Zobrazeno 1 - 10
of 52
pro vyhledávání: '"W. John Watkins"'
Autor:
Maria Nieto-Rosado, Kirsty Sands, Edward A. R. Portal, Kathryn M. Thomson, Maria J. Carvalho, Jordan Mathias, Rebecca Milton, Calie Dyer, Chinenye Akpulu, Ian Boostrom, Patrick Hogan, Habiba Saif, Ana D. Sanches Ferreira, Thomas Hender, Barbra Portal, Robert Andrews, W. John Watkins, Rabaab Zahra, Haider Shirazi, Adil Muhammad, Syed Najeeb Ullah, Muhammad Hilal Jan, Shermeen Akif, Kenneth C. Iregbu, Fatima Modibbo, Stella Uwaezuoke, Lamidi Audu, Chinago P. Edwin, Ashiru H. Yusuf, Adeola Adeleye, Aisha S. Mukkadas, Jean Baptiste Mazarati, Aniceth Rucogoza, Lucie Gaju, Shaheen Mehtar, Andrew N. H. Bulabula, Andrew Whitelaw, Lauren Roberts, Grace Chan, Delayehu Bekele, Semaria Solomon, Mahlet Abayneh, Gesit Metaferia, Group BARNARDS, Timothy R. Walsh
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Hospital surfaces can harbour bacterial pathogens, which may disseminate and cause nosocomial infections, contributing towards mortality in low- and middle-income countries (LMICs). During the BARNARDS study, hospital surfaces from neonatal
Externí odkaz:
https://doaj.org/article/fb3f6d5c019a46c0ac7a6466db812ad7
Autor:
Eleftheria Kodosaki, W. John Watkins, Sam Loveless, Karim L. Kreft, Aidan Richards, Valerie Anderson, Lisa Hurler, Neil P. Robertson, Wioleta M. Zelek, Emma C. Tallantyre
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-15 (2024)
Abstract Establishing biomarkers to predict multiple sclerosis diagnosis and prognosis has been challenging using a single biomarker approach. We hypothesised that a combination of biomarkers would increase the accuracy of prediction models to differ
Externí odkaz:
https://doaj.org/article/e913db9920294deca5839127a7910fbd
Autor:
Christopher W. Course, Philip A. Lewis, Sarah J. Kotecha, Michael Cousins, Kylie Hart, Kate J. Heesom, W. John Watkins, Sailesh Kotecha
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Preterm-born children are at risk of long-term pulmonary deficits, including those who developed bronchopulmonary dysplasia (BPD) in infancy, however the underlying mechanisms remain poorly understood. We characterised the exhaled breath con
Externí odkaz:
https://doaj.org/article/760399c5e4e34e9ab59518603979260d
Autor:
Rory Taylor, Chengyuan Zhang, Deslit George, Sarah Kotecha, Mariam Abdelghaffar, Thorsten Forster, Patricia Dos Santos Rodrigues, Alexander C. Reisinger, Daniel White, Fergus Hamilton, W. John Watkins, David M. Griffith, Peter Ghazal
Publikováno v:
EBioMedicine, Vol 100, Iss , Pp 104981- (2024)
Summary: Background: Mechanistic studies have established a biological role of sterol metabolism in infection and immunity with clinical data linking deranged cholesterol metabolism during sepsis with poorer outcomes. In this systematic review we ass
Externí odkaz:
https://doaj.org/article/c4ca1ee0b24e424d8cba2b2e11ad2989
Autor:
Christopher W. Course, Philip A. Lewis, Sarah J. Kotecha, Michael Cousins, Kylie Hart, W. John Watkins, Kate J. Heesom, Sailesh Kotecha
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Despite evidence demonstrating persistent lung function deficits in preterm-born children, especially in those who had bronchopulmonary dysplasia (BPD) in infancy, the underlying biological mechanisms explaining these lung function deficits
Externí odkaz:
https://doaj.org/article/65bcf8964d564e0382bba338e7c561fd
Autor:
Sarah J. Kotecha, Christopher W. Course, Kathryn E. Jones, W. John Watkins, Janet Berrington, David Gillespie, Sailesh Kotecha
Publikováno v:
Trials, Vol 23, Iss 1, Pp 1-10 (2022)
Abstract Background Preterm birth, especially at less than 30 weeks’ gestation, is significantly associated with respiratory, neurodevelopmental and growth abnormalities. The AZTEC study has recruited 799 infants born at
Externí odkaz:
https://doaj.org/article/f0b799bc01574cf894f86fecea4b10f1
Autor:
Edward Parkinson, Federico Liberatore, W. John Watkins, Robert Andrews, Sarah Edkins, Julie Hibbert, Tobias Strunk, Andrew Currie, Peter Ghazal
Publikováno v:
Frontiers in Genetics, Vol 14 (2023)
Machine learning (ML) algorithms are powerful tools that are increasingly being used for sepsis biomarker discovery in RNA-Seq data. RNA-Seq datasets contain multiple sources and types of noise (operator, technical and non-systematic) that may bias M
Externí odkaz:
https://doaj.org/article/510c59cb6406405bb5a4ac1efbd65668
Autor:
Ella A. Kotecha, Lei Zhang, Ali Aboklaish, Michael Cousins, Kylie Hart, Sarah J. Kotecha, W. John Watkins, Sailesh Kotecha
Publikováno v:
PLoS ONE, Vol 18, Iss 11 (2023)
Externí odkaz:
https://doaj.org/article/3977bbcfba32437b9902e13dee16f1ff
Publikováno v:
Frontiers in Microbiology, Vol 10 (2019)
Molecular determinants underlying interferon (IFN)-macrophage biology can help delineate enzyme systems, pathways and mechanisms for enabling host-directed therapeutic approaches against infection. Notably, while the IFN antiviral response is known t
Externí odkaz:
https://doaj.org/article/d5cd8f0425b543a49cf8721f8b6cf87a
Autor:
Ho-Fung Chan, Laurie J. Smith, Alberto M. Biancardi, Jody Bray, Helen Marshall, Paul J. C. Hughes, Guilhem J. Collier, Madhwesha Rao, Graham Norquay, Andrew J. Swift, Kylie Hart, Michael Cousins, W. John Watkins, Jim M. Wild, Sailesh Kotecha
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 207:89-100