Zobrazeno 1 - 10
of 131
pro vyhledávání: '"W. David Lust"'
Autor:
Mark A. Smith, W. David Lust, Michele C. Walsh, Juan Sastre, Steven L. Gelfand, George Perry, Máximo Vento, Richard J. Martin
Publikováno v:
Neonatology. 94:293-299
Background: With current evidence, no specific oxygen concentration can yet be recommended in the resuscitation of the depressed term neonate. Objectives: To design a neonatal rat model of resuscitation that mimics birth hypoxia and allows the study
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe978958c9e15f9b2e0eacb1d9000526
https://doi.org/10.1159/000151649
https://doi.org/10.1159/000151649
Autor:
Marek Buczek, Shenandoah Robinson, Jennifer L. Zechel, Warren R. Selman, W. David Lust, Svetlana Pundik
Publikováno v:
Metabolic Brain Disease. 21:309-317
Increasing evidence indicates that fetal metabolic stress may result in a variety of post-natal perturbations during brain development. The goal of the study was to determine the duration of hypoxia/ischemia that would elicit a demonstrable regional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44c4b3da8dce8c23ed6fad584de365ab
https://doi.org/10.1007/s11011-006-9031-4
https://doi.org/10.1007/s11011-006-9031-4
Publikováno v:
Brain Research. 1071:208-217
Resuscitation from cardiac arrest results in reperfusion injury that leads to increased postresuscitation mortality and delayed neuronal death. One of the many consequences of resuscitation from cardiac arrest is a derangement of energy metabolism an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1d1c057af4c09e9234b3b6986a802b4
https://doi.org/10.1016/j.brainres.2005.11.060
https://doi.org/10.1016/j.brainres.2005.11.060
Autor:
Allyn Peterson, Warren R. Selman, Michelle Puchowicz, Jennifer L. Zechel, Jorge L. Gamboa, W. David Lust
Publikováno v:
Birth Defects Research Part B: Developmental and Reproductive Toxicology. 74:287-299
BACKGROUND: Neonatal neurodevelopment is influenced by a variety of external factors, although the mechanisms responsible are poorly understood. Prenatal hypoxia, from physiological or chemical sources, can have no discernible effect, or can result i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82d16a397cd534de10743336715db587
https://doi.org/10.1002/bdrb.20051
https://doi.org/10.1002/bdrb.20051
Autor:
W. David Lust, Danielle L. Magness, C. Miller, Timothy S. Kern, Michelle Puchowicz, Joseph C. LaManna, Kui Xu
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 24:449-457
Diabetes is associated with extensive microvascular pathology and decreased expression of the glucose transporter (GLUT-1) in retina, but not brain. To explore the basis of these differences, the authors simultaneously measured glucose influx (μmol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b17e92cb1f2932a99d6021df0bbe0a50
https://doi.org/10.1097/00004647-200404000-00010
https://doi.org/10.1097/00004647-200404000-00010
Publikováno v:
Brain Research. 999:167-174
Spreading depression (SD) has been demonstrated following focal ischemia, and the additional workload imposed by SD on a tissue already compromised by a marked reduction in blood flow may contribute to the evolution of irreversible damage in the isch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6564a05c7707871d9e401c2989f2498c
https://doi.org/10.1016/j.brainres.2003.11.016
https://doi.org/10.1016/j.brainres.2003.11.016
Autor:
Jennifer L. Zechel, Jorge L. Gamboa, Robert A. Ratcheson, W. David Lust, Warren R. Selman, Graham Mouw
Publikováno v:
NeuroReport. 14:183-186
The endoplasmic reticulum (ER) is emerging as a contributory component of cell death after ischemia. Since caspase-12 has been localized to the ER and is a novel signal for apoptosis, we examined the message levels and protein expression of caspase-1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::553881a2cf48ba3fe056da78a9deafec
https://doi.org/10.1097/00001756-200302100-00004
https://doi.org/10.1097/00001756-200302100-00004
Autor:
Warren R. Selman, Marek Buczek, Jennifer L. Zechel, Yinong Zhou, Svetlana Pundik, W. David Lust
Publikováno v:
Metabolic Brain Disease. 18:195-206
The regional energy status and the availability of metabolic substrates during brain development are important, since a variety of fetal metabolic insults have been increasingly implicated in the evolution of neonatal brain disorders. The response of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e4f40f63069de58ddecf59f71f9b97d2
https://doi.org/10.1023/a:1025503115837
https://doi.org/10.1023/a:1025503115837
Publikováno v:
Metabolic Brain Disease. 17:113-121
Reperfusion injury is believed to contribute to the pathophysiology of ischemic cell death, but the precipitating factors have yet to be completely elucidated. The goal of this study was to examine if reflow-induced secondary energy failure is a comp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca6b1d9818a5dd43cf8c69bf8ffe999d
https://doi.org/10.1023/a:1015420222334
https://doi.org/10.1023/a:1015420222334
Autor:
Graham Mouw, Warren R. Selman, Yifang Zhou, Robert A. Ratcheson, W. David Lust, Jennifer L. Zechel
Publikováno v:
Metabolic Brain Disease. 17:143-151
Cerebral ischemia initiates a program of cell death known as apoptosis. Early steps in these death promoting events are the release of cytochrome c from the mitochondria and activation of caspase-9. The purpose of this report is to determine if the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72662aba4d7ac76887ed6b64ac51960d
https://doi.org/10.1023/a:1019921904378
https://doi.org/10.1023/a:1019921904378