.gov/27762235
https://pubmed.ncbi.nlm.nih.gov/27762235
Autor:
Katerina Akassoglou, Alban Gaultier, Shinako Takimoto, Natacha Le Moan, Steven L. Gonias, Xiaohua Wu, Gatambwa Mukandala, W. Marie Campana
Publikováno v:
Journal of Cell Science. 122:1155-1162
Multiple sclerosis (MS) is an autoimmune disease in which myelin is progressively degraded. Because degraded myelin may both initiate and accelerate disease progression, clearing degraded myelin from extracellular spaces may be critical. In this stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27783fa288794c991e2d61751166933a
https://doi.org/10.1242/jcs.040717
https://doi.org/10.1242/jcs.040717
Autor:
Linda S. Sorkin, Camilla I. Svensson, W. Marie Campana, Michael P. Hefferan, Toni L. Jones-Cordero
Publikováno v:
Journal of Neuroscience Research. 87:948-955
Activation of p38 mitogen-activated protein kinase (MAPK) in the spinal cord has been implicated in the development and maintenance of pain states. In this study, we tested whether p38 MAPK is involved in the response to first-degree burn of the hind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc80e645769795268c0943e5df4c91cb
https://doi.org/10.1002/jnr.21905
https://doi.org/10.1002/jnr.21905
Autor:
Xiaoqing Li, Steven L. Gonias, W. Marie Campana, Gen Inoue, Kazuhisa Takahashi, Alban Gaultier, Elisabetta Mantuano
Publikováno v:
The Journal of Neuroscience. 28:11571-11582
Low-density lipoprotein receptor-related protein (LRP-1) is an endocytic receptor for diverse proteins, including matrix metalloproteinase-9 (MMP-9), and a cell-signaling receptor. In the peripheral nervous system (PNS), LRP-1 is robustly expressed b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fa2c78161b6547c746c82bc13c63b11
https://doi.org/10.1523/jneurosci.3053-08.2008
https://doi.org/10.1523/jneurosci.3053-08.2008
Publikováno v:
Journal of Biological Chemistry. 283:19904-19911
alpha(2)-Macroglobulin (alpha(2)M) is a plasma protease inhibitor, which reversibly binds growth factors and, in its activated form, binds to low density lipoprotein receptor-related protein (LRP-1), an endocytic receptor with cell signaling activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89d1f00b2ec7d0680ac76ea061d0eb90
https://doi.org/10.1074/jbc.m801762200
https://doi.org/10.1074/jbc.m801762200
Autor:
Steven L. Gonias, Alban Gaultier, Benjamin F. Cravatt, Sherry Niessen, Sanja Arandjelovic, Sergio Fazio, MacRae F. Linton, Cheryl D. Overton, W. Marie Campana
Publikováno v:
Blood. 111:5316-5325
Low-density lipoprotein receptor–related protein (LRP-1) functions in endocytosis and in cell signaling directly (by binding signaling adaptor proteins) or indirectly (by regulating levels of other cell-surface receptors). Because recent studies in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19275bce60f8d86b3460cab7bb4eb793
https://doi.org/10.1182/blood-2007-12-127613
https://doi.org/10.1182/blood-2007-12-127613
Autor:
Sanja Arandjelovic, Nikola Dragojlovic, Julie Janes, Xiaoqing Li, Alban Gaultier, Robert R. Myers, W. Marie Campana, Jenny Dolkas, George P. Zhou, Steven L. Gonias
Publikováno v:
Journal of Clinical Investigation. 118:161-172
Injury to the peripheral nervous system (PNS) initiates a response controlled by multiple extracellular mediators, many of which contribute to the development of neuropathic pain. Schwann cells in an injured nerve demonstrate increased expression of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aff93a4cff8ae89bd7153c0b92d2736
https://doi.org/10.1172/jci32371
https://doi.org/10.1172/jci32371
Autor:
Robert R. Myers, Nikola Dragojlovic, W. Marie Campana, Sanja Arandjelovic, Steven L. Gonias, Xiaoqing Li
Publikováno v:
Journal of Neurochemistry. 103:694-705
Peripheral nerve injury induces endoneural inflammation, controlled by diverse cytokines and extracellular mediators. Although inflammation is coupled to axonal regeneration, fulminant inflammation may increase nerve damage and neuropathic pain. alph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22e33b3e13b04bd9096bf09e7037b21e
https://doi.org/10.1111/j.1471-4159.2007.04800.x
https://doi.org/10.1111/j.1471-4159.2007.04800.x
Publikováno v:
Journal of cell science, vol 128, iss 18
NMDA receptors (NMDA-Rs) are ionotropic glutamate receptors, which associate with LDL-receptor-related protein-1 (LRP1) to trigger cell signaling in response to protein ligands in neurons. Here, we demonstrate for the first time that the NMDA-R is ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2544b0ab2cd1993692a2c20ad1b13885
https://pubmed.ncbi.nlm.nih.gov/26272917
https://pubmed.ncbi.nlm.nih.gov/26272917