Zobrazeno 1 - 5
of 5
pro vyhledávání: '"W. J. M. Jansen"'
Autor:
Marc A. Kedde, H.M. Pinedo, W. J. M. Jansen, W.J.F. van der Vijgh, Epie Boven, J. van Ark-Otte, G. Giaccone, A.-M. C. Dingemans
Publikováno v:
British Journal of Cancer
Scopus-Elsevier
Scopus-Elsevier
Irinotecan (CPT-11) is a semisynthetic camptothecin derivative with a broad spectrum of anti-tumour activity. Carboxylesterase (CE) catalyses the conversion of CPT-11 to SN-38 (7-ethyl-10-hydroxycamptothecin), the active form of CPT-11. The antiproli
Publikováno v:
Boven, E, Jansen, W J M, Hulscher, T M, Beijnen, J H & van Tellingen, O 1999, ' The influence of P170-glycoprotein on the efficacy and distribution of vincristine as well as on MDR1 expression in BRO/mdr1.1 human melanoma xenografts ', European Journal of Cancer, vol. 35, pp. 840-849 . https://doi.org/10.1016/S0959-8049(99)00013-1
European Journal of Cancer, 35, 840-849. Pergamon
European Journal of Cancer, 35, 840-849. Pergamon
Multidrug resistance modulators may increase the antitumour efficacy of drugs affected by P170-glycoprotein (Pgp) in Pgp-positive tumours in vivo . Inhibition of Pgp function in normal tissues, however, may enhance side-effects. Dexniguldipine-HCl, i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cab186d922f1d04879e17b247cf7644
https://research.vumc.nl/en/publications/79c191a6-839a-48c7-a707-e5fd0447d665
https://research.vumc.nl/en/publications/79c191a6-839a-48c7-a707-e5fd0447d665
Autor:
J. van Ark-Otte, C. A. M. Erkelens, W. J. M. Jansen, G. M. Kolfschoten, H.M. Pinedo, Epie Boven
Publikováno v:
International Journal of Cancer, 73, 891-896. Wiley-Liss Inc.
Jansen, W J M, Kolfschoten, G M, Erkelens, C A M, van Ark-Otte, J, Pinedo, H M & Boven, E 1997, ' Antitumor activtiy of CPT-11 in experimental human ovarian cancer and soft-tissue sarcoma ', International Journal of Cancer, vol. 73, pp. 891-896 . https://doi.org/10.1002/(SICI)1097-0215(19971210)73:6<891::AID-IJC22>3.0.CO;2-6
Jansen, W J M, Kolfschoten, G M, Erkelens, C A M, van Ark-Otte, J, Pinedo, H M & Boven, E 1997, ' Antitumor activtiy of CPT-11 in experimental human ovarian cancer and soft-tissue sarcoma ', International Journal of Cancer, vol. 73, pp. 891-896 . https://doi.org/10.1002/(SICI)1097-0215(19971210)73:6<891::AID-IJC22>3.0.CO;2-6
CPT-11, a semi-synthetic derivative of camptothecin, was investigated for its activity in panels of 15 human ovarian-cancer lines and 10 human soft-tissue sarcoma lines grown s.c. in nude mice. Various factors were analyzed that may be of influence o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9d8b16babd490d748c409f2ba78aa29
https://research.vumc.nl/en/publications/6a62de0b-4f72-46fe-9bbf-61127d9878d5
https://research.vumc.nl/en/publications/6a62de0b-4f72-46fe-9bbf-61127d9878d5
Publikováno v:
European journal of cancer (Oxford, England : 1990). (13-14)
Dipyridamole is known as a potent inhibitor of facilitated diffusion-mediated nucleoside transport as well as a modulator of ‘classical' multidrug resistance. BIBW22BS, a derivative of dipyridamole, has been found to be 20-to 100-fold more potent i
Publikováno v:
Scopus-Elsevier
British Journal of Cancer
British Journal of Cancer
The relevance of P170-glycoprotein (P-gp) and multidrug resistance-associated protein (MRP) for the sensitivity to CPT-11 was investigated in human malignant cell lines as well as in human tumour xenografts. In vitro, the P-gp-positive sublines BRO/m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c28ee3980166c1647f5f6b8639a5a96
http://www.scopus.com/inward/record.url?eid=2-s2.0-0031962772&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-0031962772&partnerID=MN8TOARS