Zobrazeno 1 - 10
of 110
pro vyhledávání: '"W. Donald Shields"'
Autor:
Gregory L. Krauss, Deborah Lee, Yekaterina Dribinsky, W. Donald Shields, Rod Foroozan, Feisal Othman, John M. Pellock, Robert C. Sergott, Edward Faught, Adam Ziemann, Sarah Torri, Jouko Isojarvi
Publikováno v:
Epilepsy & Behavior. 56:15-19
Vigabatrin (Sabril®), approved in the US in 2009, is currently indicated as adjunctive therapy for refractory complex partial seizures (rCPS) in patients ≥ 10 years old who have responded inadequately to several alternative treatments and as monot
Autor:
Eric H. Kossoff, W. Donald Shields
Publikováno v:
Epilepsia. 55:29-33
Summary Individuals with Lennox-Gastaut syndrome (LGS) often do not respond to or become resistant to pharmacologic treatments. Ketogenic diets (KDs) and vagus nerve stimulation (VNS) are nonpharmacologic treatment options for these intractable patie
Autor:
Yekaterina Dribinsky, Adam Ziemann, Rod Foroozan, W. Donald Shields, Deborah Lee, Feisal Othman, Sarah Torri, Edward Faught, John M. Pellock, Robert C. Sergott, Jouko Isojarvi
Publikováno v:
Epilepsybehavior : EB. 60
Vigabatrin (Sabril®) is an antiepileptic drug (AED) currently indicated in the US as a monotherapy for patients 1month to 2years of age with infantile spasms (IS) and as adjunctive therapy for patients ≥10years of age with refractory complex parti
Autor:
John M. Pellock, Edward Faught, Mark A. Weinberg, Gregory A. Burkhart, Rod Foroozan, Gregory L. Krauss, W. Donald Shields, David L. Wesche, Robert C. Sergott
Publikováno v:
Epilepsy & Behavior. 22:710-717
The vigabatrin patient registry was implemented in August 2009 in conjunction with Food and Drug Administration approval of vigabatrin. All US vigabatrin-treated patients must enroll in the registry. Data on prescriber specialty/location, patient dem
Autor:
Jennifer G. Levitt, Prabha Siddarth, Pengju Benjamin Tseng, Matthew Hudkins, Ronald R. Seese, Joseph O'Neill, Suresh Gurbani, Rochelle Caplan, W. Donald Shields, Keng Nei Wu
Publikováno v:
Epilepsia. 52:1705-1714
Summary Purpose: To investigate relationships between regional brain metabolites, social communication deficits, and seizure frequency in children and adolescents with cryptogenic epilepsy with complex partial seizures (CPS). Methods: In 12 children
Autor:
Patricia A. Gibson, James W. Wheless, Douglas R. Nordli, Tallie Z. Baram, John M. Pellock, Dennis J. Dlugos, Gregory L. Holmes, Edwin Trevathan, David Bettis, W. Donald Shields, Christine O'Dell, Shlomo Shinnar, William D. Gaillard, Richard A. Hrachovy
Publikováno v:
Epilepsia. 51:2175-2189
The diagnosis, evaluation, and management of infantile spasms (IS) continue to pose significant challenges to the treating physician. Although an evidence-based practice guideline with full literature review was published in 2004, diversity in IS eva
Autor:
Raman Sankar, W. Donald Shields, Jennifer G. Levitt, Rochelle Caplan, Prabha Siddarth, Suresh Gurbani
Publikováno v:
Epilepsy & Behavior. 18:286-290
This study examined the relationship between suicidal ideation and frontotemporal volumes, particularly orbital frontal gyrus volume, in 51 subjects with epilepsy with a mean age of 9.8 (2.1) years. Structured psychiatric interviews of the children a
Autor:
Stephen M. Sagar, Stephen D. Collins, W. Donald Shields, Roy D. Elterman, Richard M. Bittman, Sarah Torri
Publikováno v:
Journal of Child Neurology. 25:1340-1347
A large randomized study was conducted in patients with newly diagnosed infantile spasms to compare 2 doses of vigabatrin in achieving spasm cessation. High (100-148 mg/kg/d) and low (18-36 mg/kg/d) oral doses of vigabatrin were evaluated in a random
Autor:
W. Donald Shields, O. C. Snead
Publikováno v:
Epilepsia. 50:10-15
Benign epilepsy with centrotemporal spikes (BECTS) is a common disorder in childhood. After a brief overview of BECTS, a review of the data in favor of treatment with anticonvulsant medications is followed by the data indicating that treatment is not
Autor:
M. Frost, Roy D. Elterman, Martina Bebin, Lionel Carmant, Juliann M. Paolicchi, Stephen D. Collins, Catherine Chiron, Mary L. Zupanc, Elizabeth A. Thiele, James W. Wheless, W. Donald Shields, Joan A. Conry
Publikováno v:
Epilepsia. 50:195-205
Summary Purpose: Vigabatrin used to treat infantile spasms (IS) has been associated with transient magnetic resonance imaging (MRI) abnormalities. We carried out a retrospective review to better characterize the frequency of those abnormalities in IS