Zobrazeno 1 - 10
of 1 073
pro vyhledávání: '"W. Hein"'
Autor:
Mark A. Doll, David W. Hein
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Human arylamine N-acetyltransferase 1 (NAT1) catalyzes the N-acetylation of arylamine carcinogens such as 4-aminobiphenyl (ABP), and following N-hydroxylation, the O-acetylation of N-hydroxy-arylamine carcinogens such as N-hydroxy-ABP (N-OH-ABP). Gen
Externí odkaz:
https://doaj.org/article/1dad4adfa9a94106ba20a3a34b3ae2a3
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Arylamine N-acetyltransferases catalyze the transfer of acetyl groups from the endogenous cofactor acetyl coenzyme A (AcCoA) to arylamine (N-acetylation) and N-hydroxy-arylamine (O-acetylation) acceptors. Humans express two arylamine N-acetyltransfer
Externí odkaz:
https://doaj.org/article/d6d64a673dec48abb8bd7014749e6a31
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Many cancers, including breast cancer, have shown differential expression of human arylamine N-acetyltransferase 1 (NAT1). The exact effect this differential expression has on disease risk and progression remains unclear. While NAT1 is classically de
Externí odkaz:
https://doaj.org/article/91849fe6df60449a9708d1dbab6f9805
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Arylamine N-acetyltransferase 1 (NAT1) is a drug metabolizing enzyme that influences cancer cell proliferation and survival, especially in breast cancer. Lysine-acetylation is an important Post-Translational Modification (PTM) in the regulation of di
Externí odkaz:
https://doaj.org/article/5be93f7bb87b46d9a37cb535763503f8
Autor:
Wankun Xie, Min Zhao, Shu-Huai Tsai, William L. Burkes, Luke B. Potts, Wenjuan Xu, H. Ross Payne, Travis W. Hein, Lih Kuo, Robert H. Rosa, Jr.
Publikováno v:
Data in Brief, Vol 21, Iss , Pp 1019-1025 (2018)
The data presented in this article are related to the research paper entitled “Correlation of Spectral Domain Optical Coherence Tomography with Histology and Electron Microscopy in the Porcine Retina” (Xie et al., 2018) [2]. This research data hi
Externí odkaz:
https://doaj.org/article/63608a688e4042b89016ed84c1815261
Publikováno v:
Archives of Toxicology. 97:1773-1781
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::64e20b501546d5fb100d12832e1009b2
https://doi.org/10.1007/s00204-023-03508-1
https://doi.org/10.1007/s00204-023-03508-1
Autor:
Mariam R. Habil, David W. Hein
Publikováno v:
Archives of Toxicology. 97:1765-1772
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::487380cc0a493576b57205940e0b9942
https://doi.org/10.1007/s00204-023-03497-1
https://doi.org/10.1007/s00204-023-03497-1
Publikováno v:
Archives of Toxicology. 97:1613-1626
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a3e602077e87803eebaefb237a49461
https://doi.org/10.1007/s00204-023-03488-2
https://doi.org/10.1007/s00204-023-03488-2
Publikováno v:
Toxicological Sciences. 190:158-172
Arylamine N-acetyltransferase 2 (NAT2) is well-known for its role in phase II metabolism of xenobiotics and drugs. More recently, genome wide association studies and murine models implicated NAT2 in regulation of insulin sensitivity and plasma lipid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1afcac386e43169620159aa291052acb
https://doi.org/10.1093/toxsci/kfac103
https://doi.org/10.1093/toxsci/kfac103
Publikováno v:
Archives of Toxicology. 97:189-199
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1d31e798db2e8070ae2a1837fe05407
https://doi.org/10.1007/s00204-022-03383-2
https://doi.org/10.1007/s00204-022-03383-2