Zobrazeno 1 - 10
of 42
pro vyhledávání: '"W. J. van Oort"'
Autor:
W.E. van der Linden, S.J. Postma Kelder, M. Bos, J.J.M. Holthuis, Willem Verboom, J. Den Hartigh, W. J. van Oort, A. Hulshoff, David N. Reinhoudt, R.J. Driebergen
Publikováno v:
Analytica Chimica Acta. 233:251-268
The influence of methyl-, hydroxy and amino substituents on the electrochemical behaviour of simple 1,4-naphtho-and 1,4-benzoquinones, model compounds of many quinoid antitumour agents, in aqueous media was studied. Significant changes in electrochem
Publikováno v:
Analytica Chimica Acta. 174:71-82
An automatic, reliable, dynamic oxidative electrochemical detection system is described for on-line determination of electro-active compounds in effluents from high-performance liquid chromatographic systems. Detection can be done at constant potenti
Publikováno v:
Analytica Chimica Acta. 127:47-53
A high-performance liquid chromatographic method for the determination of the antitumor drug mitomycin C in blood plasma samples of cancer patients is described. The drug is extracted from the plasma with chloroform–2-propanol (1+1, ww) and chromat
Publikováno v:
International Journal of Pharmaceutics. 9:191-198
The dissociation of nalidixic acid in the near neutral pH region is shown to be due to a single prototropic equilibrium involving the carboxyl group exclusively. Precise dissociation constants as well as stability constants for the binding of the nal
Publikováno v:
Journal of Electroanalytical Chemistry and Interfacial Electrochemistry. 220:101-124
Oxidation of the anions of teniposide (I) and its aglycone (III) occurs over the pH range from 3 to 12 in two one-electron waves. The loss of the first electron yields a radical, the second a phenoxenium ion. The latter is converted by nucleophilic a
Publikováno v:
Analytica Chimica Acta. 111:275-279
The differential pulse polarographic determination of Corticosteroids in single-component tablets is described. The active compounds are extracted from the excipients with a solvent with similar lipophilicity as the polarographic solvents, with a yie
Publikováno v:
The Journal of Automatic Chemistry
It has been suggested that etoposide can be transformed ‘in vivo’ into a radical intermediate, which may be involved in the irreversible binding of etoposide to microsomal proteins and in DNA damage. To investigate some physico-chemical propertie
Publikováno v:
The Journal of Automatic Chemistry
An automatic, reliable, scanning reductive electrochemical detection system is described for on-line qualitative and semi-quantitative determination and characterization ofelectro-active compounds in effluentsfrom high-performance liquid chromatograp
Autor:
D. M. Barends, H. Lingeman, W. van der Doelen, W. M. J. Beek, H. J. Keukens, M. M. L. Aerts, J. H. Beijnen, R. J. Driebergen, T. J. M. Hodes, J. J. M. Holthuis, D. N. Reinhoudt, W. J. M. Underberg, A. Dams, G. de Groot, D. J. de Wildt, J. J. M. Lansemeyer, B. Sangster, L. Delbressine, M. Moonen, M. v. Oosterhout, G. Wagenaars, F. Kaspersen, M. De Smet, S. Van Belle, C. Storme, D. L. Massart, H. A. J. de Waal, J. C. Kraak, F. J. M. J. Haessen, S. M. Dreijer-van der Glas, A. Bult, B. F. H. Drenth, K. J. Hellingwerf, J. den Hartigh, J. S. Blauw, J. H. Beljnen, W. J. van Oort, S. J. Postma, W. Verboom, P. Lelieveid, R. H. Drost, R. D. van Ooijen, T. I. Ionescu, J. M. van Rossum, R. A. A. Maes, F. Elferink, W. J. F. van der Vijgh, I. Klein, H. M. Pinedo, N. Haagsma, B. Dieleman, B. G. M. Gortemaker, C. van de Water, M. J. B. Mengelers, C. Schreuder, A. Hulshoff, P. L. Jacobs, G. J. H. Scnmeits, H. Nieuwenhuyse, J. Vink, H. Jansen, E. G. van der Velde, U. A. Th. Brinkman, R. W. Frei, H. Veening, W. Th. Kok, W. H. Voogt, P. H. Kuijpers, J. Zeeman, G. J. de Jong, G. Musch, Frits A. J. Muskiet, N. M. M. Nibbering, H. J. E. M. Reeuwijk, U. R. Tjaden, L. G. C. Spanjers, J. P. de Kleijn, H. C. Kerkdijk, Gerrit L. M. van de Laar, Jan E. Paanakker, O. A. G. J. van der Houwen, J. Teeuwsen, J. v. Gorp, P. Salemink, M. Vermeulen, L. Kolkman, G. W. Welling, R. van der Zee, S. Wellinq-Wester, J. van der Greef
Publikováno v:
Pharmaceutisch Weekblad. 7:285-292
Publikováno v:
Journal of Electroanalytical Chemistry and Interfacial Electrochemistry. 184:317-329
The electrochemical oxidation of the antineoplastic agent etoposide in aqueous solution at a glassy carbon electrode shows an overall two electron transfer. At pH < 2.5, the oxidation proceeds in one voltammetric oxidation step. At pH ⩾ 2.5, the ox