Zobrazeno 1 - 10
of 33
pro vyhledávání: '"W. Glenn L. Kerrick"'
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0200834 (2018)
Cardiac muscle expresses three neuronal nitric oxide synthase (nNOS) splice variants: nNOSα, nNOSμ and nNOSβ. The functions of these nNOS splice variants in cardiac muscle, particularly myofilament-associated nNOSβ are unclear. To decipher cardia
Externí odkaz:
https://doaj.org/article/f09f83c88f3b4b1fb7d08724eccf0677
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 7, p e0200834 (2018)
PLoS ONE, Vol 13, Iss 7, p e0200834 (2018)
Cardiac muscle expresses three neuronal nitric oxide synthase (nNOS) splice variants: nNOSα, nNOSμ and nNOSβ. The functions of these nNOS splice variants in cardiac muscle, particularly myofilament-associated nNOSβ are unclear. To decipher cardia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41e2f9df31a70f8365f4591754c384b0
https://pubmed.ncbi.nlm.nih.gov/30028847
https://pubmed.ncbi.nlm.nih.gov/30028847
Autor:
Joshua M. Hare, Emmanuel S. Buys, Justin M. Percival, Wayne Balkan, Yuanyuan Xu, Yenong Cao, Younghye Moon, Francisca Diaz, Jingjing Zhu, W. Glenn L. Kerrick
Publikováno v:
Antioxidantsredox signaling. 26(4)
Aim: Nitric oxide (NO) plays important, but incompletely defined roles in skeletal muscle. NO exerts its regulatory effects partly though S-nitrosylation, which is balanced by denitrosylation by enzymes such as S-nitrosoglutathione reductase (GSNOR),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec55d1b9ea0e29198c1a457331e4ec32
https://pubmed.ncbi.nlm.nih.gov/27412893
https://pubmed.ncbi.nlm.nih.gov/27412893
Autor:
Katarzyna Kazmierczak, Yingcai Wang, W. Glenn L. Kerrick, Danuta Szczesna-Cordary, Yuanyuan Xu
Publikováno v:
The FASEB Journal. 23:855-865
Transgenic (Tg) mice expressing ∼95% of the D166V (aspartic acid to valine) mutation in the ventricular myosin regulatory light chain (RLC) shown to cause a malignant familial hypertrophic cardiomyopathy (FHC) phenotype were generated, and the skin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::647f3a906d9e3666d8da22dec04ac9fb
https://doi.org/10.1096/fj.08-118182
https://doi.org/10.1096/fj.08-118182
Autor:
W. Glenn L. Kerrick, James D. Potter, Yuhui Wen, Yuanyuan Xu, Aldrin V. Gomes, Ying Wang, Jose R. Pinto, Yingcai Wang
Publikováno v:
Journal of Biological Chemistry. 283:20484-20494
In this study, we addressed the functional consequences of the human cardiac troponin I (hcTnI) hypertrophic cardiomyopathy R145G mutation in transgenic mice. Simultaneous measurements of ATPase activity and force in skinned papillary fibers from hcT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2af5a2d4830e920b5df2776a6ebe7b3
https://doi.org/10.1074/jbc.m801661200
https://doi.org/10.1074/jbc.m801661200
Autor:
Clara Franzini-Armstrong, W. Glenn L. Kerrick, Paul D. Allen, Jose R. Lopez, Claudio F. Perez, Ying Wang, Anthony H. Caswell, Larry R. Jones, Xiaohua Shen, Yvonne M. Kobayashi, Todd Miller, James D. Potter
Publikováno v:
Journal of Biological Chemistry. 282:37864-37874
To unmask the role of triadin in skeletal muscle we engineered pan-triadin-null mice by removing the first exon of the triadin gene. This resulted in a total lack of triadin expression in both skeletal and cardiac muscle. Triadin knockout was not emb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8053c6839e8f9f8a9f5d7b1e11f8a2a
https://doi.org/10.1074/jbc.m705702200
https://doi.org/10.1074/jbc.m705702200
Autor:
Jiaju Zhao, Todd Miller, Yuanyuan Xu, W. Glenn L. Kerrick, Bjorn C. Knollmann, Danuta Szczesna-Cordary, Ying Wang, Zoraida Diaz, James D. Potter, Olga M. Hernandez, Syevda G. Sirenko, Georgianna Guzman, Michael D. Bell
Publikováno v:
Journal of Biological Chemistry. 280:37183-37194
We have studied the physiological effects of the troponin T (TnT) F110I and R278C mutations associated with familial hypertrophic cardiomyopathy (FHC) in humans. Three to four-month-old transgenic (Tg) mice expressing F110I-TnT and R278C-TnT did not
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0965605a275e48f0499c3673570bc932
https://doi.org/10.1074/jbc.m508114200
https://doi.org/10.1074/jbc.m508114200
Autor:
Yuanyuan Xu, W. Glenn L. Kerrick
Publikováno v:
Journal of Muscle Research and Cell Motility. 25:107-117
The effect of inorganic phosphate (Pi) on Ca2+-activation of actomyosin ATPase activity and force in permeabilized (skinned) single extensor digitorum longus (EDL) and soleus muscle fibers of the rat were investigated. Increasing concentrations of Pi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d147870973fef2dc093f529aba0888
https://doi.org/10.1023/b:jure.0000035841.04314.16
https://doi.org/10.1023/b:jure.0000035841.04314.16
Publikováno v:
Journal of Biological Chemistry. 278:41670-41676
The effects of Troponin T (TnT) mutants R141W and DeltaK210, the only two currently known mutations in TnT that cause dilated cardiomyopathy(DCM) independent of familial hypertrophic cardiomyopathy (FHC), and TnT-K273E, a mutation that leads to a pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::364dc83a2e427eb297f1ba324005a459
https://doi.org/10.1074/jbc.m302148200
https://doi.org/10.1074/jbc.m302148200
Publikováno v:
Journal of Molecular Biology. 322:1065-1088
We have formulated a three-compartment model of muscle activation that includes both strong cross-bridge (XB) and Ca 2+ -activated regulatory-unit (RU) mediated nearest-neighbor cooperative influences. The model is based on the tight coupling premise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::365645383c870d000722fcf25958f5e9
https://doi.org/10.1016/s0022-2836(02)00855-0
https://doi.org/10.1016/s0022-2836(02)00855-0