Zobrazeno 1 - 10
of 34
pro vyhledávání: '"W. K. Lutz"'
Autor:
H. Grunicke, W. Pyerin, G. Eisenbrand, K. Havemann, H. M. Rabes, K. M�lling, M. Schwab, W. K. Lutz, J. Wahrendorf, V. Schirrmacher, K. Bosslet
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 120:179-185
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcf6df5edb9d071214724ee7563d8050
https://doi.org/10.1007/bf01202199
https://doi.org/10.1007/bf01202199
Autor:
W K, Lutz
Publikováno v:
Mutation research. 443(1-2)
Chemical carcinogens in the diet cannot explain the cancer incidence attributed by epidemiologists to dietary factors when the calculation is based on average exposure levels and conservative estimates of carcinogenic potencies. In a previous review,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ffceb87b60495d455c804d34d506f56b
https://pubmed.ncbi.nlm.nih.gov/10415443
https://pubmed.ncbi.nlm.nih.gov/10415443
Autor:
R C, Gupta, W K, Lutz
Publikováno v:
Mutation research. 424(1-2)
It is undisputed today that DNA is constantly being damaged in the absence of any exposure to genotoxic carcinogens by a specific treatment or a particular habit. Damaging processes include endogenous and unavoidable exogenous sources. The list compr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6117e9710ef7d2c3792162d499cd0893
https://pubmed.ncbi.nlm.nih.gov/10232953
https://pubmed.ncbi.nlm.nih.gov/10232953
Autor:
M. van den Broek, S. Vamvakas, Rolf M. Zinkernagel, David Kägi, Hans Hengartner, Cornelis J. M. Melief, W. K. Lutz, Ferry Ossendorp, René E. M. Toes
Publikováno v:
The Journal of Experimental Medicine
Immune surveillance against tumors usually depends on T cell recognition of tumor antigens presented by major histocompatibility complex (MHC) molecules, whereas MHC class I- tumors may be controlled by natural killer (NK) cells. Perforin-dependent c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07bbad4b691208f7abb6cc06911cc268
Publikováno v:
Cancer research. 53(15)
The question addressed was whether stimulation of cell proliferation could be responsible for tumor induction in the forestomach by styrene 7,8-oxide (SO). Male F344 rats were treated for 4 weeks with 0, 137, 275, and 550 mg/kg SO by p.o. gavage 3 ti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ebc644ebd18eb7c1ed33407f6dd1554b
https://pubmed.ncbi.nlm.nih.gov/8339254
https://pubmed.ncbi.nlm.nih.gov/8339254
Publikováno v:
IARC scientific publications. (124)
Using DNA modified with [7-3H]styrene 7,8-oxide (SO) in vitro we have standardized the 32P-postlabelling assay for detecting SO-DNA adducts. Nuclease P1-enriched adducts were 32P-labelled and purified by high-salt (4.0 M ammonium formate, pH 6.1) C18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0d5bcacc9f9152b9f72ce78ce3384fe7
https://pubmed.ncbi.nlm.nih.gov/8225485
https://pubmed.ncbi.nlm.nih.gov/8225485
Autor:
W. K. Lutz, J. Schlatter
Publikováno v:
Public Education on Diet and Cancer ISBN: 9789401053273
Doll and Peto (1981), in their review on ‘Quantitative Estimates of Avoidable Risks of Cancer’ state that “it may be possible to reduce US cancer death rates by practicable dietary means by as much as 35%”. This reduction results from a 90% r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bc686c0003adb5bb7d376c8a86ad68f
https://doi.org/10.1007/978-94-011-2986-2_2
https://doi.org/10.1007/978-94-011-2986-2_2
Publikováno v:
IARC scientific publications. (105)
The alkylating potency of unstable N-nitrosamino acids and N-nitrosopeptides was investigated in vitro using 4-(para-nitrobenzyl)pyridine (NBP) as nucleophile. Of the amino acids, Met and those with an aromatic side chain were the most potent. The re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ee45e399aa0ec2dd1ca57572d194469c
https://pubmed.ncbi.nlm.nih.gov/1855885
https://pubmed.ncbi.nlm.nih.gov/1855885
Autor:
W. K. Lutz
Publikováno v:
Risk Assessment in Chemical Carcinogenesis ISBN: 9783540541493
The cancer risk from exposure to a chemical carcinogen is determined by the — Exposure conditions (dose, time and duration of exposure) — Potency of the carcinogen (dose-tumor incidence relationship) — Host reaction (individual susceptibility)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94384ebb4b011018a6891dc2b73407e6
https://doi.org/10.1007/978-3-642-84529-1_3
https://doi.org/10.1007/978-3-642-84529-1_3
Autor:
W K, Lutz
Publikováno v:
Advances in experimental medicine and biology. 283
Mechanistic possibilities responsible for nonlinear shapes of the dose-response relationship in chemical carcinogenesis are discussed. (i) Induction and saturation of enzymatic activation and detoxification processes and of DNA repair affect the rela
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a49e84c062ce6545923c2c1f22d16b89
https://pubmed.ncbi.nlm.nih.gov/2068982
https://pubmed.ncbi.nlm.nih.gov/2068982