Zobrazeno 1 - 5
of 5
pro vyhledávání: '"W. M. Macfarlane"'
Autor:
H, Pelling, L J, Bock, J, Nzakizwanayo, M E, Wand, E L, Denham, W M, MacFarlane, J M, Sutton, B V, Jones
Publikováno v:
Antimicrobial Agents and Chemotherapy
Proteus mirabilis is a common pathogen of the catheterized urinary tract and often described as intrinsically resistant to the biocide chlorhexidine (CHD). Here, we demonstrate that derepression of the smvA efflux system has occurred in clinical isol
Autor:
A, Aldibbiat, A, Alidibbiat, C E, Marriott, K T, Scougall, S C, Campbell, G C, Huang, W M, Macfarlane, J A M, Shaw
Publikováno v:
The Journal of endocrinology. 196(1)
Generation of new β-cells from the adult pancreas or the embryonic stem cells is being pursued by research groups worldwide. Success will be dependent on confirmation of true β-cell phenotype evidenced by capacity to process and store proinsulin. T
Autor:
W M Macfarlane
Publikováno v:
Molecular pathology : MP. 53(1)
The transcription of genes could be defined as the intricate molecular manoeuvres occurring in the nuclei of cells, which allow the translation of genetic information held in the DNA into the proteins required for life. Gene transcription is the domi
Autor:
Jennifer M. Tremble, J. P. Banga, Kathryn Haskins, John C. Hutton, K. Docherty, W. M. Macfarlane, Roger F.L. James, Timothy Tree, D. O’Byrne
SUMMARYType 1 diabetes is a T cell-mediated autoimmune disease where a number of islet β-cell target autoantigens have been characterized on the basis of reactivity with autoantibodies. Nevertheless, there remains uncertainty of the nature of anothe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6763e5cf693fbcd1d718ad7f76f3b921
https://europepmc.org/articles/PMC1905664/
https://europepmc.org/articles/PMC1905664/
Publikováno v:
Scopus-Elsevier
In the human insulin gene, three regulatory sequences upstream of the transcription start site at -77 (the CT1 box), -210 (the CT2 box), and -315 (the CT3 box) bind a beta-cell-specific transcription factor, IUF1. Recent studies have mapped a glucose