Zobrazeno 1 - 10
of 619
pro vyhledávání: '"W. Hooper"'
Autor:
Rebecca L. Brocato, Hua Wu, Steven A. Kwilas, Lucia M. Principe, Matthew Josleyn, Joshua Shamblin, Padmanabh Chivukula, Christoph Bausch, Thomas Luke, Eddie J. Sullivan, Jay W. Hooper
Publikováno v:
mBio, Vol 15, Iss 10 (2024)
ABSTRACT Hantaviruses are rodent-borne viruses that cause severe disease in infected humans. In the New World, major hantaviruses include Andes virus (ANDV) and Sin Nombre virus (SNV) causing hantavirus pulmonary syndrome. In the Old World, major han
Externí odkaz:
https://doaj.org/article/01710f5a81a041a5bbfa4da83d44770e
Publikováno v:
Vaccines, Vol 12, Iss 6, p 674 (2024)
Convalescent plasma has been shown to be effective at protecting humans against severe diseases caused by New World (NW) arenaviruses, including Junin virus (JUNV) and Machupo virus (MACV). This plasma contains antibodies against the full complement
Externí odkaz:
https://doaj.org/article/256ecf045e2f4bedb180e775deb6b634
Autor:
Julie A. Ake, Kristopher Paolino, Jack N. Hutter, Susan Biggs Cicatelli, Leigh Anne Eller, Michael A. Eller, Margaret C. Costanzo, Dominic Paquin-Proulx, Merlin L. Robb, Chi L. Tran, Lalaine Anova, Linda L. Jagodzinski, Lucy A. Ward, Nicole Kilgore, Janice Rusnak, Callie Bounds, Christopher S. Badorrek, Jay W. Hooper, Steven A. Kwilas, Ine Ilsbroux, Dickson Nkafu Anumendem, Auguste Gaddah, Georgi Shukarev, Viki Bockstal, Kerstin Luhn, Macaya Douoguih, Cynthia Robinson
Publikováno v:
Vaccines, Vol 12, Iss 5, p 497 (2024)
The safety and immunogenicity of the two-dose Ebola vaccine regimen MVA-BN-Filo, Ad26.ZEBOV, 14 days apart, was evaluated in people without HIV (PWOH) and living with HIV (PLWH). In this observer-blind, placebo-controlled, phase 2 trial, healthy adul
Externí odkaz:
https://doaj.org/article/d508ae26d5664c20827179054ade0b7e
Autor:
Ian Davis, Jackie M. Payne, Victoria L. Olguin, Madison P. Sanders, Tamara Clements, Christopher P. Stefan, Janice A. Williams, Jay W. Hooper, John W. Huggins, Eric M. Mucker, Keersten M. Ricks
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
Human monkeypox (mpox) has recently become a global public health emergency; however, assays that detect mpox infection are not widely available, largely due to cross-reactivity within the Orthopoxvirus genus. Immunoassay development was largely conf
Externí odkaz:
https://doaj.org/article/62617241fc5e442ca113e2ef5c893fef
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 28, Iss , Pp 847-858 (2022)
Poxviruses are a large and complex family of viruses with members such as monkeypox virus and variola virus. The possibility of an outbreak of monkeypox virus (or a related poxvirus) or the misuse of variola virus justifies the development of counter
Externí odkaz:
https://doaj.org/article/eab0acecfcea4c89975eb47a9a6c4539
Autor:
Taylor B Engdahl, Elad Binshtein, Rebecca L Brocato, Natalia A Kuzmina, Lucia M Principe, Steven A Kwilas, Robert K Kim, Nathaniel S Chapman, Monique S Porter, Pablo Guardado-Calvo, Félix A Rey, Laura S Handal, Summer M Diaz, Irene A Zagol-Ikapitte, Minh H Tran, W Hayes McDonald, Jens Meiler, Joseph X Reidy, Andrew Trivette, Alexander Bukreyev, Jay W Hooper, James E Crowe
Publikováno v:
eLife, Vol 12 (2023)
Hantaviruses are high-priority emerging pathogens carried by rodents and transmitted to humans by aerosolized excreta or, in rare cases, person-to-person contact. While infections in humans are relatively rare, mortality rates range from 1 to 40% dep
Externí odkaz:
https://doaj.org/article/8473aa7cf9fd4f6f8543805191bc6878
Autor:
Grayson W. Hooper, Daniel T. Ginat
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
MRI plays an important role in the evaluation of glioblastoma, both at initial diagnosis and follow up after treatment. Quantitative analysis via radiomics can augment the interpretation of MRI in terms of providing insights regarding the differentia
Externí odkaz:
https://doaj.org/article/f668fa2effcf467db296157c8aee8e0f
Autor:
John J. Suschak, Sandra L. Bixler, Catherine V. Badger, Kristin W. Spik, Steven A. Kwilas, Franco D. Rossi, Nancy Twenhafel, Melissa L. Adams, Charles J. Shoemaker, Erin Spiegel, Jay W. Hooper
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-11 (2022)
Abstract We have previously shown that DNA vaccines expressing codon optimized alphavirus envelope glycoprotein genes protect both mice and nonhuman primates from viral challenge when delivered by particle-mediated epidermal delivery (PMED) or intram
Externí odkaz:
https://doaj.org/article/f92e042439674e0e833a0ec86aaa0fb7
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0275082 (2023)
A SARS-CoV-2 DNA vaccine targeting the spike protein and delivered by jet injection, nCOV-S(JET), previously shown to protect wild-type and immunosuppressed Syrian hamsters (Mesocricetus auratus), was evaluated via two needle-free delivery methods in
Externí odkaz:
https://doaj.org/article/f72ecf297ca74b66bd46b9b561552134
Autor:
Yun Ji, Qi Zhang, Lin Cheng, Jiwan Ge, Ruoke Wang, Mengqi Fang, Eric M. Mucker, Peng Chen, Ji Ma, Rui Zhang, Chunming Li, Holly Hammond, Lauren Baracco, Michael Holbrook, Matthew Frieman, Zheng Zhang, Xinquan Wang, Jay W. Hooper, Linqi Zhang, Qing Zhu
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Monoclonal antibodies (mAbs) targeting the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein have demonstrated clinical efficacy in preventing or treating coronavirus disease 2019 (COVID-19), resulting in the emergency use au
Externí odkaz:
https://doaj.org/article/c44757fcc73249619c8e0e342192a10c