Zobrazeno 1 - 9
of 9
pro vyhledávání: '"W. H. McLaughlin"'
Autor:
Michael W. Epperly, William D. Bloomer, K.M.R. Pillai, W. H. McLaughlin, Kalyani M. Damodaran
Publikováno v:
The Journal of Steroid Biochemistry and Molecular Biology. 39:729-734
Therapeutic strategies for human breast cancer using 125I-labeled steroid hormones are clinically attractive in light of the estrogen dependence of many human breast cancers and the favorable microdosimetry resulting from 125I decay. We determined th
Autor:
W. H. McLaughlin, D.E. Seitz, Ralph R. Weichselbaum, Stephen Adelstein, William D. Bloomer, Robert N. Hanson
Publikováno v:
Journal of Radioanalytical Chemistry. 65:209-221
There is abundant evidence that Auger effects from125I are singularly damaging if localized within DNA as the thymidine analogue125I-iododeoxyuridine (125IUdR). Recent work with125I-labeled intercalating agents and steroid sex hormones extends these
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 8:1903-1908
The biological consequences of differential subcellular radionuclide accumulation within nuclear structures have important implications for the design and development of new therapeutic agents for cancer management. A growing body of experimental dat
Publikováno v:
Journal of cellular biochemistry. 21(1)
Auger effects from 125I decay are singularly damaging if localized in DNA as the thymidine analogue 125I-iododeoxyuridine (125IUdR). Recent experience with steroid sex hormones extends these observations by demonstrating cytotoxicity in sites other t
Autor:
T.J. Ruth, PR Gordon, Stephen Adelstein, W. H. McLaughlin, R.D. Neirinckx, A.P. Wolf, William D. Bloomer
Publikováno v:
Science (New York, N.Y.). 212(4492)
An investigation of the efficacy of astatine-211--tellurium colloid for the treatment of experimental malignant ascites in mice reveals that this alpha-emitting radiocolloid can be curative without causing undue toxicity to normal tissue. By comparis
Publikováno v:
Radiation research. 70(2)
Autor:
D.E. Seitz, Ralph R. Weichselbaum, G.L. Tonnesen, William D. Bloomer, John Nove, Samuel Hellman, W. H. McLaughlin, John B. Little, A.L. Rosner, Stephen Adelstein, N.A. Burstein, Robert N. Hanson
Publikováno v:
International journal of radiation biology and related studies in physics, chemistry, and medicine. 38(2)
Autor:
K. M. R. Pillai, W. H. McLaughlin, J. P. Edasery, R. A. Milius, R. D. Blumenthal, William D. Bloomer
Publikováno v:
Journal of the National Cancer Institute. 81(6)
Therapeutic strategies using 125I-labeled steroid hormones are attractive in light of the estrogen dependence of many human breast cancers and the favorable microdosimetry resulting from 125I decay. We determined the uptake, specific estrogen recepto
Publikováno v:
Strahlentherapie. 160(12)