Zobrazeno 1 - 10
of 98
pro vyhledávání: '"W. L. Dewey"'
Autor:
T. R. Baird, H. I. Akbarali, W. L. Dewey, H. Elder, M. Kang, S. A. Marsh, M. R. Peace, J. L. Poklis, E. J. Santos, S. S. Negus
Publikováno v:
Psychopharmacology (Berl)
RATIONALE: Tianeptine is a mu-opioid receptor (MOR) agonist with increasing reports of abuse in human populations. Preclinical data regarding the abuse potential and other opioid-like adverse effects of tianeptine at supratherapeutic doses are sparse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bcf84a74e020443c56e95f9d78dd15d
https://pubmed.ncbi.nlm.nih.gov/35211768
https://pubmed.ncbi.nlm.nih.gov/35211768
Autor:
W. L. Dewey
Publikováno v:
Chemical and Biological Aspects of Drug Dependence ISBN: 9780429260629
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f8ab36dba6c2a4b1fefef1146b2aa5d
https://doi.org/10.1201/9780429260629-6
https://doi.org/10.1201/9780429260629-6
Publikováno v:
Neurogastroenterology & Motility. 26:1361-1367
Opioid-induced constipation is a major clinical problem. The effects of morphine, and other narcotics, on the gastrointestinal tract persist over long-term use thus limiting the clinical benefit of these excellent pain relievers. The effects of opioi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::863e10eb32fcd88734fc94bb798bda4d
https://doi.org/10.1111/nmo.12443
https://doi.org/10.1111/nmo.12443
Publikováno v:
Agents and Actions. 31:157-163
The antinociceptive effects ofΔ (THC-7-oic) acid have been investigated further with particular regard to the influence of certain experimental parameters in the hot plate test. These included the degree of the thermal stimulus, the nature of the ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee7b3b5ed11781d144f25a52fe35eeb1
https://doi.org/10.1007/bf02003237
https://doi.org/10.1007/bf02003237
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 270(3)
In studying the interactions between handling mice and their subsequent analgesic response to an intrathecally (i.t.) administered mu-opioid agonist, DAMGO, it was found that suspending ICR mice by the tail for 1, 5, or 20 sec, 10 min before the tail
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bcc80422fbf8761f6f4449eb1029bca9
https://pubmed.ncbi.nlm.nih.gov/7932169
https://pubmed.ncbi.nlm.nih.gov/7932169
Autor:
R, Natsuki, W L, Dewey
Publikováno v:
Arukoru kenkyu to yakubutsu izon = Japanese journal of alcohol studiesdrug dependence. 28(5)
The cisterna magna of dogs anesthetized with sodium Surital was fitted with a cannula, and cerebrospinal fluid (CSF) was withdrawn before (control) and one hour after the s.c. injection of 10 mg/kg of morphine sulfate (morphine). The CSF from control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4fe78aa8a417749e547999b31731903a
https://pubmed.ncbi.nlm.nih.gov/8267521
https://pubmed.ncbi.nlm.nih.gov/8267521
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 266(3)
To the authors' knowledge, the effect of i.t. administered calcium on thermoregulation in mice has not been investigated. Calcium administration (i.t.) induced hypothermia in mice. It was found that calcitonin gene-related peptide (CGRP) (i.t.) also
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d0f96efa84ec168d481004682a0e1961
https://pubmed.ncbi.nlm.nih.gov/8371146
https://pubmed.ncbi.nlm.nih.gov/8371146
Publikováno v:
Biochemical pharmacology. 45(2)
The hypoglycemic effect of morphine (40 micrograms) injected intrathecally (i.t.) was studied with regard to disposition of i.v. [14C]glucose and [3H]2-deoxyglucose and was compared with the effects of two other hypoglycemic agents, insulin (1 IU/kg,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1a2fa6c2a55a9704da3737417b611c3e
https://pubmed.ncbi.nlm.nih.gov/8435095
https://pubmed.ncbi.nlm.nih.gov/8435095
Autor:
F L, Smith, W L, Dewey
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 262(3)
Mice injected with calcium in the intrathecal (i.t.) space display dose-dependent antinociception in the tail-flick test. The aims of this study were to evaluate whether endogenous opioids mediate the antinociceptive effects of calcium (i.t.) and to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::404b3530adb3a053d323313ecdc58b80
https://pubmed.ncbi.nlm.nih.gov/1326632
https://pubmed.ncbi.nlm.nih.gov/1326632
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 260(1)
Administration of i.t. calcium has been shown to produce effects which are opposite to those observed when calcium is injected into the brain. The purpose of this study was to elucidate the mechanism of the antinociceptive action of calcium (i.t.). I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4092a91929376176e824873852471ffd
https://pubmed.ncbi.nlm.nih.gov/1346158
https://pubmed.ncbi.nlm.nih.gov/1346158