Zobrazeno 1 - 10
of 11
pro vyhledávání: '"W. F. Heath"'
Autor:
K. A. Birch, W. F. Heath, R. N. Hermeling, C. M. Johnston, L. Stramm, C. Dell, C. Smith, J. R. Williamson, A. Reifel-Miller
Publikováno v:
Diabetes. 45:642-650
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03290a2617a99f0855620ab9a909e3be
https://doi.org/10.2337/diabetes.45.5.642
https://doi.org/10.2337/diabetes.45.5.642
Autor:
S G Reams, L J Slieker, Harlan Beall Long, R M Belagaje, W F Heath, Walter N. Shaw, Gerald Stephen Brooke, Ronald E. Chance, C Roundtree, Jules A. Hoffmann
Publikováno v:
Journal of Biological Chemistry. 267:419-425
The hormone insulin is synthesized in the beta cell of the pancreas as the precursor, proinsulin, where the carboxyl terminus of the B-chain is connected to the amino terminus of the A-chain by a connecting or C-peptide. Proinsulin is a weak insulin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c9b98988c87152932241e272ee40aa14
https://doi.org/10.1016/s0021-9258(18)48511-0
https://doi.org/10.1016/s0021-9258(18)48511-0
Publikováno v:
Diabetes. 40:395-400
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29030208ca1a9000a0eaf714c906ab15
https://doi.org/10.2337/diabetes.40.3.395
https://doi.org/10.2337/diabetes.40.3.395
Autor:
M R, Jirousek, J R, Gillig, C M, Gonzalez, W F, Heath, J H, McDonald, D A, Neel, C J, Rito, U, Singh, L E, Stramm, A, Melikian-Badalian, M, Baevsky, L M, Ballas, S E, Hall, L L, Winneroski, M M, Faul
Publikováno v:
Journal of medicinal chemistry. 39(14)
Protein kinase C (PKC) is a family of closely related serine and threonine kinases. Overactivation of some PKC isozymes has been postulated to occur in several diseases states, including diabetic complications. Selective inhibition of overactivated P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cb5ac00681b250b31322178de9017690
https://pubmed.ncbi.nlm.nih.gov/8709095
https://pubmed.ncbi.nlm.nih.gov/8709095
Publikováno v:
Receptor. 3(4)
Arg-Gly-Asp-Ser (RGDS) 1, Arg-Val-Asp-Ser (RVDS) 2, Arg-dVal-Asp-Ser (R[d]VDS) 3, and a cyclic RGD peptide, cyclo S,R [H-Pen-Arg-Gly-Asp-Pen-Gly-OH] 4, were tested for their ability to antagonize GPIIb-IIIa function. The activities were found to fall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::757edf7889f03fcd213cbc2aa61a2328
https://pubmed.ncbi.nlm.nih.gov/8142908
https://pubmed.ncbi.nlm.nih.gov/8142908
Autor:
W F, Heath, R M, Belagaje, G S, Brooke, R E, Chance, J A, Hoffmann, H B, Long, S G, Reams, C, Roundtree, W N, Shaw, L J, Slieker
Publikováno v:
The Journal of biological chemistry. 267(1)
The hormone insulin is synthesized in the beta cell of the pancreas as the precursor, proinsulin, where the carboxyl terminus of the B-chain is connected to the amino terminus of the A-chain by a connecting or C-peptide. Proinsulin is a weak insulin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::415fbbd6cdc569c103134546b0954456
https://pubmed.ncbi.nlm.nih.gov/1730606
https://pubmed.ncbi.nlm.nih.gov/1730606
Publikováno v:
Peptides ISBN: 9789401050050
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5dd29b731ad23bc16e84ec391162580
https://doi.org/10.1007/978-94-011-2264-1_194
https://doi.org/10.1007/978-94-011-2264-1_194
Publikováno v:
Biochemistry. 30(22)
Eleven structural analogues of human basic fibroblast growth factor (bFGF) have been prepared by site-directed mutagenesis of a synthetic bFGF gene to examine the effect of amino acid substitutions in the three putative heparin-binding domains on FGF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed005dff52bd4a3492b5f3ff62ba587f
https://pubmed.ncbi.nlm.nih.gov/2036431
https://pubmed.ncbi.nlm.nih.gov/2036431
Publikováno v:
Chemischer Informationsdienst. 13
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4add90305de6f470703ebd3c8b2ea893
https://doi.org/10.1002/chin.198251346
https://doi.org/10.1002/chin.198251346
Publikováno v:
Chemischer Informationsdienst. 15
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f1dccd85729f05c7eee3c2df32843c2
https://doi.org/10.1002/chin.198404306
https://doi.org/10.1002/chin.198404306