Výsledky vyhledávání - "W. G. Delong"

Molecular requirements for induction of CTGF expression by TGF-β1 in primary osteoblasts

Autor: S.N. Popoff, John A. Arnott, Fayez F. Safadi, X. Zhang, Steven L. Smock, W. G. Delong, Saqib Rehman, Thomas A. Owen, Archana Sanjay

Publikováno v: Bone. 42:871-885

Connective tissue growth factor (CTGF/CCN2) is a cysteine rich, extracellular matrix protein that acts as an anabolic growth factor to regulate osteoblast differentiation and function. In osteoblasts, CTGF is induced by TGF-beta1 where it acts as a d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::471d8a63cb0b49c93e4a8839a0816670
https://doi.org/10.1016/j.bone.2008.01.006

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Evaluation and Treatment of Spinal Injuries in the Patient with Polytrauma

Autor: Rajesh V Patel, W. G. Delong, Edward J. Vresilovic

Publikováno v: Clinical Orthopaedics and Related Research. 422:43-54

Spinal injuries occur frequently in the patient with polytrauma making the knowledge of the evaluation and treatment of these injuries invaluable to the trauma team. In the immediate moments after these injuries, critical steps can be taken to preven

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::112ee648da875a1b779252855c96544f
https://doi.org/10.1097/01.blo.0000130841.41657.d3

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Src is a major signaling component for CTGF induction by TGF-β1 in osteoblasts

Autor: Archana Sanjay, W. G. Delong, Fayez F. Safadi, John A. Arnott, Xue-Qian Zhang, Saqib Rehman, S.N. Popoff

Connective tissue growth factor (CTGF/CCN2) is induced by transforming growth factor beta1 (TGF-beta1) where it acts as a downstream mediator of TGF-beta1 induced matrix production in osteoblasts. We have shown the requirement of Src, Erk, and Smad s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a3278e4f9fe52b3822f155f6133aa8b
https://europepmc.org/articles/PMC2897974/

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Cytokines in patients with polytrauma

Autor: Christopher T. Born, W. G. Delong

Publikováno v: Clinical orthopaedics and related research. (422)

Patients with multiple injuries have alterations in hemodynamic, metabolic, and immune responses that largely are orchestrated by endogenous mediators referred to as cytokines. At the molecular level cytokines act as architects constructing a bluepri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::288a7b7d4c06cb2c6303562aecca5e39
https://pubmed.ncbi.nlm.nih.gov/15187834

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Orthopaedic trauma education: visions for the future through the OTA. Orthopaedic Trauma Association

Autor: C T, Born, W G, DeLong

Publikováno v: Journal of orthopaedic trauma. 13(6)

As the trauma center system continues to expand, not only will the requirement for more and better trained trauma surgeons increase, but the means of educating them will need to become more standardized. The general surgeons recognized this many year

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6987d9d70d2efa8294a613eafeb5c8f5
https://pubmed.ncbi.nlm.nih.gov/10459603

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Graft-versus-host disease in limb transplantation: digital image analysis of bone marrow and TGF-beta expression in situ using a novel 3-D microscope

Autor: R, Ramsamooj, R, Llull, L D, Tatem, K S, Black, V, Lotano, R M, Dalsey, C T, Born, W G, DeLong, C W, Hewitt

Publikováno v: Transplantation proceedings. 28(4)

A subpopulation of parental to hybrid VBMT recipients developed characteristic clinical and histopathologic manifestations of GVHD. These changes are similar to those seen in human GVHD secondary to bone marrow transplantation. Human GVHD also manife

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0ccb9d2fb2405a6f5c697bcd44e11133
https://pubmed.ncbi.nlm.nih.gov/8769145

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