Zobrazeno 1 - 10
of 205
pro vyhledávání: '"W. Kuhnz"'
Autor:
Alberto Lanzini, W. Kuhnz, Santo Scalia, Ornella Baisini, Horst-Dietmar Tauschel, Felice Petraglia, Federica Benini, Hanns-Ulrich Marschall, Gabriele Brunetti
Publikováno v:
European Journal of Clinical Pharmacology. 60:481-487
Contraception is recommended for female patients during ursodeoxycholic acid (UDCA) treatment for the potential teratogenic effect of this bile acid, and the aim of our study was to determine whether this treatment affects the bioavailability of ethi
Publikováno v:
Toxicology in Vitro. 12:353-364
We report investigations into the potential of the steroid hormones chlormadinone acetate (CMA), cyproterone acetate (CPA), dexamethasone (DEX), estradiol (E 2 ), ethinylestradiol (EE 2 ), gestodene (GEST), levonorgestrel (LNG), megestrol acetate (MG
Publikováno v:
European Journal of Clinical Pharmacology. 53:75-80
To investigate a possible age-dependence of the pharmacokinetics of cyproterone acetate following single oral administration.Twenty eight healthy men between 22 and 74 years of age received a single oral dose of 100 mg cyproterone acetate. The pharma
Publikováno v:
Geburtshilfe und Frauenheilkunde. 56:221-225
The effect of a 26 day oestrogen-gestogene sequence therapy on double endometrium thickness, uterus size, blood flow in the uterine blood vessels (pulsatility and resistance index), serum concentration of FSH, LH and SHBG and on vaginal cytology of p
Autor:
W. Kuhnz, B. Löfberg
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 55:129-133
The measurement of the urinary excretion ratio of 6 beta-hydroxycortisol (6 beta-OHC)/cortisol was used as a non-invasive method to investigate possible changes in the activity of drug-metabolizing enzymes in women receiving different oral contracept
Publikováno v:
Advances in Contraception. 11:207-225
The study was performed in 14 young women. The combination oral contraceptive contained 75 microgram gestodene (GSD) and 20 microgram ethinyl estradiol (EE2) per dosage unit. The volunteers received a single dose on day 21 of a treatment-free precycl
Autor:
Andreas Baumann, Hartmut Blode, Helmut Biere, Rasoul S. Kerdar, W. Kuhnz, Margarete Brudny-Klöppel
Publikováno v:
Carcinogenesis. 16:1835-1841
Cyproterone acetate (CPA) is a synthetic steroid hormone used in the therapy of prostate cancer in men and different forms of acne and hirsutism in women. CPA has been shown by 32P-postlabeling analysis to bind covalently to hepatic DNA of rats in vi
Publikováno v:
Contraception. 50:563-579
The pharmacokinetics of levonorgestrel (LNG) and ethinylestradiol (EE2) were determined in 14 healthy women (age 18 to 27 years) during a treatment period of three months with a tri-step combination oral contraceptive (Triquilar). Prior to this treat
Publikováno v:
Contraception. 49:255-263
Norgestimate is a novel progestin which undergoes both in vivo and in vitro metabolic conversions to a number of metabolites, of which the most important are levonorgestrel acetate, levonorgestrel oxime and levonorgestrel itself. It has been claimed
Publikováno v:
Contraception. 48:576-590
The effects of daily oral administration of a high dose of 10 mg norethisterone acetate (NET-Ac.)/kg/day over 14 weeks on serum lipid and lipoprotein parameters as well as on blood coagulation were investigated in female monkeys (M. fascicularis). Me