Zobrazeno 1 - 4
of 4
pro vyhledávání: '"W. M. Maniara"'
Publikováno v:
Biomedical Chromatography. 8:247-250
A quantitative analytical method for the determination of a new thromboxane synthetase inhibitor (CGS 22652) in human plasma has been developed using high performance liquid chromatography (HPLC). The drug and internal standard (CGS 23298) were extra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82b61d71be6940a03bdb2773bfde6174
https://doi.org/10.1002/bmc.1130080510
https://doi.org/10.1002/bmc.1130080510
Autor:
T D, Aicher, R C, Anderson, J, Gao, S S, Shetty, G M, Coppola, J L, Stanton, D C, Knorr, D M, Sperbeck, L J, Brand, C C, Vinluan, E L, Kaplan, C J, Dragland, H C, Tomaselli, A, Islam, R J, Lozito, X, Liu, W M, Maniara, W S, Fillers, D, DelGrande, R E, Walter, W R, Mann
Publikováno v:
Journal of medicinal chemistry. 43(2)
N'-methyl-N-(4-tert-butyl-1,2,5,6-tetrahydropyridine)thiourea, SDZ048-619 (1), is a modest inhibitor (IC(50) = 180 microM) of pyruvate dehydrogenase kinase (PDHK). In an optimization of the N-methylcarbothioamide moiety of 1, it was discovered that a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b1772832e8ae976302ee3c02cf1e34f5
https://pubmed.ncbi.nlm.nih.gov/10649979
https://pubmed.ncbi.nlm.nih.gov/10649979
Publikováno v:
Biomedical chromatography : BMC. 8(6)
A sensitive and specific analytical method has been developed for the determination of a new anxiolytic (CGS 19480A) in human plasma using high performance liquid chromatography (HPLC). The drug and internal standard (CGS 18102A), were extracted with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0c83fef8a9cf827698cad2471dd0de2
https://pubmed.ncbi.nlm.nih.gov/7888731
https://pubmed.ncbi.nlm.nih.gov/7888731
Publikováno v:
Advances in experimental medicine and biology. 283
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::59d6fbc3cd1035eced0c8440bd3f1dc1
https://pubmed.ncbi.nlm.nih.gov/2069029
https://pubmed.ncbi.nlm.nih.gov/2069029