Zobrazeno 1 - 10 of 234 pro vyhledávání: '"W. J. Malaisse"'
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Site-Directed Mutations of the FAD-Linked Glycerophosphate Dehydrogenase Gene Impairs the Mitochondrial Anchoring of the Enzyme in Transfected COS-7 Cells
Autor: M E, Fabregat, E F, Usac, C, Franco, C, Enrich, W J, Malaisse, R, Gomis, C, Enric
Publikováno v: Biochemical and Biophysical Research Communications. 252:173-177
COS-7 cells were transfected with the green fluorescent protein (GFP) ofAequorea victoria,human mitochondrial FAD-linked glycerophosphate dehydrogenase (mGDH), a mGDHwt-EGFP construct, or two mutant mGDH-proteins fused with EGFP. The site of mutation
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::deebf3703c1543807dbf422bb3046b4e
https://doi.org/10.1006/bbrc.1998.9632
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6
[An ionic determination of the insulinotropic action of insulin: not everyone agrees]
Autor: W J, Malaisse
Publikováno v: Bulletin et memoires de l'Academie royale de medecine de Belgique. 163(1-2)
A recent model concerning the ionic determinants involved in the insulinotropic action of nutrients, namely an anion channel hypothesis, is presented, and selected experimental findings in support of such a model, are reviewed.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::cad44abf2102935cec13e0b0661a8b42
https://pubmed.ncbi.nlm.nih.gov/18819232
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7
Fate of3H- and14C-labelled A-4166 in pancreatic islets
Autor: W. J. Malaisse, F. Malaisse-Lagae
Publikováno v: Acta Diabetologica. 33:298-300
The fate of 3H- and 14C-labelled A-4166 was examined in rat pancreatic islets. The net uptake of the meglitinide analogue by islets incubated for 60 min in the presence of 0.1 mM A-4166 and then submitted to repeated washes was close to 0.1 pmol/isle
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f26bc32dfc29c1658a78c69635c88b85
https://doi.org/10.1007/bf00571569
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8
[Type I diabetes: an enteropathy?]
Autor: W J, Malaisse
Publikováno v: Bulletin et memoires de l'Academie royale de medecine de Belgique. 158(3-4)
In the animal model of type-1 diabetes found in BioBreeding rats, an enteropathy characterized by morphological, biochemical and functional features precedes the autoimmune insulitis, and both lesions are modulated in their severity by dietary factor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::10e253a954bc28d27fb4e39c883999a3
https://pubmed.ncbi.nlm.nih.gov/14639874
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9
Labelling of lipids by D-[1-14C]glucose, D-[6-14C] glucose and D-[3-3H]glucose in pancreatic islets from normal and GK rats
Autor: H X, Zhang, H, Jijakli, P, Courtois, A, Sener, W J, Malaisse
Publikováno v: Molecular and cellular biochemistry. 252(1-2)
In pancreatic islets prepared from either normal or GK rats and incubated at either low (2.8 mM) or high (16.7 mM) D-glucose concentration, the labelling of both lipids and their glycerol moiety is higher in the presence of D-[1-14C]glucose than D-[6
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::47d217d9d27d23856b578f0ffe7b1cd9
https://pubmed.ncbi.nlm.nih.gov/14577599
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10
[Meglitinide analogs: new insulinotropic agents for the treatment of non-insulin dependent diabetes]
Autor: W J, Malaisse
Publikováno v: Revue medicale de Bruxelles. 24(3)
In 1995, several new molecules under study as potential insulinotropic agents for the treatment of non-insulindependent diabetes mellitus were identified as analogs of meglitinide, previously known as the non-sulfonylurea moiety of glibenclamide. Thr
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bfd114e672a4b8520633028d000134d5
https://pubmed.ncbi.nlm.nih.gov/12891883
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