Výsledky vyhledávání - "W. D. Fraser"

High Bone Mass is associated with bone-forming features of osteoarthritis in non-weight bearing joints independent of body mass index

Autor: C L, Gregson, S A, Hardcastle, A, Murphy, B, Faber, W D, Fraser, M, Williams, G, Davey Smith, J H, Tobias

Publikováno v: Bone

Objectives High Bone Mass (HBM) is associated with (a) radiographic knee osteoarthritis (OA), partly mediated by increased BMI, and (b) pelvic enthesophytes and hip osteophytes, suggestive of a bone-forming phenotype. We aimed to establish whether HB

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ec28e7b7d7f0fe60d4390d10d7f91113
https://pubmed.ncbi.nlm.nih.gov/28082078

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Human keratinocytes express transcripts for three isoforms of parathyroid hormone-related protein (PTHrP), but not for the parathyroid hormone/PTHrP receptor: effects of 1,25(OH)2 vitamin D3

Autor: G R, Sharpe, J P, Dillon, B, Durham, J A, Gallagher, W D, Fraser

Publikováno v: British Journal of Dermatology. 138:944-951

Parathyroid hormone-related protein (PTHrP) is strongly expressed in the epidermis and has been implicated in the regulation of growth and differentiation of keratinocytes. PTHrP has N-terminal sequence homology with parathyroid hormone (PTH) and bin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e69d0a33ec544730a8ab4b630e1fc56
https://doi.org/10.1046/j.1365-2133.1998.02259.x

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Performance during Positive Pressure Breathing after Rapid Decompression Up to 72000 Feet

Autor: W. D. Fraser, Barry Fowler, Ann Elise Lindeis

Publikováno v: Human Factors: The Journal of the Human Factors and Ergonomics Society. 39:102-110

Positive pressure breathing (PPB) is a survival system that delivers high-pressure oxygen and body counterpressure in the event of cockpit depressurization at high altitude, but the ability of aircrew to perform an emergency "get-me-down" maneuver wi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e5599f2da89eff983f7dfd488b0a3a0
https://doi.org/10.1518/001872097778940641

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Effects of Atenolol, Labetalol and Methyldopa on Endogenous Antioxidants In-vitro

Autor: William Ewen Smith, G. Chen, James H. McKillop, Grant Cumming, Jamie J. Walker, Rhoda Wilson, W. D. Fraser

Publikováno v: Journal of Pharmacy and Pharmacology. 47:42-45

The aim of this study was to investigate whether atenolol, labetalol and methyldopa, which are commonly used for the treatment of hypertension in pregnancy, can induce antioxidant activity. Reactive oxygen species scavengers (plasma thiol, red cell l

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3feae170df82a0b4f3c903929816d911
https://doi.org/10.1111/j.2042-7158.1995.tb05731.x

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Longitudinal vitamin D status in pregnancy and the risk of pre-eclampsia

Autor: S Q, Wei, F, Audibert, N, Hidiroglou, K, Sarafin, P, Julien, Y, Wu, Z C, Luo, W D, Fraser

Publikováno v: BJOG : an international journal of obstetrics and gynaecology. 119(7)

Whether vitamin D deficiency in pregnancy is a cause of pre-eclampsia remains controversial. Most previous studies to date have assessed exposure at only one time-point in pregnancy. We assessed longitudinal vitamin D status during pregnancy and the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bae09ee2616315779636ddd4c7114154
https://pubmed.ncbi.nlm.nih.gov/22979971

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Long-term follow-up for mortality and cancer in a randomized placebo-controlled trial of vitamin D(3) and/or calcium (RECORD trial)

Autor: Alison, Avenell, Graeme S, MacLennan, David J, Jenkinson, Gladys C, McPherson, Alison M, McDonald, Puspa R, Pant, Adrian M, Grant, Marion K, Campbell, Frazer H, Anderson, Cyrus, Cooper, Roger M, Francis, William J, Gillespie, C Michael, Robinson, David J, Torgerson, W Angus, Wallace, W D, Fraser

Publikováno v: The Journal of clinical endocrinology and metabolism. 97(2)

CONTEXT: Vitamin D or calcium supplementation may have effects on vascular disease and cancer. OBJECTIVE: Our objective was to investigate whether vitamin D or calcium supplementation affects mortality, vascular disease, and cancer in older people. D

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::788fa78dc60495e7650573267a647ff1
http://ora.ox.ac.uk/objects/uuid:2d903a67-b634-4c9c-93f0-4218a1e68c91

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Parental origin of Gs alpha gene mutations in Albright's hereditary osteodystrophy

Autor: Richard C. Trembath, M. E. M. Oude Luttikhuis, W D Fraser, Peter E. Clayton, Louise C. Wilson

Publikováno v: Journal of Medical Genetics. 31:835-839

Heterozygous mutations of the Gs alpha gene leading to reduced Gs alpha activity have been identified in patients with Albright's hereditary osteodystrophy (AHO). However, AHO may be associated with hormone resistance (pseudohypoparathyroidism type I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90da5df1657f8652b4566dc00598b96f
https://doi.org/10.1136/jmg.31.11.835

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