Zobrazeno 1 - 10
of 60
pro vyhledávání: '"W. Macintyre"'
Autor:
Vincent Libis, Logan W. MacIntyre, Rabia Mehmood, Liliana Guerrero, Melinda A. Ternei, Niv Antonovsky, Ján Burian, Zongqiang Wang, Sean F. Brady
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Efficient mobilization and expression of biosynthetic gene clusters (BGCs) into heterologous hosts is needed for microbial natural products discovery. Here, the authors improve the CONKAT-seq strategy by simultaneously capturing the BCGs into a singl
Externí odkaz:
https://doaj.org/article/bf50f0e3f20d48b3a29e45a4676ef6ac
Autor:
Lei Li, Bimal Koirala, Yozen Hernandez, Logan W. MacIntyre, Melinda A. Ternei, Riccardo Russo, Sean F. Brady
Publikováno v:
Nature Microbiology. 7:120-131
The emergence of multidrug-resistant bacteria poses a threat to global health and necessitates the development of additional in vivo active antibiotics with diverse modes of action. Directly targeting menaquinone (MK), which plays an important role i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2aca9521bd6665f8b1a5d8fbd7ed351
https://doi.org/10.1038/s41564-021-01013-8
https://doi.org/10.1038/s41564-021-01013-8
Autor:
Lei Li, Riccardo Russo, Bimal Koirala, Thahmina Ali, Yozen Hernandez, Logan W MacIntyre, Sean F. Brady
Publikováno v:
Journal of Natural Products
Tuberculosis (TB) remains one of the deadliest infectious diseases. Unfortunately, the development of antibiotic resistance threatens our current therapeutic arsenal, which has necessitated the discovery and development of novel antibiotics against d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66f41646b74dc889dde6e9b3c7aec94b
http://europepmc.org/articles/PMC8068612
http://europepmc.org/articles/PMC8068612
Publikováno v:
Organic Letters. 21:7768-7771
The ichip (isolation chip) was employed for the first time in a marine sponge (Xestospongia muta), and a putatively new bacterial species, Alteromonas sp. RKMC-009, was isolated. Strain RKMC-009 produces a novel N-acyltyrosine (1) that is appended wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53b8e2a075cd619a4ced86ebaf423ae7
https://doi.org/10.1021/acs.orglett.9b02710
https://doi.org/10.1021/acs.orglett.9b02710
Autor:
Leah G. Bennett, David L. Jakeman, Hebelin Correa, Kerry B. Goralski, Jeanna M. MacLeod, Steven R. Hall, Russell G. Kerr, Stephanie M. Forget, Andrew W. Robertson, Logan W. MacIntyre
Publikováno v:
The Journal of Organic Chemistry. 83:1876-1890
Polyketide synthase (PKS) derived natural products are biosynthesized by head-to-tail addition of acetate and malonate extender units resulting in linear extended-polyketide chains. Despite the well-documented structural diversity associated with PKS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c34673c611f63401b2a7fb5cfe55e86a
https://doi.org/10.1021/acs.joc.7b02823
https://doi.org/10.1021/acs.joc.7b02823
Autor:
Logan W, MacIntyre, Marie J, Charles, Bradley A, Haltli, Douglas H, Marchbank, Russell G, Kerr
Publikováno v:
Organic letters. 21(19)
The ichip (isolation chip) was employed for the first time in a marine sponge (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e8e3e6eb0cbfda28065ed6f823466e67
https://pubmed.ncbi.nlm.nih.gov/31524403
https://pubmed.ncbi.nlm.nih.gov/31524403
Publikováno v:
Microbiology Resource Announcements
We report the draft whole-genome sequence of Alteromonas sp. strain RKMC-009, which was isolated in situ from the sponge Xestospongia muta in San Salvador, The Bahamas, using an isolation chip (ichip). Automated biosynthetic gene cluster analysis usi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e0788fcd39e6c07bf4b595282ef1442f
https://pubmed.ncbi.nlm.nih.gov/31221650
https://pubmed.ncbi.nlm.nih.gov/31221650
Publikováno v:
Journal of natural products. 81(12)
A new cyclic lipodepsipeptide, fusaristatin C (1), was obtained from the fungus Pithomyces sp. RKDO 1698, which was isolated from the Caribbean octocoral Eunicea fusca. The 2D structure of fusaristatin C was elucidated using NMR spectroscopy and mass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa612a871e8d0f9c5eb2fb962605a298
https://pubmed.ncbi.nlm.nih.gov/30525612
https://pubmed.ncbi.nlm.nih.gov/30525612
Autor:
Mary Ann Ryan, Sergei S. Likhodii, Stephen C. Cunnane, Kathy Musa, Cynthia A. Dell, W. MacIntyre Burnham
Publikováno v:
Lipids. 36:373-378
High-fat ketogenic diets are used to treat intractable seizures in children, but little is known of the mechanism by which these diets work or whether fats rich in n-3 polyunsaturates might be beneficial. Tissue lipid and fatty acid profiles were det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cb77493f58a9f3fcda48f182bebdc10
https://doi.org/10.1007/s11745-001-0730-8
https://doi.org/10.1007/s11745-001-0730-8
Publikováno v:
Neuroscience. 94:1083-1095
How seizures arise and recur in epilepsy is unknown. Recent genetic, pharmacological and electrophysiological data indicate a significant but undisclosed role for voltage-dependent calcium channels. Since the contribution such channels make to nerve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee2651b2a8ffa23db2428a459b877f34
https://doi.org/10.1016/s0306-4522(99)00371-1
https://doi.org/10.1016/s0306-4522(99)00371-1