Zobrazeno 1 - 10
of 73
pro vyhledávání: '"W. Karpiesiuk"'
Publikováno v:
Journal of Veterinary Pharmacology and Therapeutics. 35:265-274
Toltrazuril sulfone (ponazuril) is a triazine-based antiprotozoal agent with clinical application in the treatment of equine protozoal myeloencephalomyelitis (EPM). In this study, we synthesized and determined the bioavailability of a sodium salt for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4de60a16da504244aa2055a99bdf8d14
https://doi.org/10.1111/j.1365-2885.2011.01315.x
https://doi.org/10.1111/j.1365-2885.2011.01315.x
Autor:
Andreas F. Lehner, Charlie Hughes, David E. Granstrom, Levent Dirikolu, W. Karpiesiuk, Thomas Tobin
Publikováno v:
Journal of Veterinary Pharmacology and Therapeutics. 32:368-378
Triazine-based antiprotozoal agents are known for their lipophylic characteristics and may therefore be expected to be well absorbed following oral administration. However, although an increase in lipid solubility generally increases the absorption o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d3f3ac7b6ad1044e01680debbe5e1bc
https://doi.org/10.1111/j.1365-2885.2008.01053.x
https://doi.org/10.1111/j.1365-2885.2008.01053.x
Autor:
Richard S. Gates, Thomas Tobin, M. Fisher, Andreas F. Lehner, W. E. Woods, Levent Dirikolu, W. Karpiesiuk, J. D. Harkins
Publikováno v:
Journal of Veterinary Pharmacology and Therapeutics. 32:66-78
Pyrilamine is an antihistamine used in human and veterinary medicine. As antihistamines produce central nervous system effects in horses, pyrilamine has the potential to affect the performance of racehorses. In the present study, O-desmethylpyrilamin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bf7b430a3451fe38e6eee456ec2c490
https://doi.org/10.1111/j.1365-2885.2008.01005.x
https://doi.org/10.1111/j.1365-2885.2008.01005.x
Autor:
Andreas F. Lehner, J. Boyles, L. Dirikolu, W. Karpiesiuk, W. E. Woods, Charlie Hughes, F. C. Camargo, Thomas Tobin, Jeffrey M. Bosken, A. Troppmann, J. D. Harkins
Publikováno v:
Journal of Analytical Toxicology. 28:553-562
Amitraz (N'-(2,4-dimethylphenyl)-N-[[(2,4-dimethylphenyl)imino]methyl]-N-methyl-methanimidamide) is an alpha-2 adrenergic agonist used in veterinary medicine primarily as a scabicide- or acaricide-type insecticide. As an alpha-2 adrenergic agonist, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8dc3bef88ba898083df9820bfc1a76d9
https://doi.org/10.1093/jat/28.7.553
https://doi.org/10.1093/jat/28.7.553
Autor:
W. E. Woods, Andreas F. Lehner, W. Karpiesiuk, J. Boyles, Charlie Hughes, J. D. Harkins, Thomas Tobin, F. C. Camargo
Publikováno v:
Chromatographia. 60:371-378
Trimetoquinol (TMQ) (1-(3’,4’,5’-trimethoxybenzyl)-6,7-dihydroxy-1,2,3,4-tetrahydroisoquinoline, m.w. 345) is the prototype tetrahydroisoquinoline pharmaceutical. TMQ is marketed as a bronchodilator in human medicine; in horse racing, TMQ is li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e9b84cbc0f036e248b1f8396f870d15c
https://doi.org/10.1365/s10337-004-0405-7
https://doi.org/10.1365/s10337-004-0405-7
Autor:
W. Karpiesiuk, Charlie Hughes, W. E. Woods, J. D. Harkins, A. Troppmann, Thomas Tobin, J. Bosken, F. C. Camargo, Andreas F. Lehner, J. Boyles
Publikováno v:
Chromatographia. 59:S79-S84
Salmeterol is a β2-adrenergic agonist and an Association of Racing Commissioners International (ARCI) class 3 drug. Trade names of its xinafoate salt are Arial (Dompe), Salmetedur (Menarini), and Serevent (Glaxo). Salmeterol is routinely used to inc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29836e8bd047e42276ae26262414ad41
https://doi.org/10.1365/s10337-004-0249-1
https://doi.org/10.1365/s10337-004-0249-1
Autor:
W. Karpiesiuk, Andreas F. Lehner, J. Boyles, W. E. Woods, F. C. Camargo, J. D. Harkins, Charlie Hughes, Thomas Tobin
Publikováno v:
Chromatographia. 59:S95-S103
Dizocilpine ([+]-10,11-dihydro-5-methyl-5H-dibenzo[a,d]cyclohepten-5,10-imine), is a potent and selective NMDA (N-methyl-D-aspartate) receptor antagonist, which acts by blocking receptor ion channels. Dizocilpine is pharmacologically related to ketam
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::179bcdc0ce65b41511fecdcc6abc5900
https://doi.org/10.1365/s10337-004-0247-3
https://doi.org/10.1365/s10337-004-0247-3
Autor:
N. E. Robinson, Andreas F. Lehner, Thomas Tobin, W. E. Woods, M. Fisher, W. Karpiesiuk, J. D. Harkins, L. Dirikolu
Publikováno v:
Journal of Analytical Toxicology. 25:280-287
Clenbuterol is a beta2 agonist/antagonist bronchodilator, and its identification in post-race samples may lead to sanctions. The objective of this study was to develop a specific and highly sensitive serum quantitation method for clenbuterol that wou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beb9fb46221b4216a2253509a5a26c69
https://doi.org/10.1093/jat/25.4.280
https://doi.org/10.1093/jat/25.4.280
Autor:
L. Dirikolu, Thomas Tobin, Andreas F. Lehner, J. Boyles, J. D. Harkins, W. G. Carter, W. Karpiesiuk, W. E. Woods
Publikováno v:
Journal of Veterinary Pharmacology and Therapeutics. 24:89-98
This report evaluates the pharmacological responses, urinary detection and mass spectral confirmation of ropivacaine in horses. Ropivacaine, a potent local anesthetic (LA) recently introduced in human medicine, has an estimated highest no-effect dose
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ef2ecb34b1dd58b38310b05931f8c0
https://doi.org/10.1046/j.1365-2885.2001.00314.x
https://doi.org/10.1046/j.1365-2885.2001.00314.x
Autor:
L. Dirikolu, A.F. Lehner, W. Karpiesiuk, J.D. Harkins, W.E. Woods, W.G. Carter, J. Boyles, M. Fisher, T. Tobin
Publikováno v:
Journal of Veterinary Pharmacology and Therapeutics. 23:215-222
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::071b4bc68fbc6a0b1786c670ee675701
https://doi.org/10.1046/j.1365-2885.2000.t01-1-00281.x
https://doi.org/10.1046/j.1365-2885.2000.t01-1-00281.x