Zobrazeno 1 - 10
of 154
pro vyhledávání: '"W. L. Matier"'
Autor:
W L, Matier, G, Patil
Publikováno v:
Heart disease (Hagerstown, Md.). 2(2)
Esprolol is a new, potent, beta adrenergic receptor antagonist that is differentiated from available drugs of this class by its rapid onset, short time to peak effect, and relatively short duration of action after sublingual and oral administration.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2a20ff795d50064596a32b209c968e66
https://pubmed.ncbi.nlm.nih.gov/11728252
https://pubmed.ncbi.nlm.nih.gov/11728252
Publikováno v:
Journal of Medicinal Chemistry. 28:295-298
As part of a continuing program of systematically modifying the structure of the class I antiarrhythmic drug changrolin, we synthesized 15 analogues in which the linkage between the two aromatic regions was altered. High antiarrhythmic activity and l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fad73c1ee6f6dddf0d93040c93e5158
https://doi.org/10.1021/jm00381a006
https://doi.org/10.1021/jm00381a006
Publikováno v:
Drug Development Research. 7:221-232
ACC-9129 and ACC-9369 were evaluated in guinea pig isolated atria and trachea and in anesthetized dogs and conscious rabbits for beta-blocking potency, duration of action, and intraocular pressure effects. ACC-9129 showed competitive cardioselective
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f5c26e4b330ca419afbe1d7f5a2d796
https://doi.org/10.1002/ddr.430070304
https://doi.org/10.1002/ddr.430070304
Autor:
W. L. Matier, W. T. Comer
Publikováno v:
The Journal of Organic Chemistry. 39:3080-3084
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::95f67158613b8baeb46be693f56c701a
https://doi.org/10.1021/jo00935a004
https://doi.org/10.1021/jo00935a004
Publikováno v:
J. Chem. Soc. B. :260-266
Reaction of 2,2′-di(hydroxyamino)diaryl sulphones with sodium hydroxide in aqueous dioxan at 20° yields dibenzo [b,f][1,4,5]thiadiazepine 5,11,11-trioxides (X), phenazine 5-oxides (XIV), and phenazine 5,10-dioxides (XV). The formation of the phena
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53f4411b44d381462e70bdd0c79467bc
https://doi.org/10.1039/j29660000260
https://doi.org/10.1039/j29660000260
Publikováno v:
Journal of Medicinal Chemistry. 15:538-541
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81b1cc6dcb23286e1e35cacb7016baeb
https://doi.org/10.1021/jm00275a025
https://doi.org/10.1021/jm00275a025
Publikováno v:
J. Chem. Soc. C. :654-661
Treatment of 2-(hydroxyamino)aryl phenyl sulphones or bis-(2-hydroxyaminoaryl) sulphones with aqueous sodium hydroxide at 20° gives 2-hydroxy-2′-(arylsulphonyl)azoxybenzenes (V) and (VII) and arenesulphonate anions. The hydroxy-group in the azoxy-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6da4773922272ae1bc5b4c073f7f033e
https://doi.org/10.1039/j39710000654
https://doi.org/10.1039/j39710000654
Autor:
Chmil, Vojtěch, Živná, Natálie, Milanová, Marcela, Filipová, Alžběta, Pejchal, Jaroslav, Prchal, Lukáš, Muthná, Darina, Řeháček, Vít, Řezáčová, Martina, Marek, Jan, Tichý, Aleš, Havelek, Radim
Publikováno v:
RSC Medicinal Chemistry; Aug2024, Vol. 15 Issue 8, p2855-2866, 12p
Publikováno v:
Epilepsia. 30
ACC-9653, the disodium phosphate ester of 3-hydroxymethyl-5,5-diphenylhydantoin, is a prodrug of phenytoin with advantageous physicochemical properties. ACC-9653 is rapidly converted enzymatically to phenytoin in vivo. ACC-9653 and phenytoin sodium h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b408c4fb519467b91983f7abdccd605
https://pubmed.ncbi.nlm.nih.gov/2767010
https://pubmed.ncbi.nlm.nih.gov/2767010
Publikováno v:
Chemischer Informationsdienst. 15
Unter Verwendung der Chlorphthalazine (I) erhalt man gemas Formelschema die Verbindungen (IV) und (VII).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f58126f98c8feb2562f02b9536e99e4
https://doi.org/10.1002/chin.198408197
https://doi.org/10.1002/chin.198408197