Zobrazeno 1 - 10
of 92
pro vyhledávání: '"W. L. Maloy"'
Autor:
M. Beyermann, E. Krause, W L Maloy, Richard M. Epand, M. Dathe, D L MacDonald, M. Bienert, Torsten Wieprecht
Publikováno v:
Biochemistry. 36:12869-12880
To investigate the influence of the angle subtended by the positively charged helix face on membrane activity, six amphipathic alpha-helical peptides with angles between 80 degrees and 180 degrees, but with retained hydrophobicity, hydrophobic moment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cf41ece71a89dab1cdc57c95aa16f3e
https://doi.org/10.1021/bi971398n
https://doi.org/10.1021/bi971398n
Autor:
D L MacDonald, W L Maloy, Eberhard Krause, Torsten Wieprecht, Michael Beyermann, Margitta Dathe, Bienert M
Publikováno v:
Biochemistry. 36:6124-6132
The magainins are antibacterial peptides from the skin of Xenopus laevis. They show a broad range of activity against prokaryotic cells but lyse eukaryotic cells poorly. To elucidate the influence of peptide hydrophobicity on membrane activity and se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57e94239dc8fa0f53b5e7de5f3478035
https://doi.org/10.1021/bi9619987
https://doi.org/10.1021/bi9619987
Publikováno v:
Biochemistry. 35:12733-12741
Magainins are cationic, membrane-active peptides which show broad-spectrum antimicrobial activity. We have investigated the secondary structure and location of an analogue of magainin 2 in synthetic phospholipid bilayers using a combination of Fourie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd5713ecfc281a76096ddb89b05d572d
https://doi.org/10.1021/bi961468a
https://doi.org/10.1021/bi961468a
Publikováno v:
International Journal of Cancer. 60:280-284
Magainin peptides and model amphipathic peptides exhibit antibiotic activity and are also cytolytic for transformed human cells. Here we demonstrate in vitro that MSI-511 (an all-D amino-acid model magainin peptide) and MSI-130 (a margainin analogue)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1750719031fa27db9acb2197bcd84daa
https://doi.org/10.1002/ijc.2910600225
https://doi.org/10.1002/ijc.2910600225
Publikováno v:
Biopolymers. 37:105-122
Host defense peptides are widely distributed in nature, being found in species from bacteria to humans. The structures of these peptides from insects, horseshoe crabs, frogs, and mammals are known to have the common features of a net cationic charge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87cb0e1a907f3af1403b114027dbd64b
https://doi.org/10.1002/bip.360370206
https://doi.org/10.1002/bip.360370206
Publikováno v:
The Journal of Experimental Medicine
Distinct combinations of class II major histocompatibility complex (MHC) alpha and beta chains show widely varying efficiencies of cell surface expression in transfected cells. Previous studies have analyzed the regions of the class II chains that ar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0db791c6c8270c0b3e2df51c63748ba
https://doi.org/10.1084/jem.174.4.799
https://doi.org/10.1084/jem.174.4.799
Publikováno v:
Proceedings of the National Academy of Sciences. 88:3952-3956
Extracts of the bovine tracheal mucosa have an abundant peptide with potent antimicrobial activity. The 38-amino acid peptide, which we have named tracheal antimicrobial peptide (TAP), was isolated by a sequential use of size-exclusion, ion-exchange,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca1e9b8190451df5d148d6fc70cf1a25
https://doi.org/10.1073/pnas.88.9.3952
https://doi.org/10.1073/pnas.88.9.3952
Autor:
Barbara B. Knowles, M Lewis, W L Maloy, Rob Anderson, Yuetsu Tanaka, Janice Milici, Satvir S. Tevethia
Publikováno v:
Scopus-Elsevier
Five distinct cytotoxic T-lymphocyte (CTL) recognition sites were identified in the simian virus 40 (SV40) T antigen by using H-2b cells that express the truncated T antigen or antigens carrying internal deletions of various sizes. Four of the CTL re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9afd1d13fd63f12b01abdc8acc5f3985
https://doi.org/10.1128/jvi.64.3.1192-1200.1990
https://doi.org/10.1128/jvi.64.3.1192-1200.1990
Publikováno v:
European Journal of Immunology. 20:299-305
Cell surface-expressed receptors are often multichain complexes. One of these, the T cell receptor (TcR) alpha/beta-CD3 complex, is known to contain at least seven chains: the alpha and beta TcR chains plus the gamma, delta, epsilon and two zeta chai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01a84a21eb6801f2b9ed0eb1391942ea
https://doi.org/10.1002/eji.1830200211
https://doi.org/10.1002/eji.1830200211
Publikováno v:
Peptide Science — Present and Future ISBN: 0792352718
Results and discussion Cationic, amphipathic, α-helical peptides are membrane active and able to disturb the barrier function of cell membranes [1, 2]. Some of the peptides possess antibacterial selectivity and are therefore of potential clinical re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d7a9a38babee121204e94e1cd9f9147
https://doi.org/10.1007/0-306-46864-6_230
https://doi.org/10.1007/0-306-46864-6_230
