Zobrazeno 1 - 10
of 810
pro vyhledávání: '"W. Levy"'
Autor:
Shaowei Zhang, Laura N. Jeffreys, Harshwardhan Poddar, Yuqi Yu, Chuanyang Liu, Kaylee Patel, Linus O. Johannissen, Lingyun Zhu, Matthew J. Cliff, Cunyu Yan, Giorgio Schirò, Martin Weik, Michiyo Sakuma, Colin W. Levy, David Leys, Derren J. Heyes, Nigel S. Scrutton
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-16 (2024)
Abstract Photoreceptor proteins utilise chromophores to sense light and trigger a biological response. The discovery that adenosylcobalamin (or coenzyme B12) can act as a light-sensing chromophore heralded a new field of B12-photobiology. Although mi
Externí odkaz:
https://doaj.org/article/a0f44c530eda465fa74001ba20e7cc49
Autor:
Kritika Dixit, Bhola Rai, Tara Prasad Aryal, Noemia Teixeira de Siqueira-Filha, Raghu Dhital, Manoj Kumar Sah, Ram Narayan Pandit, Govinda Majhi, Puskar Raj Paudel, Jens W. Levy, Job van Rest, Suman Chandra Gurung, Gokul Mishra, Knut Lönnroth, Stephen Bertel Squire, Kristi Sidney Annerstedt, Laura Bonnett, Ahmad Fuady, Maxine Caws, Tom Wingfield
Publikováno v:
BMC Global and Public Health, Vol 2, Iss 1, Pp 1-19 (2024)
Abstract Background The psychosocial consequences of tuberculosis (TB) are key barriers to ending TB globally. We evaluated and compared stigma, depression, and quality of life (QoL) among people with TB diagnosed through active (ACF) and passive (PC
Externí odkaz:
https://doaj.org/article/832ef6a9b7104ad798b255cfe5d1f462
Autor:
Harshwardhan Poddar, Ronald Rios-Santacruz, Derren J. Heyes, Muralidharan Shanmugam, Adam Brookfield, Linus O. Johannissen, Colin W. Levy, Laura N. Jeffreys, Shaowei Zhang, Michiyo Sakuma, Jacques-Philippe Colletier, Sam Hay, Giorgio Schirò, Martin Weik, Nigel S. Scrutton, David Leys
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)
Abstract CarH is a coenzyme B12-dependent photoreceptor involved in regulating carotenoid biosynthesis. How light-triggered cleavage of the B12 Co-C bond culminates in CarH tetramer dissociation to initiate transcription remains unclear. Here, a seri
Externí odkaz:
https://doaj.org/article/001606f7b0874be9a4255441eb03bd98
Autor:
David W. Levy
Here is the first full-length biography of Herbert Croly (1869-1930), one of the major American social thinkers of the twentieth century. David W. Levy explains the origins and impact of Croly's penetrating analysis of American life and tells the sto
Autor:
Suman Chandra Gurung, Kritika Dixit, Bhola Rai, Maxine Caws, Puskar Raj Paudel, Raghu Dhital, Shraddha Acharya, Gangaram Budhathoki, Deepak Malla, Jens W. Levy, Job van Rest, Knut Lönnroth, Kerri Viney, Andrew Ramsay, Tom Wingfield, Buddha Basnyat, Anil Thapa, Bertie Squire, Duolao Wang, Gokul Mishra, Kashim Shah, Anil Shrestha, Noemia Teixeira de Siqueira-Filha
Publikováno v:
Infectious Diseases of Poverty, Vol 8, Iss 1, Pp 1-15 (2019)
Abstract Background The World Health Organization (WHO) End TB Strategy has established a milestone to reduce the number of tuberculosis (TB)- affected households facing catastrophic costs to zero by 2020. The role of active case finding (ACF) in red
Externí odkaz:
https://doaj.org/article/5ab26fca7dcf4682a156395149801561
Autor:
Dr. Safaa M. Kishk, Dr. Kirsty J. McLean, Dr. Sakshi Sood, Darren Smith, Jack W.D. Evans, Prof. Mohamed A. Helal, Prof. Mohamed S. Gomaa, Prof. Ismail Salama, Prof. Samia M. Mostafa, Dr. Luiz Pedro S. de Carvalho, Colin W. Levy, Prof. Andrew W. Munro, Dr. Claire Simons
Publikováno v:
ChemistryOpen, Vol 8, Iss 7, Pp 995-1011 (2019)
Abstract The emergence of untreatable drug‐resistant strains of Mycobacterium tuberculosis is a major public health problem worldwide, and the identification of new efficient treatments is urgently needed. Mycobacterium tuberculosis cytochrome P450
Externí odkaz:
https://doaj.org/article/3aae741715394bd2a5f6041ac6a202cf
Autor:
Allison J. Bancroft, Colin W. Levy, Thomas A. Jowitt, Kelly S. Hayes, Seona Thompson, Edward A. Mckenzie, Matthew D. Ball, Eamon Dubaissi, Aidan P. France, Bruno Bellina, Catherine Sharpe, Aleksandr Mironov, Sheila L. Brown, Peter C. Cook, Andrew S. MacDonald, David J. Thornton, Richard K. Grencis
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
In the study, the authors identify a protein excreted by the parasite Trichuris muris, p43, which can modulate IL-13 function, a key cytokine involved in host protection. These data suggest that p43 may be a novel therapeutic target for both whipworm
Externí odkaz:
https://doaj.org/article/e790a9921fd644c2949b6cd1e5687605
Autor:
Kritika Dixit, Bhola Rai, Tara Prasad Aryal, Gokul Mishra, Noemia Teixeira de Siqueira-Filha, Puskar Raj Paudel, Jens W. Levy, Job van Rest, Suman Chandra Gurung, Raghu Dhital, Olivia Biermann, Kerri Viney, Knut Lonnroth, S Bertel Squire, Maxine Caws, Tom Wingfield
Publikováno v:
Wellcome Open Research, Vol 5 (2020)
Background: WHO’s 2015 End TB Strategy advocates social and economic (socioeconomic) support for TB-affected households to improve TB control. However, evidence concerning socioeconomic support for TB-affected households remains limited, especially
Externí odkaz:
https://doaj.org/article/81171114723c4bd6b2d894f104484c00
Publikováno v:
PLoS ONE, Vol 15, Iss 6, p e0235133 (2020)
We have used a combination of computational and structure-based redesign of the low molecular weight protein tyrosine phosphatase, LMW-PTP, to create new activity towards phosphoinositide substrates for which the wild-type enzyme had little or no act
Externí odkaz:
https://doaj.org/article/96c1e3c4d7184914af684d85e30ef290
Autor:
Mohd Zulkifli Salleh, Vijaykumar Karuppiah, Matthew Snee, Angela Thistlethwaite, Colin W. Levy, David Knight, Jeremy P. Derrick
Publikováno v:
mBio, Vol 10, Iss 3 (2019)
ABSTRACT Natural competence is the term used to describe the uptake of “naked” extracellular DNA by bacteria; it plays a significant role in horizontal genetic exchange. It is associated with type IV pili, and specialized competence pili mediate
Externí odkaz:
https://doaj.org/article/659fe2932b8743b2a327295f116a2110