Zobrazeno 1 - 10
of 10
pro vyhledávání: '"W. F. Kline"'
Autor:
Peggy H. Wong, Catherine Z. Matthews, Josee Cote, Marshall Sack, Nancy G. B. Agrawal, Eric Woolf, Arturo G. Porras, Richard Robson, Leslie A. Geer, Suzanne K. Swan, W. F. Kline, Ralph S. Mazenko, Kevin J. Petty, Harry Alcorn, Keith Gottesdiener, Meehung Cho, Thomas Marbury, Jack W. Moncrief, Jules I. Schwartz
Publikováno v:
The Journal of Clinical Pharmacology. 44:48-58
The effect of renal insufficiency on the pharmacokinetics of etoricoxib, a selective inhibitor of cyclooxygenase-2, was examined in 23 patients with varying degrees of renal impairment (12 moderate [creatinine clearance between 30 and 50 mL/min/1.73
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7173647acce972895a25e7da4563bae1
https://doi.org/10.1177/0091270003260338
https://doi.org/10.1177/0091270003260338
Publikováno v:
Journal of Liquid Chromatography & Related Technologies. 22:2125-2137
A sensitive and selective method for the determination of 1-(((7,7-dimethyl-2(S)-(2(S)-amino-4-(methylsulfonyl) butyramido)-bicyclo[2.2.1]-heptan-1(S)-yl) methyl) sulfonyl) - 4 - (2 - methyl-phenyl)-piperazine (L-368,899) in human plasma is described
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::33cb3d2af5b44d5117989d1662430b95
https://doi.org/10.1081/jlc-100101789
https://doi.org/10.1081/jlc-100101789
Autor:
J. Orgee, S. Khan, Samuel D Vasikaran, G. Coombes, Monique N.C. Beneton, W. F. Kline, Arturo G. Porras, David G. Sciberras, Barry J. Gertz, Eugene V. McCloskey, S. Rogers, Sherry D. Holland, Bogdan K. Matuszewski, John A. Kanis
Publikováno v:
Journal of Bone and Mineral Research. 12:1700-1707
Postmenopausal women with established vertebral osteoporosis were studied for 2 years to determine the terminal elimination half-life and the duration of response to treatment with intravenous alendronate (30 mg) given over 4 days. The urinary excret
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ea45f48d2ae3d0e5b09d0e6b59fd468
https://doi.org/10.1359/jbmr.1997.12.10.1700
https://doi.org/10.1359/jbmr.1997.12.10.1700
Autor:
W. F. Kline, Bogdan K. Matuszewski, Sherry D. Holland, Amanda Freeman, Kenneth C. Lasseter, Barry J. Gertz, John C. Mucklow, Arturo G. Porras, Hui Quan
Publikováno v:
Clinical Pharmacology & Therapeutics. 58:288-298
Clinical studies were performed to examine the oral bioavailability of alendronate (4-amino-1-hydroxybutylidene-1,1-bisphosphonate monosodium). All studies, with the exception of one performed in men, involved postmenopausal women. Short-term (24 to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c80b5b9b29813b16b68d82a3a25ca5a0
https://doi.org/10.1016/0009-9236(95)90245-7
https://doi.org/10.1016/0009-9236(95)90245-7
Publikováno v:
Osteoporosis International. 3:13-16
Clinical studies have been performed to investigate the pharmacokinetics and pharmacodynamics of alendronate, an inhibitor of bone resorption for the treatment of osteoporosis. Alendronate is one of the most potent bisphosphonates currently undergoin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f98bbf38f98dda264650c2db59bdc61
https://doi.org/10.1007/bf01623002
https://doi.org/10.1007/bf01623002
Publikováno v:
Biomedical chromatography : BMC. 19(7)
Achiral and chiral liquid chromatographic methods utilizing mass spectrometric detection were developed to investigate the possibility of inversion of configuration at any or all of the chiral centers of the neurokinin-1 (NK-1) receptor antagonist, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aab71f00271c74a3a62732ee6e472eab
https://pubmed.ncbi.nlm.nih.gov/15828059
https://pubmed.ncbi.nlm.nih.gov/15828059
Autor:
Barry J. Gertz, Kanying E. Zhang, W. F. Kline, Kamlesh P. Vyas, Hui Quan, Simon Van Belle, Marina DeSmet, Jacques De Greve, Arturo G. Porras, Veronique Cocquyt, Sherry D. Holland
Publikováno v:
Journal of clinical pharmacology. 39(4)
Alendronate is a potent bisphosphonate that has been studied for the treatment of osteoporosis and Paget's disease of the bone. To examine the pharmacokinetics of this drug, several groups of postmenopausal women were dosed intravenously in several s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::556cd11dfe2dd8d7506ff9e2206d6cd3
https://pubmed.ncbi.nlm.nih.gov/10197297
https://pubmed.ncbi.nlm.nih.gov/10197297
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 276(1)
Alendronate (4-amino-1-hydroxybutylidene bisphosphonate, ALN) is an aminobisphosphonate that is being developed for the treatment of diseases characterized by increased bone resorption. The purpose of this study was to assess the long-term safety of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::358e4dffee51e5853b82fc136fc62039
https://pubmed.ncbi.nlm.nih.gov/8558442
https://pubmed.ncbi.nlm.nih.gov/8558442
Publikováno v:
Journal of pharmaceutical and biomedical analysis. 9(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::defc454ae34966d171283d7737ceb296
https://pubmed.ncbi.nlm.nih.gov/1747406
https://pubmed.ncbi.nlm.nih.gov/1747406
Publikováno v:
Journal of Liquid Chromatography. 8:223-237
A sequential liquid chromatographic (LC) procedure for the determination of polycyclic aromatic hydrocarbons (PAH) in a petroleum crude oil and other complex mixtures is described. The procedure includes normal-phase LC on an aminosilane column to is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2acb9d32f8df8532ae30f96c0dda8625
https://doi.org/10.1080/01483918508067074
https://doi.org/10.1080/01483918508067074