Zobrazeno 1 - 10
of 365
pro vyhledávání: '"W. M. Fan"'
Autor:
L. Y. Zhang, W. M. Fan, L. Ding, M. N. Ducea, A. Pullen, J. X. Li, Y. L. Sun, Y. H. Yue, F. L. Cai, C. Wang, T. P. Peng, Kyaing Sein
Publikováno v:
Geochemistry, Geophysics, Geosystems, Vol 21, Iss 8, Pp n/a-n/a (2020)
Abstract Magmatic processes that occur during the transition from oceanic to continental subduction and collision in orogens are critical and still poorly resolved. Oceanic slab detachment in particular is hypothesized to mark a fundamental change in
Externí odkaz:
https://doaj.org/article/5052c38f04f9452a855f62dd46af01e0
Autor:
W-M Fan, Teresa, Islam, Jahid M.M., Higashi, Richard M., Lin, Penghui, Brainson, Christine F., Lane, Andrew N.
Publikováno v:
In Journal of Biological Chemistry January 2024 300(1)
Publikováno v:
In Methods October 2022 206:8-17
Autor:
Rony Panarsky, Daniel R. Crooks, Andrew N. Lane, Youfeng Yang, Teresa A. Cassel, Teresa W.-M. Fan, W. Marston Linehan, Jeffrey A. Moscow
Publikováno v:
Cancer & Metabolism, Vol 8, Iss 1, Pp 1-15 (2020)
Abstract Background The loss-of-function mutation of fumarate hydratase (FH) is a driver of hereditary leiomyomatosis and renal cell carcinoma (HLRCC). Fumarate accumulation results in activation of stress-related mechanisms leading to upregulation o
Externí odkaz:
https://doaj.org/article/0dceb078fdad4b62bc2e715b95444bdb
Publikováno v:
Genes and Diseases, Vol 7, Iss 2, Pp 185-198 (2020)
The genetic alterations associated with cell transformation are in large measure expressed in the metabolic phenotype as cancer cells proliferate and change their local environment, and prepare for metastasis. Qualitatively, the fundamental biochemis
Externí odkaz:
https://doaj.org/article/b1e19b835a9e4ed394d02f9b006c0494
Autor:
Dipanwita Sengupta, Teresa Cassel, Kun-yu Teng, Mona Aljuhani, Vivek K. Chowdhary, Peng Hu, Xiaoli Zhang, Teresa W.-M. Fan, Kalpana Ghoshal
Publikováno v:
Molecular Metabolism, Vol 34, Iss , Pp 174-186 (2020)
Objective: It is well established that the liver-specific miR-122, a bona fide tumor suppressor, plays a critical role in lipid homeostasis. However, its role, if any, in amino acid metabolism has not been explored. Since glutamine (Gln) is a critica
Externí odkaz:
https://doaj.org/article/e94018977b7a47ee8dc02a6ee0c626c7
Autor:
Erika M. Palmieri, Marieli Gonzalez-Cotto, Walter A. Baseler, Luke C. Davies, Bart Ghesquière, Nunziata Maio, Christopher M. Rice, Tracey A. Rouault, Teresa Cassel, Richard M. Higashi, Andrew N. Lane, Teresa W.-M. Fan, David A. Wink, Daniel W. McVicar
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Production of inflammatory mediators by M1-polarized macrophages is thought to rely on suppression of mitochondrial metabolism in favor of glycolysis. Refining this concept, here the authors define metabolic targets of nitric oxide as responsible for
Externí odkaz:
https://doaj.org/article/1aabd0cb2c6e480fa1e6ac1eb3b1dd56
Publikováno v:
eLife, Vol 10 (2021)
Cellular metabolism has key roles in T cells differentiation and function. CD4+ T helper-1 (Th1), Th2, and Th17 subsets are highly glycolytic while regulatory T cells (Tregs) use glucose during expansion but rely on fatty acid oxidation for function.
Externí odkaz:
https://doaj.org/article/851c6bd2a26549a4b642403b49029a4d
Autor:
Timothy L. Scott, Juan Zhu, Teresa A. Cassel, Sara Vicente-Muñoz, Penghui Lin, Richard M. Higashi, Andrew N. Lane, Teresa W.-M. Fan
Publikováno v:
Metabolites, Vol 12, Iss 8, p 760 (2022)
Glycogen is a readily deployed intracellular energy storage macromolecule composed of branched chains of glucose anchored to the protein glycogenin. Although glycogen primarily occurs in the liver and muscle, it is found in most tissues, and its meta
Externí odkaz:
https://doaj.org/article/130af625bf0240b28d4779f4a79268fe
Autor:
Saeed Daneshmandi, Teresa Cassel, Penghui Lin, Richard M. Higashi, Gerburg M. Wulf, Vassiliki A. Boussiotis, Teresa W.-M. Fan, Pankaj Seth
Publikováno v:
Cell Reports, Vol 34, Iss 10, Pp 108831- (2021)
Summary: Although T cell expansion depends on glycolysis, T effector cell differentiation requires signaling via the production of reactive oxygen species (ROS). Because the pentose phosphate pathway (PPP) regulates ROS by generating nicotinamide ade
Externí odkaz:
https://doaj.org/article/acce3d944b2e4a188f1edec534596d20