Zobrazeno 1 - 10
of 61
pro vyhledávání: '"W. D. Lust"'
Autor:
Jorge L. Gamboa, Jaroslaw Aronowski, Gary E. Landreth, N. A. Victor, X. Zhao, W. D. Lust, E. W. Wanderi, K. Deininger, Sophy Sundararajan
Publikováno v:
European Journal of Neuroscience. 24:1653-1663
Stroke is a devastating disease with limited treatment options. Recently, we found that the peroxisome proliferator-activated receptor-gamma (PPARgamma) agonists troglitazone and pioglitazone reduce injury and inflammation in a rat model of transient
Autor:
Musa A. Haxhiu, Kimberly L. Kutina-Nelson, Bernadette O. Erokwu, Neil S. Cherniack, Edwin R. Yeh, Joseph C. LaManna, W. D. Lust, Svetlana Pundik
Publikováno v:
Journal of Applied Physiology. 81:1772-1777
LaManna, J. C., M. A. Haxhiu, K. L. Kutina-Nelson, S. Pundik, B. Erokwu, E. R. Yeh, W. D. Lust, and N. S. Cherniack.Decreased energy metabolism in brain stem during central respiratory depression in response to hypoxia. J. Appl. Physiol. 81(4): 1772
Publikováno v:
Epilepsia. 37:258-261
Ketosis is beneficial for seizure control, possibly through induction of cerebral acidosis. However, cerebral intracellular pH has not previously been measured in ketotic humans and the animal data are sparse. We describe a high-fat diet, avidly cons
Publikováno v:
Journal of Neurosurgery. 80:1085-1090
✓ Temporary occlusion of an intracranial artery is frequently necessary in the surgical management of intracranial aneurysms, arteriovenous malformations, and tumors. While the risks of vessel damage associated with clip application have been lesse
Autor:
W. D. Lust, E. A. Palatinsky, Rajesh N. Kalaria, Hardy W. Chan, George Perry, Earl R. Shelton, D. H. Pennington, S. U. Bhatti
Publikováno v:
NeuroReport. 4:211-214
We used various antibodies to the beta amyloid precursor protein (APP) of Alzheimer's disease to study changes in the cellular distribution of APP in experimental ischemic brain injury. In contrast to sham operated controls, rats with repeated revers
Publikováno v:
Magnetic Resonance in Medicine. 22:167-174
The gerbil model of unilateral cerebral ischemia has been used to test the temporal and spatial stability of the MRI T2 effects of oxygen-17 water. Following unilateral carotid ligation, symptomatic animals were given a single large intraperitoneal i
Autor:
R. C. Crumrine, W. D. Lust, Jenkins C, Joseph C. LaManna, Rosenstein Cc, Warren R. Selman, Robert A. Ratcheson
Publikováno v:
Metabolic Brain Disease. 6:57-64
The metabolic characteristics of the penumbral region were examined in spontaneously hypertensive rats one hour after permanent middle cerebral artery occlusion. The effect of hyperglycemia on this region was examined by providing a glucose load prio
Autor:
Anthony J. Ricci, H. M. Assaf, W. D. Lust, Tim S. Whittingham, Joseph C. LaManna, Robert A. Ratcheson
Publikováno v:
Metabolic Brain Disease. 5:143-154
Lactic acid accumulation has been implicated in the evolution of brain damage after ischemia. Since compartmentation of lactate may play a role in acid-base balance, lactate release from gerbil hippocampal slices was examined during a number of metab
Impairment of metabolic recovery with increasing periods of middle cerebral artery occlusion in rats
Autor:
W. D. Lust, Warren R. Selman, Robert A. Ratcheson, Joseph C. LaManna, Anthony J. Ricci, R. C. Crumrine
Publikováno v:
Stroke. 21:467-471
We examined the consequences of reflow on metabolic recovery following increasing periods of focal ischemia. The middle cerebral artery of 21 Sprague-Dawley rats was occluded with a snare ligature for 1, 2, or 6 hours followed by 5, 4, or 0 hours of
Autor:
W. D. Lust, E. W. Wanderi, Jorge L. Gamboa, Gary E. Landreth, Sophy Sundararajan, N. A. Victor
Publikováno v:
Neuroscience. 130(3)
Newly developed insulin-sensitizing agents, which target the nuclear receptor peroxisome proliferator-activated receptor-gamma have recently been appreciated to exhibit potent anti-inflammatory actions. Since stroke is associated with an intense infl