Zobrazeno 1 - 7
of 7
pro vyhledávání: '"W. Henning Boehncke"'
Autor:
Gertie J. Oostingh, Miroslava Pozgajova, Ralf J. Ludwig, Thomas Krahn, W.-Henning Boehncke, Bernhard Nieswandt, Michael P. Schön
Publikováno v:
Haematologica, Vol 92, Iss 4 (2007)
Background and Objectives P-selectin has been implicated in important platelet functions. However, neither its role in thrombus formation and cardiovascular disorders nor its suitability as a therapeutic target structure is entirely clear.Design and
Externí odkaz:
https://doaj.org/article/71b2bee76b6843bdab6f39686c75258e
Autor:
Christoph M. Schempp, Heike Beschmann, Walter E. Müller, Kerstin Hill, Maik Gollasch, Kirill Essin, Christian Harteneck, Kristina Leuner, Margarethe Müller, W. Henning Boehncke, Simone A. Rubant
Publikováno v:
Journal of Biological Chemistry, Vol. 283, No 49 (2008) pp. 33942-33954
The protective epithelial barrier in our skin undergoes constant regulation, whereby the balance between differentiation and proliferation of keratinocytes plays a major role. Impaired keratinocyte differentiation and proliferation are key elements i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3398613d92a8e4c81b27488fb80fbb7f
https://doi.org/10.1074/jbc.m801844200
https://doi.org/10.1074/jbc.m801844200
Autor:
Michael P. Schön, W.-Henning Boehncke
Publikováno v:
New England Journal of Medicine, Vol. 352, No 18 (2005) pp. 1899-1912
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f5fa9ca5a0a5834454d3186216cbe75
https://doi.org/10.1056/nejmra041320
https://doi.org/10.1056/nejmra041320
Autor:
Liliane Chatenoud, Luigi Naldi, Michael P. Schön, Miguel G. Madariaga, Sujoy Khan, W. Henning Boehncke
Publikováno v:
New England Journal of Medicine. 353:848-850
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d019362abdd6528f833c95d3d38da62
https://doi.org/10.1056/nejmc051541
https://doi.org/10.1056/nejmc051541
Autor:
Bernd Kramer, Maria L. Rodriguez, Michael P. Schön, B. Gregor Wienrich, Thomas Krahn, W. Henning Boehncke, Margarete Schön, Matthias Busemann
Publikováno v:
Journal of Investigative Dermatology, Vol. 126, No 4 (2006) pp. 882-889
Selectin-mediated leukocyte adhesion to endothelia, the crucial first step initiating the pathogenic cascade of inflammation, is an attractive target for specific therapies. The small-molecule macrolide, efomycine M, inhibits selectin-mediated leukoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54dd98123988bde6d7bf99a7483bd13b
https://archive-ouverte.unige.ch/unige:29751
https://archive-ouverte.unige.ch/unige:29751
Autor:
Gesche Harms, Sven Enders, Ralf Ludwig, Michael P. Schön, Bernd Kramer, Gertie J. Oostingh, B. Gregor Wienrich, Rudolf Tauber, W. Henning Boehncke, Thomas Krahn
Publikováno v:
Nature Medicine. 12:873-874
The hypothesis raised by von Bonin et al. is an interesting extension of our previous findings. However, the single previously known hydrogen bond within the efomycine molecule does not exclude the pharmacophore hypothesis, and the use of artificial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e18520e2f9b32eed1c2bea41e7de73ab
https://doi.org/10.1038/nm0806-873b
https://doi.org/10.1038/nm0806-873b
Autor:
Gesche Harms, W. Henning Boehncke, Michael P. Schön, Sabine Grüner, Ralf Ludwig, Bernhard Nieswandt, Gertie J. Oostingh, Sven Enders, Rudolf Tauber
Publikováno v:
Journal of Investigative Dermatology, Vol. 127, No 1 (2007) pp. 90-97
Selectins are attractive targets for specific anti-inflammatory therapies. Using human lymphocytes as well as an L-selectin-transfected pre-B-cell line in dynamic flow chamber experiments, we could demonstrate that the small-molecule compound efomyci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba21d0ac948d63a9630d9de5bc9428fe