Zobrazeno 1 - 10
of 182
pro vyhledávání: '"W. J. Smith"'
Autor:
Eleanor Star, Megan Stevens, Clare Gooding, Christopher W. J. Smith, Ling Li, Monica Lamici Ayine, Steve J. Harper, David O. Bates, Sebastian Oltean
Publikováno v:
Oncogenesis, Vol 10, Iss 5, Pp 1-12 (2021)
Abstract Alternative splicing of the vascular endothelial growth factor A (VEGF-A) terminal exon generates two protein families with differing functions. Pro-angiogenic VEGF-Axxxa isoforms are produced via selection of the proximal 3′ splice site o
Externí odkaz:
https://doaj.org/article/b2b9f454833f4965855002d89dcada06
Autor:
Vanessa D’Angeli, Elisa Monzón-Casanova, Louise S. Matheson, Özge Gizlenci, Georg Petkau, Clare Gooding, Rebecca V. Berrens, Christopher W. J. Smith, Martin Turner
Publikováno v:
European Journal of Immunology. 52:1058-1068
The RNA-binding protein polypyrimidine tract binding protein 1 (PTBP1) has been found to have roles in CD4 T-cell activation, but its function in CD8 T cells remains untested. We show it is dispensable for the development of naïve mouse CD8 T cells,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6177636ea190a0e34eb80d74763e8212
https://doi.org/10.1002/eji.202149781
https://doi.org/10.1002/eji.202149781
Autor:
Miren Agote-Arán, Anna B. Kroner, David S. Wragg, Wojciech A. Sławiński, Martha Briceno, Husn U. Islam, Igor V. Sazanovich, María E. Rivas, Andrew W. J. Smith, Paul Collier, Inés Lezcano-González, Andrew M. Beale
Publikováno v:
Molecules, Vol 25, Iss 21, p 5048 (2020)
Small pore zeolites have shown great potential in a number of catalytic reactions. While Mo-containing medium pore zeolites have been widely studied for methane dehydroaromatisation (MDA), the use of small pore supports has drawn limited attention du
Externí odkaz:
https://doaj.org/article/e9b03d6fc5eb44a7ad16bc406fd009e2
Phosphorylation of the smooth muscle master splicing regulator RBPMS regulates its splicing activity
Autor:
Michael D Barnhart, Yi Yang, Erick E Nakagaki-Silva, Thomas H Hammond, Mariavittoria Pizzinga, Clare Gooding, Katherine Stott, Christopher W J Smith
Funder: United States Air Force
We previously identified RBPMS as a master regulator of alternative splicing in differentiated smooth muscle cells (SMCs). RBPMS is transcriptionally downregulated during SMC dedifferentiation, but we hypothesized
We previously identified RBPMS as a master regulator of alternative splicing in differentiated smooth muscle cells (SMCs). RBPMS is transcriptionally downregulated during SMC dedifferentiation, but we hypothesized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1e02223f23a5669d61ef368c756705f
https://www.repository.cam.ac.uk/handle/1810/342090
https://www.repository.cam.ac.uk/handle/1810/342090
Autor:
Li Liu, Dmytro Kryvokhyzha, Catarina Rippe, Aishwarya Jacob, Andrea Borreguero-Muñoz, Karin G. Stenkula, Ola Hansson, Christopher W. J. Smith, Steven A. Fisher, Karl Swärd
Funder: Lund University
Differentiation of smooth muscle cells (SMCs) depends on serum response factor (SRF) and its co-activator myocardin (MYOCD). The role of MYOCD for the SMC program of gene transcription is well established. In contrast, th
Differentiation of smooth muscle cells (SMCs) depends on serum response factor (SRF) and its co-activator myocardin (MYOCD). The role of MYOCD for the SMC program of gene transcription is well established. In contrast, th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa58f53075d8b5591e2d2224fc687742
https://www.repository.cam.ac.uk/handle/1810/340334
https://www.repository.cam.ac.uk/handle/1810/340334
Publikováno v:
Nature reviews. Genetics. 23(11)
A major goal of evolutionary genetics is to understand the genetic processes that give rise to phenotypic diversity in multicellular organisms. Alternative splicing generates multiple transcripts from a single gene, enriching the diversity of protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bbb7bde84c818cdb80caf0fffeea05ff
https://pubmed.ncbi.nlm.nih.gov/35821097
https://pubmed.ncbi.nlm.nih.gov/35821097
Autor:
null Vanessa D'Angeli, null Elisa Monzón‐Casanova, null Louise S. Matheson, null Özge Gizlenci, null Georg Petkau, null Clare Gooding, null Rebecca V. Berrens, null Christopher W. J. Smith, null Martin Turner
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36b2140cf08aefb50350ca4671c26ca7
https://doi.org/10.1002/eji.202149781/v3/response1
https://doi.org/10.1002/eji.202149781/v3/response1
Autor:
Mojtaba Mollaei, Samuel W J Smith Bell, Ali Hosseini Rad S M, Joshua Colin Halpin, Alexander D. McLellan, Nattiya Hirankarn
Publikováno v:
Cancers
Cancers, Vol 13, Iss 1229, p 1229 (2021)
Cancers, Vol 13, Iss 1229, p 1229 (2021)
Simple Summary We review the mechanisms of cellular metabolism and mitochondrial function that have potential to impact on the success of chimeric antigen receptor (CAR) T cell therapy. The review focuses readers on mitochondrial functions to allow a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85ca095b141e6d07284ab39ef48e6eaf
https://pubmed.ncbi.nlm.nih.gov/33799768
https://pubmed.ncbi.nlm.nih.gov/33799768
Autor:
W. J. Smith
Publikováno v:
Pediatric Tumors: Immunological and Molecular Markers ISBN: 9781003068532
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af4902eb77a5b993f7d9fd68433d3f71
https://doi.org/10.4324/9781003068532-9
https://doi.org/10.4324/9781003068532-9