Zobrazeno 1 - 10
of 25
pro vyhledávání: '"W. M. Layton"'
Autor:
David M. Kurnit, Julia E. Richards, G. D. Stewart, W. M. Layton, Lucy B. Rowe, Benjamin A. Taylor, Mary Layton, Andrzej J. Hanzlik, Malgorzata M. Osemlak, Michael Binder
Publikováno v:
Genomics. 7:389-393
The iv gene controls left-right determination during murine organogenesis. To map this gene, we analyzed backcross progeny produced by mating (C57BL/6J X MEV/Ty)F1-iv/+heterozygotes to C57BL/6J-iv homozygotes. Hybridization of a murine ecotropic viru
Autor:
M. W. Layton, Fred G. Biddle, Margaret L. Van Keuren, Andrzej J. Hanzlik, W. M. Layton, Michael Binder, David M. Kurnit
Publikováno v:
Teratology. 47(6)
Approximately 50% of iuliu mice have situs incersus (mirror image reversal of viscera) and 40% have heterotaxia (anomalous arrangement of viscera). The occurrence of heterotaxia is independent of situs. Using the cross-intercross breeding system to p
Publikováno v:
Molecular reproduction and development. 29(2)
To decipher genes that are important in the determination of laterality, we compared two-dimensional protein gels from wild-type C57BL/6J mice and C57BL/6J mice that carried the iv mutation, which confers random determination of visceral situs. To sp
Autor:
Roger Ratcliff, W. M. Layton
Publikováno v:
Behavior Research Methods & Instrumentation. 13:216-220
A microcomputer system for real-time control of experiments in cognitive psychology is described. The microcomputer serves as an interface that allows a remote timesharing computer to control the timed display of textual material on CRTs and collect
Autor:
W. M. Layton, J. M. Smith
Publikováno v:
Teratology. 15:171-177
Craniomyeloschisis (proposed gene symbol cms) was a spontaneous mutation of the rat inherited as an autosomal recessive trait with complete penetrance. Homozygous offspring died at birth with failure of closure of the neural tube caudal to the midbra
Autor:
Vergil H. Ferm, W. M. Layton
Publikováno v:
Teratology. 21:357-360
Administration of 12 μmol/kg of cadmium sulfate ip to C57BL/6J mice within 3 weeks prior to pregnancy significantly reduced the incidence of limb malformations induced by 6 μrnol/kg of cadmium sulfate given ip on day 9 of pregnancy. In another expe
Autor:
W. M. Layton, D. W. Hallesy
Publikováno v:
Experimental Biology and Medicine. 126:6-8
SummaryAdministration of very high doses of dichlorphenamide, a carbonic anhydrase inhibitor, in the diet of rats during pregnancy is associated with the production, in some of the offspring, of a deformity consisting of a postaxial defect of the rig
Autor:
W. M. Layton, D. W. Hallesy
Publikováno v:
Science. 149:306-308
Publikováno v:
Journal of applied physiology: respiratory, environmental and exercise physiology. 48(5)
Intact rats exposed for 30 days to various levels of simulated altitude from 12,000 (3,658 m) to 20,000 ft (6,096 m) showed a sharp increase in circulating red blood cells in reticulocytes, and in spleen-to-body weight ratios above 15,000 ft (4.572 m
Autor:
Thomas F. Gale, W. M. Layton
Publikováno v:
Teratology. 21(2)
Prior research has involved several aspects of cadmium-induced embryotoxicity in non-inbred hamsters, mice, and rats. This study compares the embryotoxic profile of cadmium in one non-inbred (LVG) and five inbred (CB, LHC, LSH, MHA, PD4) strains of h