Zobrazeno 1 - 10
of 112
pro vyhledávání: '"W. M. Selig"'
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 277(3)
Bradykinin B1 receptors have been identified in a limited number of human tissues and may have implications in pathological states of chronic inflammation. In the present study, longitudinal strips of postmortem human ileum displayed a strong contrac
Publikováno v:
American journal of respiratory and critical care medicine. 151(2 Pt 1)
The effect of bilateral vagal stimulation on aerosolized antigen-induced responses was examined in the sensitized, perfused guinea pig lung. Vagal stimulation in the sensitized, perfused lung resulted in bronchoconstriction (peak response 160 +/- 18%
Autor:
M, O'Donnell, R J, Garippa, N, Rinaldi, W M, Selig, B, Simko, L, Renzetti, S A, Tannu, M A, Wasserman, A, Welton, D R, Bolin
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 270(3)
Ro 25-1553, a cyclic peptide analog of vasoactive intestinal peptide (VIP), was designed to overcome many of the deficiencies inherent in this natural neuropeptide. On isolated guinea pig tracheal smooth muscle, Ro 25-1553 produces concentration-depe
Autor:
M, O'Donnell, R J, Garippa, N, Rinaldi, W M, Selig, J E, Tocker, S A, Tannu, M A, Wasserman, A, Welton, D R, Bolin
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 270(3)
Studies were conducted to compare the effect of native vasoactive intestinal peptide (VIP), Ro 25-1553 (a cyclic peptide analog of VIP) and salbutamol (a beta2-adrenoceptor agonist) on antigen-induced pathophysiological effects in the guinea pig. Ro
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 259(1)
Ro 24-4736, (5-(3-[4-(2-chlorophenyl)-9-methyl-6H-thieno[3,2-f] [1,2,4]triazolo[4,3-a][1,4]diazepin-2-yl]-2-propynyl)phenanthri din- 6(5H)-one), has been identified as a potent, selective, p.o.-active platelet-activating factor (PAF) antagonist with
Publikováno v:
American journal of respiratory cell and molecular biology. 4(4)
Antigen challenge of actively sensitized guinea pigs produces airway eosinophilia, airway hyperreactivity, and late-phase bronchoconstriction. The recruited eosinophils are thought to be important cells in the development of the airway hyperreactivit
Publikováno v:
The American review of respiratory disease. 142(5)
The effect of phospholipase A2 (Naja naja) PLA2) on mean arterial blood pressure and intratracheal pressure was examined in anesthetized guinea pigs. Intracheally administered PLA2 (1 to 10 U) produced acute, dose-dependent increases in mean arterial
Autor:
S K, Durham, W M, Selig
Publikováno v:
The American journal of pathology. 136(6)
The pathophysiology of lung injury induced by phospholipase A2 (PLA2), a lipolytic enzyme implicated in a variety of pulmonary diseases, was examined in the guinea pig. One hundred microliters of saline or 10 units of PLA2 suspended in saline was giv
Publikováno v:
Journal of Applied Physiology. 60:1980-1985
The effects of temperature (37–45 degrees C) on pulmonary edema formation and transendothelial albumin clearance were investigated using isolated perfused guinea pig lungs and bovine pulmonary arterial endothelial cells grown to confluency on a gel
Publikováno v:
American Review of Respiratory Disease. 136:134-141
We examined the alterations in pulmonary transvascular fluid and protein exchange after intravenous infusion of fat emboli, i.e., bone marrow suspension (BMS) in awake sheep prepared with chronic lung lymph fistulas and compared these changes with th