Zobrazeno 1 - 10
of 545
pro vyhledávání: '"W. Dodson"'
Autor:
Mark G. Young, Timothy J. Straub, Colin J. Worby, Hayden C. Metsky, Andreas Gnirke, Ryan A. Bronson, Lucas R. van Dijk, Christopher A. Desjardins, Christian Matranga, James Qu, Jesús Bazan Villicana, Philippe Azimzadeh, Andrew Kau, Karen W. Dodson, Henry L. Schreiber, Abigail L. Manson, Scott J. Hultgren, Ashlee M. Earl
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Low-abundance members of microbial communities are difficult to study in their native habitats, including Escherichia coli, a minor but common inhabitant of the gastrointestinal tract, and key opportunistic pathogen of the urinary tract. Whi
Externí odkaz:
https://doaj.org/article/8e844166628947188462fb7815e99761
Autor:
Taylor M. Nye, Zongsen Zou, Chloe L. P. Obernuefemann, Jerome S. Pinkner, Erin Lowry, Kent Kleinschmidt, Karla Bergeron, Aleksandra Klim, Karen W. Dodson, Ana L. Flores-Mireles, Jennifer N. Walker, Daniel Garrett Wong, Alana Desai, Michael G. Caparon, Scott J. Hultgren
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Catheter-associated urinary tract infections (CAUTIs), a common cause of healthcare-associated infections, are caused by a diverse array of pathogens that are increasingly becoming antibiotic resistant. We analyze the microbial occurrences i
Externí odkaz:
https://doaj.org/article/bbcf2d87b3694f7e89d8818948dfec1e
Autor:
Brittany M. Scarpato, Brian W. Locke, Joseph Bledsoe, Daniel B. Knox, Karen Conner, Gregory J. Stoddard, Meghan M. Cirulis, Charles Gregory Elliott, Mark W. Dodson
Publikováno v:
Pulmonary Circulation, Vol 13, Iss 2, Pp n/a-n/a (2023)
Abstract Findings of an enlarged pulmonary artery diameter (PAd) and increased pulmonary artery to ascending aorta ratio (PA:AA) on contrast‐enhanced computed tomography pulmonary angiography (CTPA) are associated with increased mortality in partic
Externí odkaz:
https://doaj.org/article/3d2fe4b5bf3e4b9c80f36adc1f214ffd
Publikováno v:
Pulmonary Circulation, Vol 12, Iss 4, Pp n/a-n/a (2022)
Abstract Chronic thromboembolic pulmonary hypertension (CTEPH) and acute pulmonary embolism (PE) are related phenotypes, however, previous reports have suggested that genetic risk factors for CTEPH and PE differ. Here we report that a family history
Externí odkaz:
https://doaj.org/article/41c77f95a2e7453888e62838094eaf65
Autor:
Timothy J. Straub, Wen-Chi Chou, Abigail L. Manson, Henry L. Schreiber, Bruce J. Walker, Christopher A. Desjardins, Sinéad B. Chapman, Kerrie L. Kaspar, Orsalem J. Kahsai, Elizabeth Traylor, Karen W. Dodson, Meredith A. J. Hullar, Scott J. Hultgren, Christina Khoo, Ashlee M. Earl
Publikováno v:
BMC Microbiology, Vol 21, Iss 1, Pp 1-17 (2021)
Abstract Background Urinary tract infections (UTIs) affect 15 million women each year in the United States, with > 20% experiencing frequent recurrent UTIs. A recent placebo-controlled clinical trial found a 39% reduction in UTI symptoms among recurr
Externí odkaz:
https://doaj.org/article/5c7c3468a1dc4d208ef6d1c73577946d
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 5 (2022)
Externí odkaz:
https://doaj.org/article/3a5f29334ea64e1f9ee71e0a3f5098e7
Autor:
Mark W. Dodson MD, PhD, Meghan M. Cirulis MM, MD, Haojia Li MS, Zhang Yue PhD, Lynette M. Brown MD, PhD, C. Gregory Elliott MD
Publikováno v:
Clinical and Applied Thrombosis/Hemostasis, Vol 28 (2022)
Chronic thromboembolic pulmonary hypertension (CTEPH) is a serious complication of acute pulmonary embolism (PE) which remains underdiagnosed. A better understanding of risk factors for CTEPH would improve our ability to predict which PE survivors ar
Externí odkaz:
https://doaj.org/article/74cdff9475ea41f290965745379fc4b6
Publikováno v:
mBio, Vol 11, Iss 5 (2020)
ABSTRACT Urinary tract infections (UTIs) are predominantly caused by uropathogenic Escherichia coli (UPEC). UPEC pathogenesis requires passage through a severe population bottleneck involving intracellular bacterial communities (IBCs) that are clonal
Externí odkaz:
https://doaj.org/article/23fc2786fb1345899573ba2c852d6774
Autor:
Alexandra E. Paharik, Henry L. Schreiber, Caitlin N. Spaulding, Karen W. Dodson, Scott J. Hultgren
Publikováno v:
Genome Medicine, Vol 9, Iss 1, Pp 1-4 (2017)
Editorial summary Antibiotics have become the standard of care for bacterial infections. However, rising rates of antibiotic-resistant infections are outpacing the development of new antimicrobials. Broad-spectrum antibiotics also harm beneficial mic
Externí odkaz:
https://doaj.org/article/f84b021d73e44538a9cc72a810556195
Autor:
Carl A. Machutta, Christopher S. Kollmann, Kenneth E. Lind, Xiaopeng Bai, Pan F. Chan, Jianzhong Huang, Lluis Ballell, Svetlana Belyanskaya, Gurdyal S. Besra, David Barros-Aguirre, Robert H. Bates, Paolo A. Centrella, Sandy S. Chang, Jing Chai, Anthony E. Choudhry, Aaron Coffin, Christopher P. Davie, Hongfeng Deng, Jianghe Deng, Yun Ding, Jason W. Dodson, David T. Fosbenner, Enoch N. Gao, Taylor L. Graham, Todd L. Graybill, Karen Ingraham, Walter P. Johnson, Bryan W. King, Christopher R. Kwiatkowski, Joël Lelièvre, Yue Li, Xiaorong Liu, Quinn Lu, Ruth Lehr, Alfonso Mendoza-Losana, John Martin, Lynn McCloskey, Patti McCormick, Heather P. O’Keefe, Thomas O’Keeffe, Christina Pao, Christopher B. Phelps, Hongwei Qi, Keith Rafferty, Genaro S. Scavello, Matt S. Steiginga, Flora S. Sundersingh, Sharon M. Sweitzer, Lawrence M. Szewczuk, Amy Taylor, May Fern Toh, Juan Wang, Minghui Wang, Devan J. Wilkins, Bing Xia, Gang Yao, Jean Zhang, Jingye Zhou, Christine P. Donahue, Jeffrey A. Messer, David Holmes, Christopher C. Arico-Muendel, Andrew J. Pope, Jeffrey W. Gross, Ghotas Evindar
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Encoded Library Technology (ELT) has streamlined the identification of chemical ligands for protein targets in drug discovery. Here, the authors optimize the ELT approach to screen multiple proteins in parallel and identify promising targets and anti
Externí odkaz:
https://doaj.org/article/a0c4424f2eeb46a689586e4828ae7887