Zobrazeno 1 - 10
of 55
pro vyhledávání: '"W. Geven"'
Autor:
Irene Di Ceglie, Peter L. E. M. van Lent, Edwin J. W. Geven, Marije I. Koenders, Arjen B. Blom, Thomas Vogl, Johannes Roth, Martijn H. J. van den Bosch
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-12 (2021)
Abstract Background Excessive osteoclast activity, which is strongly stimulated by pro-inflammatory mediators, results in bone and cartilage degeneration as central features of many arthritides. Levels of the alarmin S100A8/A9 and interleukin (IL)-1
Externí odkaz:
https://doaj.org/article/007fde91b5b342df9e647aa4c1e5e630
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0251864 (2021)
Testosterone and alendronate have been identified as two bone healing compounds which, when combined, synergistically stimulate bone regeneration. This study describes the development of a novel ultrasonic spray coating for sustained release of ancil
Externí odkaz:
https://doaj.org/article/a1eec33547784d3b81f047958b97d1af
Autor:
Inja Waldhauer, Valeria Gonzalez-Nicolini, Anne Freimoser-Grundschober, Tapan K Nayak, Linda Fahrni, Ralf J. Hosse, Danny Gerrits, Edwin J. W. Geven, Johannes Sam, Sabine Lang, Esther Bommer, Virginie Steinhart, Elisabeth Husar, Sara Colombetti, Erwin Van Puijenbroek, Markus Neubauer, J. Mark Cline, Pradeep K. Garg, Gregory Dugan, Federica Cavallo, Gonzalo Acuna, Jehad Charo, Volker Teichgräber, Stefan Evers, Otto C. Boerman, Marina Bacac, Ekkehard Moessner, Pablo Umaña, Christian Klein
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
Simlukafusp alfa (FAP-IL2v, RO6874281/RG7461) is an immunocytokine comprising an antibody against fibroblast activation protein α (FAP) and an IL-2 variant with a retained affinity for IL-2Rβγ > IL-2 Rβγ and abolished binding to IL-2 Rα. Here,
Externí odkaz:
https://doaj.org/article/92299c28b9d34a45bf95cf39c2bbc494
Autor:
Bart A. J. A. van Oirschot, John A. Jansen, Cindy J. J. M. van de Ven, Edwin J. W. Geven, Jan A. Gossen
Publikováno v:
eJournal of Oral Maxillofacial Research, Vol 11, Iss 3, p e4 (2020)
Objectives: The purpose of the present in vivo study was to evaluate whether pericard collagen membranes coated with ancillary amounts of testosterone and alendronate in a poly-lactic glycolic acid (PLGA) carrier as compared to uncoated membranes wil
Externí odkaz:
https://doaj.org/article/f2ac343e51724e93bd4f66fc66c835c2
Autor:
Niels A. J. Cremers, Martijn H. J. van den Bosch, Stephanie van Dalen, Irene Di Ceglie, Giuliana Ascone, Fons van de Loo, Marije Koenders, Peter van der Kraan, Annet Sloetjes, Thomas Vogl, Johannes Roth, Edwin J. W. Geven, Arjen B. Blom, Peter L. E. M. van Lent
Publikováno v:
Arthritis Research & Therapy, Vol 19, Iss 1, Pp 1-15 (2017)
Abstract Background Monocytes are dominant cells present within the inflamed synovium during osteoarthritis (OA). In mice, two functionally distinct monocyte subsets are described: pro-inflammatory Ly6Chigh and patrolling Ly6Clow monocytes. Alarmins
Externí odkaz:
https://doaj.org/article/000ad2f4ec3f47dc9d28f7482a1ea756
Autor:
Stephanie C. M. van Dalen, Arjen B. Blom, Birgitte Walgreen, Annet W. Slöetjes, Monique M. A. Helsen, Edwin J. W. Geven, Menno ter Huurne, Thomas Vogl, Johannes Roth, Fons A. J. van de Loo, Marije I. Koenders, Louis Casteilla, Peter M. van der Kraan, Martijn H. J. van den Bosch, Peter L. E. M. van Lent
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Background: Injection of adipose-derived mesenchymal stromal cells (ASCs) into murine knee joints after induction of inflammatory collagenase-induced osteoarthritis (CiOA) reduces development of joint pathology. This protection is only achieved when
Externí odkaz:
https://doaj.org/article/6ad2b9a22dd747d49bfb41f920fc06d9
Autor:
Martijn H J van den Bosch, Thomas Vogl, Johannes Roth, Marije I. Koenders, Irene Di Ceglie, Peter L E M van Lent, Edwin J. W. Geven, Arjen B. Blom
Publikováno v:
Arthritis Research & Therapy, Vol 23, Iss 1, Pp 1-12 (2021)
Arthritis Research & Therapy
Arthritis Research & Therapy, 23
Arthritis Research & Therapy, 23, 1
Arthritis Research & Therapy
Arthritis Research & Therapy, 23
Arthritis Research & Therapy, 23, 1
Background Excessive osteoclast activity, which is strongly stimulated by pro-inflammatory mediators, results in bone and cartilage degeneration as central features of many arthritides. Levels of the alarmin S100A8/A9 and interleukin (IL)-1β are bot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67e48952204a435b24a1f6386fba5caf
https://doaj.org/article/007fde91b5b342df9e647aa4c1e5e630
https://doaj.org/article/007fde91b5b342df9e647aa4c1e5e630
Autor:
Ralf Hosse, Federica Cavallo, Esther Bommer, Danny Gerrits, Valeria Gonzalez-Nicolini, Marina Bacac, Volker Teichgräber, Stefan Evers, Gregory O. Dugan, Tapan K. Nayak, Erwin van Puijenbroek, Inja Waldhauer, Elisabeth Husar, J. Mark Cline, Virginie Steinhart, Gonzalo Acuna, Ekkehard Moessner, Markus Neubauer, Johannes Sam, Edwin J. W. Geven, Pradeep Garg, Sabine Lang, Jehad Charo, Sara Colombetti, Christian Klein, Linda Fahrni, Anne Freimoser-Grundschober, Otto C. Boerman, Pablo Umana
Publikováno v:
mAbs
article-version (VoR) Version of Record
Mabs, 13
Mabs, 13, 1
article-version (VoR) Version of Record
Mabs, 13
Mabs, 13, 1
Simlukafusp alfa (FAP-IL2v, RO6874281/RG7461) is an immunocytokine comprising an antibody against fibroblast activation protein α (FAP) and an IL-2 variant with a retained affinity for IL-2Rβγ > IL-2 Rβγ and abolished binding to IL-2 Rα. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54fe9bb5153efb5907c70c2cecf1c903
https://pubmed.ncbi.nlm.nih.gov/33974508
https://pubmed.ncbi.nlm.nih.gov/33974508
Autor:
Edwin J. W. Geven, Cindy J. J. M. van de Ven, Jan A. Gossen, Nicole E. C. Bakker, Dennis P. Link
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0251864 (2021)
PLoS ONE
PLoS ONE
Testosterone and alendronate have been identified as two bone healing compounds which, when combined, synergistically stimulate bone regeneration. This study describes the development of a novel ultrasonic spray coating for sustained release of ancil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e665284b1226a116fa9fa9aed936a4ff
https://doaj.org/article/a1eec33547784d3b81f047958b97d1af
https://doaj.org/article/a1eec33547784d3b81f047958b97d1af
Autor:
Cindy J. J. M. van de Ven, Bart A. J. A. van Oirschot, Jan A Gossen, John A. Jansen, Edwin J. W. Geven
Publikováno v:
Journal of Oral & Maxillofacial Research
eJournal of Oral & Maxillofacial Research, 11, 3
eJournal of Oral & Maxillofacial Research, 11
eJournal of Oral Maxillofacial Research, Vol 11, Iss 3, p e4 (2020)
eJournal of Oral & Maxillofacial Research, 11, 3
eJournal of Oral & Maxillofacial Research, 11
eJournal of Oral Maxillofacial Research, Vol 11, Iss 3, p e4 (2020)
Contains fulltext : 232819.pdf (Publisher’s version ) (Open Access) OBJECTIVES: The purpose of the present in vivo study was to evaluate whether pericard collagen membranes coated with ancillary amounts of testosterone and alendronate in a poly-lac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10abe6667d41b2fba324897f8931ea5a
https://pubmed.ncbi.nlm.nih.gov/33262883
https://pubmed.ncbi.nlm.nih.gov/33262883