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Dose rationale and pharmacokinetics of dexmedetomidine in mechanically ventilated new-borns: impact of design optimisation

Autor: Oscar Della Pasqua, Johan Vande Walle, Pieter De Cock, Karel Allegaert, W Decaluwe, Anne Smits, Sven C. van Dijkman, Peter De Paepe, Koenraad Smets

Publikováno v: EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY
European Journal of Clinical Pharmacology, 75(10), 1393-1404. Springer-Verlag

PURPOSE: There is a need for alternative analgosedatives such as dexmedetomidine in neonates. Given the ethical and practical difficulties, protocol design for clinical trials in neonates should be carefully considered before implementation. Our obje

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6672ed6c17d0e6974e51c6b4eff85a7d
https://pubmed.ncbi.nlm.nih.gov/31312867

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Outbreak of leptospirosis during a scout camp in the Luxembourg Belgian province, Belgium, summer 2012

Autor: Marcella Mori, Marijke Reynders, S. Depoorter, M Van Esbroeck, S. J. Vandecasteele, W. Decaluwe, David Fretin

Publikováno v: Epidemiol Infect

SUMMARYAn outbreak of leptospirosis occurred in the South of Belgium, during August 2012, in teenagers who participated in two consecutive adventure scout camps near the Semois river. Among the symptomatic patient population (ten scouts), clinical ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::921889c60afd21c4901046d73795ff0d
https://doi.org/10.1017/s0950268814002763

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Akademický článek

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Mosaic tetrasomy 15q25→qter in a newborn infant with multiple anomalies

Autor: W. Decaluwe, Franki Speleman, N. Van Roy, M. R. Verschraegen-Spae, A. Van den Enden, C. De Praeter

Publikováno v: American Journal of Medical Genetics. 63:482-485

We describe a premature boy with metopic craniosynostosis, facial anomalies, atrial-septal defect, hydronephrosis and flexion contractures of lower limbs, and mosaic tetrasomy 15q25{r_arrow}qter. The extra chromosome material was present in the form

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::70e798ed5165f8f273c1b80d0dcc89e8
https://doi.org/10.1002/(sici)1096-8628(19960614)63:3<482::aid-ajmg13>3.0.co

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Prophylactic ibuprofen in premature infants: a multicentre, randomised, double-blind, placebo-controlled trial

Autor: Alexandra Casaer, Bart Van Overmeire, Ann Jespers, Inge Harrewijn, Joost Weyler, Christian Debauche, W Decaluwe, Jean-Paul Langhendries, Karel Allegaert

Publikováno v: The lancet : international edition

Background Ibuprofen is used for treatment and prevention of patent ductus arteriosus in low-birthweight infants. Its effects on regional circulations differ from those of indometacin. Because prophylactic indometacin reduces the frequency of severe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4228e51a9dfe0babfa2d19f825e70702
https://hdl.handle.net/10067/495070151162165141

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Mosaic tetrasomy 15q25--qter in a newborn infant with multiple anomalies

Autor: A, Van den Enden, M R, Verschraegen-Spae, N, Van Roy, W, Decaluwe, C, De Praeter, F, Speleman

Publikováno v: American journal of medical genetics. 63(3)

We describe a premature boy with metopic craniosynostosis, facial anomalies, atrial-septal defect, hydronephrosis and flexion contractures of lower limbs, and mosaic tetrasomy 15q25--qter. The extra chromosome material was present in the form of an a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::0744aeb6c9b0794a4e1db71166ae8f6a
https://pubmed.ncbi.nlm.nih.gov/8737657

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