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Autor:
Steven Nasioulas, W. J. H. Scott, Finlay A. Macrae, E. Edkins, R. J. M. Gardner, D A Kool, I. R. Walpole
Publikováno v:
Gastroenterology. 113(1)
Familial adenomatous polyposis (FAP) is caused by mutations in the adenomatous polyposis coli (APC) gene, and different mutations may produce different clinical pictures. Most mutations occur in the 5' half of the gene, and mutations toward the 3' en