Zobrazeno 1 - 10
of 27
pro vyhledávání: '"W. J. Arendshorst"'
Publikováno v:
American Journal of Physiology-Renal Physiology. 270:F749-F755
The purpose of the present study was to determine the role of endogenous angiotensin II in exaggerated tubuloglomerular feedback (TGF) in young euvolemic spontaneously hypertensive rats (SHR). TGF was characterized by measuring proximal tubular stop-
Autor:
C. Chatziantoniou, W. J. Arendshorst
Publikováno v:
American Journal of Physiology-Renal Physiology. 262:F68-F76
The objective of this study was to investigate the ability of the vasodilator prostaglandins E2 (PGE2) and I2 (PGI2) to interact with the vasoconstrictor action of angiotensin II (ANG II), norepinephrine (NE), and thromboxane A2 (TxA2) in the renal v
Autor:
W. J. Arendshorst, C. Chatziantoniou
Publikováno v:
American Journal of Physiology-Renal Physiology. 262:F124-F130
The objective of this study was to test the hypothesis that the vasodilator prostaglandins E2 (PGE2) and PGI2) participate in the mechanisms involved in the increased renal vascular reactivity (RVR) observed in genetic hypertension. Studies were perf
Publikováno v:
American Journal of Physiology-Renal Physiology. 259:F372-F382
The objective of this study was to test the hypothesis that angiotensin II and thromboxane A2 (TxA2) contribute to the elevated renal vascular resistance observed during the development of genetic hypertension. In 6-wk-old anesthetized spontaneously
Autor:
B M, Iversen, W J, Arendshorst
Publikováno v:
Journal of the American Society of Nephrology : JASN. 10
Experiments were conducted to gain insight into calcium signaling mechanisms triggered by angiotensin II (AngII) stimulation in vascular smooth muscle cells (SMC) freshly isolated from preglomerular vessels of normotensive Wistar Kyoto rats (WKY) and
Publikováno v:
Journal of the American Society of Nephrology : JASN. 10
Angiotensin II (AngII) exerts powerful effects on the renal microcirculation to influence a variety of functions. This review summarizes some of the major findings over the past 10 years as they elucidate the multiple roles that AngII plays in the re
Publikováno v:
Journal of the American Society of Nephrology : JASN. 10
This study examines the effect of systemic blockade of angiotensin II AT1 receptors by candesartan on the exaggerated tubuloglomerular feedback (TGF) activity in 7-wk-old, euvolemic spontaneously hypertensive rats (SHR) and in Wistar-Kyoto rats (WKY)
Publikováno v:
Journal of the American Society of Nephrology : JASN. 10
This study determined the inhibitory effect of the angiotensin II (AngII) type I (AT1) receptor blocker candesartan on renal vascular reactivity in vivo. Reactivity to AngII before and during candesartan administration was assessed by measuring (by e
Publikováno v:
Kidney international. Supplement. 30
Studies have examined renal function to determine the role of the kidney in the pathogenesis and maintenance phases of hypertension in the Okamoto-Aoki strain of spontaneously hypertensive rat (SHR). As compared to age-matched Wistar-Kyoto rats (WKY)
Publikováno v:
The American journal of physiology. 259(3 Pt 2)
The steady-state behavior of the tubuloglomerular feedback system has been studied in detail, but little is known about its dynamics. However, kinetic data can provide insight regarding the contribution of feedback to autoregulatory responses. Accord