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Publikováno v:
International Journal of Pharmaceutics. 280:173-183
Intravascular devices are widely used for vascular access but are associated with substantial risk of development of devices-related bloodstream infection (DR-BSI), which causes a considerable increase of morbidity and mortality, prolonged hospitalis
Publikováno v:
Scopus-Elsevier
In order to improve the resistance of catheters to microbial infections (particularly Staphylococci), a cephalosporin type antibiotic (cefamandole, CEF), and a glycopeptidic antibiotic (vancomycin), were adsorbed onto functionalized polyurethane film
Publikováno v:
Journal of Molecular Catalysis B: Enzymatic. 15:93-99
In order to evaluate the influence of the immobilization techniques of fumarase on its immobilization yield and on its catalytic activity, it was covalently bonded to the surface of polymers (consisting of suitably functionalized ethylene–vinyl alc
Publikováno v:
Journal of Bioactive and Compatible Polymers. 16:294-306
In order to obtain antimicrobial polymer compositions potentially suitable for catheter fabrication, a cephalosporin was bonded to ethylene-vinyl alcohol copolymers and to their derivatives containing hydrophilic positively or negatively charged grou
Publikováno v:
European Polymer Journal. 37:1021-1025
In order to obtain polymers provided with improved haemocompatibility a commercial ethylene-vinyl alcohol copolymer (EVAL) was chemically modified by the introduction of different amounts of carboxylated groups. The carboxylation was carried out by r
Publikováno v:
Journal of Bioactive and Compatible Polymers. 15:257-271
To obtain polymers with improved hemocompatibility properties, commercial ethylene-vinyl alcohol copolymers (EVAL) were chemically modified, by the introduction of stearoyl groups to bind albumin and quaternary ammonium groups to bind heparin. These
Publikováno v:
Macromolecular Chemistry and Physics. 201:715-721
Full Paper: In order to obtain polymers provided with improved haemocompatibility a commercial ethylene-vinyl alcohol copolymer (EVAL) was chemically modified by introduction of different amounts of sulfate groups. The sulfation reaction was carried
Publikováno v:
Macromolecular Chemistry and Physics. 200:1191-1199
Hydrophobic terpolymers ethylene/vinyl alcohol/vinyl stearate, of three different compositions, have been obtained by reaction of a commercial ethylene/vinyl alcohol copolymer (EVAL) with stearoyl chloride at different molar ratios. The obtained poly
Publikováno v:
Biomaterials. 18:885-890
In order to prepare polymer surfaces of vinyl type, provided with long-term haemocompatibility, a commercial ethylene-vinyl alcohol copolymer (EVAL) was covalently heparinized, employing two different bifunctional reagents (adipoil chloride and hexam