Zobrazeno 1 - 10
of 75
pro vyhledávání: '"W. H. Fleming"'
Autor:
J. McClatchy, R. Strogantsev, E. Wolfe, H. Y. Lin, M. Mohammadhosseini, B. A. Davis, C. Eden, D. Goldman, W. H. Fleming, P. Conley, G. Wu, L. Cimmino, H. Mohammed, A. Agarwal
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Clonal hematopoiesis (CH) is defined as a single hematopoietic stem/progenitor cell (HSPC) gaining selective advantage over a broader range of HSPCs. When linked to somatic mutations in myeloid malignancy-associated genes, such as TET2-media
Externí odkaz:
https://doaj.org/article/46073c65efef47319cd7fee492ddc3b3
Publikováno v:
Blood. 83:3758-3779
Hematopoietic stem cells (HSCs) are believed to play a critical role in the sustained repopulation of all blood cells after bone marrow transplantation (BMT). However, understanding the role of HSCs versus other hematopoietic cells in the quantitativ
Publikováno v:
The Laryngoscope. 57(3)
Publikováno v:
Experimental hematology. 29(8)
Progenipoietin-1 is an agonist of both the granulocyte colony-stimulating factor and fetal liver tyrosine kinase-3 receptors capable of inducing the proliferation of multiple hematopoietic cell lineages. The potential of progenipoietin-1 to mobilize
Publikováno v:
British journal of haematology. 103(2)
We have previously demonstrated that high levels of allogeneic, donor-derived mouse haemopoietic progenitor cells engraft following in utero transplantation in NOD/SCID mice. To evaluate whether the fetal NOD/SCID haemopoietic microenvironment suppor
Autor:
C, Bomberger, M, Singh-Jairam, G, Rodey, A, Guerriero, A M, Yeager, W H, Fleming, H K, Holland, E K, Waller
Publikováno v:
Blood. 91(7)
T-cell and B-cell reconstitution was studied in nine patients who received fluorescence activated cell sorter (FACS)-sorted autologous CD34+ hematopoietic progenitor cells (HPC). The mean numbers of T cells (CD3+), B cells (CD19+) and CD34+ HPC admin
Publikováno v:
Blood. 90(8)
Substantial barriers exist to the engraftment of hematopoietic cells in mice after in utero transplantation. Although high levels of donor-derived hematopoiesis have been reported in SCID mice, the majority of chimeric recipients exhibit decreasing l
Publikováno v:
Blood. 87(8)
Human hematopoietic progenitor cells (HPCs) from mobilized peripheral blood mononuclear cells (PBMCs), adult bone marrow (ABM), and fetal bone marrow (FBM) were evaluated for their ability to produce multilineage human hematopoietic engraftment in vi
Publikováno v:
Cancer research. 54(18)
Fluctuation analysis experiments were performed in the human sarcoma cell line MES-SA to assess whether selection or induction mechanisms determine resistance to doxorubicin (DOX), mutation rates, and the nature of the surviving clones. Thirteen flas
The in vivo effects of steel factor on natural killer lineage cells in murine spleen and bone marrow
Publikováno v:
Natural immunity. 12(6)
Steel factor (S1F), also known as stem cell factor, is a potent growth stimulator of hemopoietic progenitor cells. In the context of transplantation of hemopoietic cells to irradiated allogeneic hosts, natural killer (NK) cells exert restrictive cont