Zobrazeno 1 - 10
of 215
pro vyhledávání: '"W. Lupton"'
Autor:
Suk Woo Kang, James Antoney, Rebecca L. Frkic, David W. Lupton, Robert Speight, Colin Scott, Colin J. Jackson
Publikováno v:
Biochemistry. 62:873-891
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::920740fd9e855995d0562721c8c59acc
https://doi.org/10.1021/acs.biochem.2c00557
https://doi.org/10.1021/acs.biochem.2c00557
Publikováno v:
Angewandte Chemie.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddff27338eb4d8a22605c3a248c14b50
https://doi.org/10.1002/ange.202303869
https://doi.org/10.1002/ange.202303869
Publikováno v:
ChemBioChem. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84c66aabe4c99d0a969e9422d8edb2c2
https://doi.org/10.1002/cbic.202300195
https://doi.org/10.1002/cbic.202300195
Ene-reductases from the Flavin/Deazaflavin Oxidoreductase (FDOR) family have potential value in biocatalysis as they typically exhibit complementary stereoselectivity to the widely utilized Old Yellow Enzyme (OYE) family, yet they are comparatively p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68fc38c3c53082c9ff7648818de9bc45
https://doi.org/10.1101/2023.02.21.529347
https://doi.org/10.1101/2023.02.21.529347
Autor:
Rania A. Hashad, Edwina Jap, Joanne L. Casey, Y. T. Candace Ho, Alexander Wright, Claudia Thalmann, Mark Sleeman, David W. Lupton, Christoph E. Hagemeyer, Max J. Cryle, Remy Robert, Karen Alt
Publikováno v:
Chemistry – A European Journal. 29
A highly effective 2-step system for site-specific antibody modification and conjugation of the monoclonal antibody Herceptin (commercially available under Trastuzumab) in a cysteine-independent manner was used to generate labelled antibodies for in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6aa46b292ac6830fc4b564b7e295c922
https://doi.org/10.1002/chem.202202491
https://doi.org/10.1002/chem.202202491
Autor:
David W. Lupton, Jeremy T. Maddigan-Wyatt, Mitchell T. Blyth, Joel F. Hooper, Michelle L. Coote, Jhi Ametovski
Publikováno v:
Chemistry – A European Journal. 27:16232-16236
A phosphine-catalyzed approach to pyrrolines has been developed that involves two mechanistically unlinked catalytic processes. The first involves the redox isomerization of amino crotonates to provide access to aliphatic tosyl imines, which then eng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f41ba8242cb7855bde07fd69993d5569
https://doi.org/10.1002/chem.202103224
https://doi.org/10.1002/chem.202103224
Autor:
Yuji Nakano, David W. Lupton
Publikováno v:
Science. 379:439-440
Stable carbenes deliver a carbon atom to simple amides, producing a range of cyclic compounds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc8f69e9f35542ccc9206fb5da682fbd
https://doi.org/10.1126/science.adf2201
https://doi.org/10.1126/science.adf2201
Autor:
Biljana Vujcic, Jessica Wyllie, null Tania, Jed Burns, Keith F. White, Simon Cromwell, David W. Lupton, Jason L. Dutton, Tatiana P. Soares da Costa, Sevan D. Houston
Publikováno v:
Bioorganicmedicinal chemistry letters. 80
The looming threat of a "post-antibiotic era" has been caused by a rapid rise in antibacterial resistance and subsequent depletion of effective antibiotic agents in the clinic. An efficient strategy to address this shortfall lies in the reengineering
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbca15214a77350d00a3c79192cb6e10
https://pubmed.ncbi.nlm.nih.gov/36423825
https://pubmed.ncbi.nlm.nih.gov/36423825
Publikováno v:
Angewandte Chemie (International ed. in English). 61(33)
While the addition of C1-Lewis base enolates to carbonyls and related structures are well established, the related addition to thiocarbonyls compounds are unknown. Herein, we report a reaction cascade in which a C1-pyridinium enolate undergos additio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15af46d28aa2eb2f6b5cb6e3da9dca1f
https://pubmed.ncbi.nlm.nih.gov/35718884
https://pubmed.ncbi.nlm.nih.gov/35718884