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pro vyhledávání: '"W. Darrell Capel"'
Autor:
Jennifer F. Barnhill, Julie A. Pitcher, David T. Lodowski, W. Darrell Capel, Robert J. Lefkowitz, John J.G. Tesmer
Publikováno v:
Acta Crystallographica Section D Biological Crystallography. 59:936-939
G protein-coupled receptor kinase 2 (GRK2) phosphorylates activated G protein-coupled receptors (GPCRs), which ultimately leads to their desensitization and/or downregulation. The enzyme is recruited to the plasma membrane via the interaction of its
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecb26afa5a3496700c7b4f7ead714960
https://doi.org/10.1107/s0907444903002622
https://doi.org/10.1107/s0907444903002622
Publikováno v:
Science (New York, N.Y.). 300(5623)
The phosphorylation of heptahelical receptors by heterotrimeric guanine nucleotide–binding protein (G protein)–coupled receptor kinases (GRKs) is a universal regulatory mechanism that leads to desensitization of G protein signaling and to the act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a1854190cd0eebee31d3b63b9fb1a7b
https://pubmed.ncbi.nlm.nih.gov/12764189
https://pubmed.ncbi.nlm.nih.gov/12764189
Autor:
Stuart Handwerger, W. Darrell Capel
Publikováno v:
The Journal of clinical endocrinology and metabolism. 61(5)
Anterior pituitary cells and other endocrine cells which synthesize and release protein hormones share the cell surface ganglioside antigens A2B5 and 3G5. In addition, these peptide hormone-producing cells contain chromogranin, a major protein compon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81616e7c231459cfe9b4f49d8e23be2c
https://pubmed.ncbi.nlm.nih.gov/3900121
https://pubmed.ncbi.nlm.nih.gov/3900121
Akademický článek
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