Zobrazeno 1 - 10
of 37
pro vyhledávání: '"W. J. Habets"'
Autor:
W. J. Habets, Walther J. van Venrooij, Volker Heinrichs, Frank Simons, Reinhard L€hrmann, Rob L.H. Nelissen
Publikováno v:
Nucleic Acids Research. 19:449-454
The U1 small nuclear ribonucleoprotein (snRNP) contains three specific proteins denoted 70K, A and C, in addition to the common proteins. Specific functions of these proteins are not known although recently protein C was shown to be involved in the b
Autor:
A Richter, F.H.J. van den Hoogen, Ria P. Beijer, W. J. Habets, W. J. Van Venrooij, E. Penner, R. Verheijen
Publikováno v:
Clinical and Experimental Immunology. 80:38-43
SUMMARY We report the expression of a cDNA clone encoding 695 carboxyl-terminal amino acids of human DNA topoisomerase I (topoI) in Escherichia coli. More than 96% of the anti-HeLa topoI-positive sera from patients with a connective tissue disease di
Publikováno v:
European Journal of Immunology. 20:437-440
The nucleoplasmic U small nuclear ribonucleoprotein particles (snRNP) have a set of seven proteins in common which are designated B', B, D, D', E, F and G. Patients suffering from rheumatoid autoimmune diseases such as systemic lupus erythematosus of
Autor:
Gopa Raychaudhuri, Ann L. Beyer, Adrian R. Krainer, Sally A. Amero, C L Cass, W. J. Van Venrooij, W J Habets
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 89(18)
The major nuclear ribonucleoproteins (RNPs) involved in pre-mRNA processing are classified in broad terms either as small nuclear RNPs (snRNPs), which are major participants in the splicing reaction, or heterogeneous nuclear RNPs (hnRNPs), which trad
Autor:
F.H.J. van den Hoogen, T. M. Meesters, M. H. Hoet, W. J. Habets, R. Verheijen, W. J. Van Venrooij
Publikováno v:
Molecular biology reports. 16(2)
In this paper an immunodominant epitope of Topoisomerase I is described. An epitope expression sublibrary was constructed from Topoisomerase I cDNA. The subclones were screened with an antiserum from a patient with systemic sclerosis (SSc). The posit
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
instname
instname
The organization of the UlsnRNP-specific A protein (34 kDa) has been analyzed by 12 and 16 Å thiol-reversible chemical cross-linking and Western blotting. A-containing cross-linked complexes had molecular masses of 43, 47, 56, 62, 67, 105 and 125 kD
Autor:
W. J. Van Venrooij, L. B. A. Van De Putte, D. J. De Rooij, W. J. Habets, A. L. Verbeek, M. H. Hoet
Publikováno v:
Annals of the rheumatic diseases. 49(6)
In a three year prospective study disease activity variables and levels of antibody against the RNP-peptides 70K and A were measured in 18 patients with mixed connective tissue disease. Antibody measurement entailed use of cloned autoantigens in an e
Publikováno v:
Arthritis and rheumatism. 33(6)
Autoantibodies against small nuclear ribonucleoproteins (snRNP) are common in systemic lupus erythematosus and related disorders. The 3 categories, anti-(U1)RNP, anti-(U1, U2)RNP, and anti-Sm, all contain a common antibody specificity directed agains
Autor:
W. J. Van Venrooij, M. H. Hoet, W. J. Habets, P. T. G. Sillekens, M. R. Lerner, G. Mcallister
Publikováno v:
Proceedings of the National Academy of Sciences. 86:4674-4678
Autoantibodies from a patient with systemic lupus erythematosus, which recognize U1 and U2 small nuclear ribonucleoprotein particles (snRNPs), were used to map B-cell autoepitopes on the U1 snRNP-specific A protein. This protein contains two regions
Autor:
L. B. A. Van De Putte, D. J. R. A. M. De Rooij, W. J. Habets, W. J. Van Venrooij, S. O. Stapel
Publikováno v:
Scandinavian Journal of Rheumatology. 14:93-97