Zobrazeno 1 - 10 of 116 pro vyhledávání: '"W. KWAPISZEWSKI"'
2
Synthesis, structures and biological activity of some N1-substituted 4-oxocinnolines
Autor: A, Stańczak, W, Kwapiszewski, Z, Ochocki, W, Lewgowd, A, Szadowska, W, Pakulska, M L, Główka
Publikováno v: Acta poloniae pharmaceutica. 52(2)
The method of preparation of N1-substituted 4-hydroxycinnolines is described, by alkylation with methyl bromopropionate of the corresponding 4-hydroxycinnolines. The obtained esters were further converted into amides and hydrazides. The effect of sev
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fc2de5a4c45e9a47c5702177735d4ec1
https://pubmed.ncbi.nlm.nih.gov/8960242
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3
Synthesis, structures and biological activity of some 4-amino-3-cinnolinecarboxylic acid derivatives, Part 1
Autor: A, Stańczak, W, Kwapiszewski, W, Lewgowd, Z, Ochocki, A, Szadowska, W, Pakulska, M, Główka
Publikováno v: Die Pharmazie. 49(12)
This work describes the synthesis of 4-amino-3-cinnolinecarboxamides, which were then hydrolyzed to corresponding 4-amino-3-cinnolinecarboxylic acids. Several compounds were tested for their antibacterial and antifungal activity, and for the central
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::9fea26f94d9fc2f259fa64830b7c7e63
https://pubmed.ncbi.nlm.nih.gov/7838879
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4
Synthesis and action on the central nervous system of some N2-substituted cinnoline derivatives
Autor: A, Stańczak, W, Kwapiszewski, A, Szadowska, W, Pakulska
Publikováno v: Die Pharmazie. 49(6)
Alkylation of 4-hydroxycinnolines using ethyl bromoacetate resulted in N2-substituted acetic acids. These acids were converted to esters and amides. Some of the obtained acids were reduced with zinc dust to give 4-oxo-1,2,3,4-tetrahydro-2-cinnolineac
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::22c455c7de6ae04dcf3746dc1a9dbfae
https://pubmed.ncbi.nlm.nih.gov/8047541
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7
Synthesis of L-cysteine derivatives of immunotropic activity
Autor: W, Kwapiszewski, M, Sokołowska-Muszyńska, J, Iliaszenko, L, Borkowski, M, Witczak
Publikováno v: Archivum immunologiae et therapiae experimentalis. 37(1-2)
The new immunosuppressive and anti-inflammatory agents have been searched in a group of the synthetic L-cysteine and 3-acetyl-thiazolidine-4-carboxylic acid derivatives. Synthesis of 17 compounds is reported.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0618cefa08bcd78ef3d4c8f326fca0de
https://pubmed.ncbi.nlm.nih.gov/2619507
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