Výsledky vyhledávání - "W. Hunter White"

Evaluation of an 11.2% spinetoram topical spot-on solution for the control of experimental and natural flea (Ctenocephalides felis) infestations on cats in Europe

Autor: Candace M. Trout, David W. Wheeler, Joseph Raymond Winkle, Caryn M. Thompson, W. Hunter White

Publikováno v: Veterinary parasitology. 258

Spinetoram is the newest member the spinosyn-class of natural products to be commercialized for flea control on cats in the United States under the tradename Cheristin® for cats. This report describes results from two laboratory studies and a multi-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2762e25c955a4f59b070e045023309f
https://pubmed.ncbi.nlm.nih.gov/30105986

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Discovery of an orally bioavailable isoxazoline benzoxaborole ( AN8030 ) as a long acting animal ectoparasiticide

Autor: Yasheen Zhou, Defauw Jean Marie, Terry William Balko, Eric E. Easom, Wuxin Zou, Jianxin Cao, Tsutomu Akama, Yong-Kang Zhang, Joseph Raymond Winkle, Jian Xue, Wei Bu, Jacob J. Plattner, Shenghai Guo, W. Hunter White

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 25:5589-5593

A novel series of isoxazoline benzoxaborole small molecules was designed and synthesized for a structure-activity relationship (SAR) investigation to assess the ectoparasiticide activity against ticks and fleas. The study identified an orally bioavai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d92604251fefa4eb6bb096549743d41
https://doi.org/10.1016/j.bmcl.2015.10.044

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Initial evaluations of the effectiveness of spinetoram as a long-acting, oral systemic pulicide for controlling cat flea (Ctenocephalides felis) infestations on dogs

Autor: Kari Lynette Riggs, Daniel E. Snyder, David R. Young, Michelle Leigh Totten, W. Hunter White, Christine M. McCoy

Publikováno v: Veterinary parasitology. 233

Spinetoram is a semi-synthetic, spinosyn class natural product derived from fermentation by the actinomycete, Saccharopolyspora spinosa. Based on LD50 (50% lethal dose) values against adult cat fleas (Ctenocephalides felis) using an in vitro contact

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3ba505d80b76d99ceacc25082b9bcbb
https://pubmed.ncbi.nlm.nih.gov/28043384

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Optimization of isoxazoline amide benzoxaboroles for identification of a development candidate as an oral long acting animal ectoparasiticide

Autor: Jianzhang Yang, Joseph Raymond Winkle, Jacob J. Plattner, Yong-Kang Zhang, Zhixin Ge, Eric E. Easom, Jianxin Cao, Terry William Balko, Yasheen Zhou, Defauw Jean Marie, W. Hunter White, Tsutomu Akama

Publikováno v: Bioorganicmedicinal chemistry letters. 26(13)

Novel isoxazoline amide benzoxaboroles were designed and synthesized to optimize the ectoparasiticide activity of this chemistry series against ticks and fleas. The study identified an orally bioavailable molecule, (S)-N-((1-hydroxy-3,3-dimethyl-1,3-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e5faf93f91bfd392cc2d3f56f43e76a
https://pubmed.ncbi.nlm.nih.gov/27210432

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Efficacy of Spinosad Against Acaricide-Resistant and -Susceptible Rhipicephalus (Boophilus) microplus and Acaricide-Susceptible Amblyomma americanum and Dermacentor variabilis

Autor: Adalberto A. Pérez de León, W. Hunter White, Ronald B. Davey, John E. George, Robert J. Miller

Publikováno v: Journal of Medical Entomology. 48:358-365

Various acaricide-resistant strains of Rhipicephalus (Boophilus) microplus, representative of the major resistance mechanisms found in Mexico and Brazil, were exposed to spinosad using the Food and Agriculture Organization of the United Nations larva

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe60260b4938742672a49ebc9a5abafb
https://doi.org/10.1603/me08222

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A Comparison of Three Bioassay Techniques to Determine Amitraz Susceptibility in Boophilus microplus (Acari: Ixodidae)

Autor: Robert J. Miller, Ronald B. Davey, W. Hunter White, John E. George

Publikováno v: Journal of Medical Entomology. 44:283-294

The ability of the Miller, Soberanes, and White bioassay techniques to describe amitraz susceptibility in three different strains of Boophilus microplus (Canestrini) (Acari: Ixodidae) was compared. For a susceptible strain, all techniques adequately

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::78d9b7a69316c535977b35ded41817e3
https://doi.org/10.1603/0022-2585(2007)44[283:acotbt]2.0.co

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Comparison of In Vitro and In Vivo Ectoparasiticide Activity of Experimental Benzimidazole-Carbamate with Permethrin and Amitraz

Autor: Xiaowen Zhao, Steven M. Bauer, Jesus A. Gutierrez, W. Hunter White, Charles K. Smith

Publikováno v: Journal of Medical Entomology. 42:207-211

A series of in vitro and in vivo bioassays were conducted to assess the ectoparasiticide activity of isopropyl-4-nitro-2,6-bis(trifluoromethyl)-1-benzimidazole-carbamate, an experimental benzimidazole-carbamate class compound. This compound was less

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::609b629c299b2627a115efe4dcf2034c
https://doi.org/10.1093/jmedent/42.2.207

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