Zobrazeno 1 - 10 of 17 pro vyhledávání: '"W. M. A. Niessen"'
1
Identification of very long-chain (C
Autor: B, Garlito, T, Portolés, W M A, Niessen, J C, Navarro, F, Hontoria, Ó, Monroig, I, Varó, R, Serrano
Publikováno v: Analytica chimica acta. 1051
Gas chromatography coupled to a quadrupole time-of-flight mass analyzer (QTOF) with an atmospheric pressure chemical ionization (APCI) source has been tested to study the ionization and mass spectrometric behavior of long-chain and very long-chain po
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::7e317a8c21179a4a3704a16776437635
https://pubmed.ncbi.nlm.nih.gov/30661606
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2
Cationization Mass Spectrometry for Condensed-Phase Samples
Autor: W. M. A. Niessen
Publikováno v: Ion/Molecule Attachment Reactions: Mass Spectrometry ISBN: 9781489975874
Chapter 7 Electron ionization (EI) is the gold standard in analyte ionization by mass spectrometry (MS). As an alternative to EI, a wide variety of alternative ionization techniques have been developed. A characteristic feature of these ionization te
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::344489f966453adf33b48b79d23c13b1
https://doi.org/10.1007/978-1-4899-7588-1_7
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3
Summary and Perspectives
Autor: W. M. A. Niessen
Publikováno v: Ion/Molecule Attachment Reactions: Mass Spectrometry ISBN: 9781489975874
Chapter 9 Alkali+-cationization in ion-attachment mass spectrometry (IAMS) is an important tool for analyte ionization, next to more conventional approaches like electron ionization and protonation by soft-ionization techniques like electrospray ioni
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d3ab28e87d71c3a966af925f1b42a582
https://doi.org/10.1007/978-1-4899-7588-1_9
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5
Investigating the presence of omeprazole in waters by liquid chromatography coupled to low and high resolution mass spectrometry: degradation experiments
Autor: C, Boix, M, Ibáñez, J V, Sancho, W M A, Niessen, F, Hernández
Publikováno v: Journal of mass spectrometry : JMS. 48(10)
Omeprazole is one of the most consumed pharmaceuticals around the world. However, this compound is scarcely detected in urban wastewater and surface water. The absence of this pharmaceutical in the aquatic ecosystem might be due to its degradation in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::65dfd36cb482c7779aa2651c1098d175
https://pubmed.ncbi.nlm.nih.gov/24130012
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6
Tandem mass spectrometry study of p38α kinase inhibitors and related substances
Autor: D, Falck, J, Kool, M, Honing, W M A, Niessen
Publikováno v: Journal of mass spectrometry : JMS. 48(6)
The p38 mitogen-activated protein kinase α (p38α) is an important drug target widely investigated for therapy of chronic inflammatory diseases. Its inhibitors are rather lipophilic and as such not very favourable lead compounds in drug discovery. T
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e9f324aecd443fe0583b8a7cc87ac5a7
https://pubmed.ncbi.nlm.nih.gov/23722963
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7
High-resolution metabolic profiling towards G protein-coupled receptors: rapid and comprehensive screening of histamine H₄ receptor ligands
Autor: J, Kool, A F, Rudebeck, F, Fleurbaaij, S, Nijmeijer, D, Falck, R A, Smits, H F, Vischer, R, Leurs, W M A, Niessen
Publikováno v: Journal of chromatography. A. 1259
In the past years we developed high-resolution screening platforms involving separation of bioactive mixtures and on-line or at-line bioassays for a wide variety of biological targets with parallel mass spectrometric detection and identification. In
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::08da755be03ce034397ad390eddffe12
https://pubmed.ncbi.nlm.nih.gov/22520160
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8
Abstracts of lectures and posters pharmaceutical and biomedical analysis meeting
Autor: Erik Endert, J. van der Greef, E. H. M. Koster, A. T. Van Oosterom, F. A. Maris, F. Berends, F. J. Bruggeman, S. Copinga, J. Teeuwsen, I. Ouintens, Zhu Yongxin, P. M. J. van Santvoort, Peter L. Jacobs, Antje Klockow, M. J. M. van Zeeland, Aran Paulus, R. J. M. Vervoort, Jos H. Beijnen, J. L. E. Reubsaet, M. W. J. Derksen, H. Irth, C. Hendrix, R. Busson, K. Wouters, Herman A. H. Rongen, H. Kerkdijk, C. Opper, Philippe Mussche, Wout P. van Bennekom, U. R. Tjaden, Eric de Witte, A. J. Oosterkamp, W. M. A. Niessen, C. J. Verstappen, I. J. Bosman, Jp Franke, E. A. De Bruijn, J. C. M. Waterval, G. Thoithi, Ch. M. J. de Pooter, Norbert Lammers, J. Paesen, M. H. Simonian, Frans Biermans, A. Van Schepdael, Auke Bult, P. Claeys, K. Ensing, W. Pluijms, A. Solie, P. G. Scalliet, Marcel P. de Vries, I. Dekker, Jos Hoogmartens, W. Cypers, A. Bult, J. Šmisterová, P. Herdewijn, R. A. Maes, Gerard J. M. Bruin, D. E. M. M. Vendrig, A. M. J. Fichtinger-Schepman, G. Barka, K. Khan, M. H. Lamoree, E. Gout, Ir. A. B. J. M. Dams, Eugene Roets, Mariëtte Ackermans, Willy J. M. Underberg, R. L. A. E. Hamelinck, J. M. Jansen, N. J. Reinhoud, G. Janssen, W. van der Welle, J. Aluoch, P. S. L. Janssen, Dirk T. Witte, R.A. de Zeeuw, Helma M. van der Horst, L. A. Fay
Publikováno v: Pharmacy World & Science. 16:1-8
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7a672e73a11931a53ccd9217db529eaa
https://doi.org/10.1007/bf02336816
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9
Fragmentation of toxicologically relevant drugs in negative-ion liquid chromatography-tandem mass spectrometry
Autor: W M A, Niessen
Publikováno v: Mass spectrometry reviews. 31(6)
Negative-ion LC-MS analysis of drugs is applied far less frequently than positive-ion LC-MS. Data on the interpretation of negative-ion MS-MS spectra are even more scarce. Therefore, following the recent review on the class-specific fragmentation of
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::002d90f1cee89df75db952abf998ad60
https://pubmed.ncbi.nlm.nih.gov/22829116
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10
Fragmentation of toxicologically relevant drugs in positive-ion liquid chromatography-tandem mass spectrometry
Autor: W M A, Niessen
Publikováno v: Mass spectrometry reviews. 30(4)
The identification of drugs and related compounds by LC-MS-MS is an important analytical challenge in several application areas, including clinical and forensic toxicology, doping control analysis, and environmental analysis. Although target-compound
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a97177da18cd834dd6e4674a63f8c8e5
https://pubmed.ncbi.nlm.nih.gov/21294151
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