Zobrazeno 1 - 10
of 402
pro vyhledávání: '"W. David Wilson"'
Autor:
J. Ross Terrell, Thao T. Le, Ananya Paul, Margo A. Brinton, W. David Wilson, Gregory M. K. Poon, Markus W. Germann, Jessica L. Siemer
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-10 (2024)
Abstract Potential G-quadruplex sites have been identified in the genomes of DNA and RNA viruses and proposed as regulatory elements. The genus Orthoflavivirus contains arthropod-transmitted, positive-sense, single-stranded RNA viruses that cause sig
Externí odkaz:
https://doaj.org/article/8e9f01cae3524f5faf463f7f903561c0
Autor:
J. Ross Terrell, Samuel J. Taylor, Amelia L. Schneider, Yue Lu, Tyler N. Vernon, Suela Xhani, Ryan H. Gumpper, Ming Luo, W. David Wilson, Ulrich Steidl, Gregory M.K. Poon
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112671- (2023)
Summary: The master transcriptional regulator PU.1/Spi-1 engages DNA sites with affinities spanning multiple orders of magnitude. To elucidate this remarkable plasticity, we have characterized 22 high-resolution co-crystallographic PU.1/DNA complexes
Externí odkaz:
https://doaj.org/article/3a08b530979c4b649e48bbf830396248
Autor:
Mathijs J. P. Theelen, W. David Wilson, Barbara A. Byrne, Judy M. Edman, Philip H. Kass, Lapo Mughini‐Gras, K. Gary Magdesian
Publikováno v:
Journal of Veterinary Internal Medicine, Vol 34, Iss 2, Pp 955-963 (2020)
Abstract Background Antimicrobial treatment protocols for foals with sepsis that do not improve clinically often are adjusted based on bacteriological and antimicrobial susceptibility testing results from samples collected at hospital admission. Obje
Externí odkaz:
https://doaj.org/article/dec70cb4406f4cb3b8f5598ccb873531
Publikováno v:
Life, Vol 12, Iss 5, p 681 (2022)
Ken Breslauer began studies on the thermodynamics of small cationic molecules binding in the DNA minor groove over 30 years ago, and the studies reported here are an extension of those ground-breaking reports. The goals of this report are to develop
Externí odkaz:
https://doaj.org/article/195dc44dee6040369a654f4f3bdfe658
Autor:
Sarah Laughlin, W. David Wilson
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 10, Pp 24506-24531 (2015)
Electrospray ionization mass spectrometry has become invaluable in the characterization of macromolecular biological systems such as nucleic acids and proteins. Recent advances in the field of mass spectrometry and the soft conditions characteristic
Externí odkaz:
https://doaj.org/article/95120788e788415fb0f2e5a034e8fbb3
Publikováno v:
Molecules, Vol 24, Iss 5, p 946 (2019)
We review the preparation of new compounds with good solution and cell uptake properties that can selectively recognize mixed A·T and G·C bp sequences of DNA. Our underlying aim is to show that these new compounds provide important new biotechnolog
Externí odkaz:
https://doaj.org/article/9586be5de2e64df4924462551d1357ea
Autor:
Markus W. Germann, W. David Wilson, Maged M. Henary, Hang T. Huynh, Ekaterina M. Stroeva, Tyler L. Dost, Rupesh Nanjunda, Leah Mickelson, Eric A. Owens
Publikováno v:
Molecules, Vol 18, Iss 11, Pp 13588-13607 (2013)
A variety of cyanines provide versatile and sensitive agents acting as DNA stains and sensors and have been structurally modified to bind in the DNA minor groove in a sequence dependent manner. Similarly, we are developing a new set of cyanines that
Externí odkaz:
https://doaj.org/article/69307b3ba0fb4a56abb5b03f74b13316
Autor:
Edwin N. Ogbonna, Ananya Paul, Abdelbasset A. Farahat, J. Ross Terrell, Ekaterina Mineva, Victor Ogbonna, David W Boykin, W. David Wilson
Publikováno v:
ACS Bio & Med Chem Au.
Publikováno v:
Current Protocols. 3
Autor:
Abdelbasset A. Farahat, Arvind Kumar, Tanja Wenzler, Reto Brun, Ananya Paul, Pu Guo, W. David Wilson, David W. Boykin
New analogs of the antiprotozoal agent Furamidine were prepared utilizing Stille coupling reactions and amidation of the bisnitrile intermediate using lithium bis-trimethylsilylamide. Both the phenyl groups and the furan moiety of furamidine were rep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e49411482d3e0a0f86edc530532fd2a