EXPLAINING TOMATO FRUIT GROWTH BY A MULTI-SCALE MODEL ON REGULATION OF CELL DIVISION, CELL GROWTH AND CARBOHYDRATE DYNAMICS

Autor: Julienne Fanwoua, Leo F. M. Marcelis, R.C.O. Okello, P.H.B. de Visser, Ep Heuvelink, Xinyou Yin, Paul C. Struik, W. Kromdijk

Publikováno v: Scopus-Elsevier
Proceedings of the IV International Symposium on Models for Plant Growth, Environmental Control and Farm Management in Protected Cultivation-HortiModel2012, Nanjing, 04-04 November 2012, China
Proceedings of the IV International Symposium on Models for Plant Growth, Environmental Control and Farm Management in Protected Cultivation-HortiModel2012, Nanjing, 04-04 November 2012, China. ISHS

A multi-scale approach to model tomato fruit growth is proposed, in order to account for the interaction between gene functioning and growth conditions, and, ultimately, to explain the fruit phenotype of various genotypes in diverse growth environmen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5512db5952babd2d67a19c905895387
https://doi.org/10.17660/actahortic.2012.957.18

Treatment of Immunocompromised, Critically Ill Patients with Influenza A H1N1 Infection with a Combination of Oseltamivir, Amantadine, and Zanamivir

Autor: Marcel P. H. van den Broek, Annemarie M. J. Wensing, Monique C. Minnema, Dylan W. de Lange, Pieter-Jan A. Haas, Wouter J. Meijer, W. Kromdijk, Charles A. Boucher

Publikováno v: Case Reports in Infectious Diseases
Case Reports in Infectious Diseases, 2015
Case Reports in Infectious Diseases, Vol 2015 (2015)

Immunocompromised patients are at increased risk of complications of influenza virus infection. We report on two critically ill patients on immunosuppressive medication with influenza pneumonia. In both patients, oseltamivir monotherapy did not resul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e1f161c7222c60ce220bd7b3a3c2ab4
https://doi.org/10.1155/2015/504975

INNOVATION-ORIENTED ANALYSIS OF CRITICAL CONTROL POINTS (IACCP): WHO WISHES TO SOLVE SWEET PEPPER YIELD OSCILLATIONS?

Autor: O. van Kooten, H.E. Schepers, W. Kromdijk

Publikováno v: Acta Horticulturae, 712, 83-90
Acta Horticulturae 712 (2006)

A generic program for mathematical model-supported innovation profiling in fresh food supply chains is presented. Building on top of a crop growth model, strategies to address the problem of sweet pepper yield oscillations (flushes) are analysed quan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fcfe9bbad3b3fbf7c5579bfc33ce335
https://doi.org/10.17660/actahortic.2006.712.7

Quantitative determination of oseltamivir and oseltamivir carboxylate in human fluoride EDTA plasma including the ex vivo stability using high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry

Autor: A. D. R. Huitema, Jos H. Beijnen, Hilde Rosing, M P H van den Broek, W. Kromdijk

Publikováno v: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

Oseltamivir, the ethyl ester prodrug of the neuramidase inhibitor oseltamivir carboxylate, is licensed for the treatment of patients with influenza virus infection. Here we describe the development and validation of an assay for the simultaneous quan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce72997a65b6897a3e5a373d9a72bc8b
https://pubmed.ncbi.nlm.nih.gov/22418071

Phase I, pharmacokinetic study of temsirolimus in combination with nelfinavir in patients with solid tumors

Autor: J.H.M. Schellens, W. Kromdijk, Heinz-Josef Klümpen, M. E. Kemper, D.J. Richel, A. D. R. Huitema

Publikováno v: Journal of Clinical Oncology. 28:2572-2572

2572 Background: Temsirolimus (CCI-779, TEM) is a selective inhibitor of mTOR with anticancer activity in a limited number of cancer types. A potential mechanism of drug resistance of TEM is feedba...

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6a500e3273b848d41c342018edbc6800
https://doi.org/10.1200/jco.2010.28.15_suppl.2572