Zobrazeno 1 - 10
of 254
pro vyhledávání: '"W. Cullmann"'
Publikováno v:
International Journal of Antimicrobial Agents. 6:S1-S7
The two β-lactamase inhibitors, sulbactam and clavulanic acid, exhibit high affinity ( K I −6 mol/l) for the β-lactamases of Gram-negative organisms with predominantly penicillinase activity and much less affinity (especially clavulanic acid) for
Autor:
W. Cullmann
Publikováno v:
Chemotherapy. 42:11-20
In this multicenter study conducted in eight European countries, 13,173 pathogens--all isolated from community-acquired infections in 1992 and 1993--were evaluated for their susceptibility to the following orally active antibiotics: penicillin G, amp
Autor:
Johannes Kneer, Wolfgang König, Margot Kissling, U. Chadbourne, George L. Petrikkos, Ron Dagan, J. Scheffer, G. Höffken, W. Cullmann
Publikováno v:
Respiration. 60:I-V
Publikováno v:
International Journal of Antimicrobial Agents. 2:203-230
Within the past decade several new fluoroquinolones (norfloxacin, enoxacin, ofloxacin, ciprofloxacin, pefloxacin, temafloxacin and lomefloxacin) have been introduced into therapy. All these agents share a broad spectrum of activity against a variety
Publikováno v:
Médecine et Maladies Infectieuses. 22:548-555
Summary The cephalosporins cefetamet and cefaclor were studied with regard to their effects to modulate the chemiluminescence response, phagocytosis, bactericidal action and leukotriene formation from human granulocytes and the release of histamine f
Autor:
W. Cullmann
Publikováno v:
Médecine et Maladies Infectieuses. 22:529-534
Summary The enzymes called BRO-1 (formerly called “Ravasio-type”) and BRO-2 (formerly called “1908-type”) are the most predominantly observed β-lactamases in clinical Moraxella catarrhalis isolates. Both of these enzymes can be observed on a
Autor:
Klaus Stoeckel, Margot Kissling, Johannes Kneer, David J. Edwards, Heinrich Urwyler, W. Cullmann
Publikováno v:
International Journal of Antimicrobial Agents. 1:175-191
Cefetamet pivoxil is an oral, third-generation cephalosporin whose broad spectrum of antibacterial activity and favorable pharmacokinetic profile make it particularly suitable for the treatment of a wide range of infectious diseases. Cefetamet has hi
Autor:
H. Schlunegger, W. Cullmann
Publikováno v:
Chemotherapy. 38:211-217
The influence of various nutrient media, growth temperature, phase of growth and subinhibitory concentrations of antibiotics from various groups on the cytoplasmic membrane proteins was studied in 6 c
Autor:
W. Cullmann
Publikováno v:
Chemotherapy. 38:10-17
Phenotypic resistance to beta-lactam antibiotics is mainly due to the prevalence of beta-lactamases. The most common enzymes responsible for resistance to aminopenicillins and older (1st generation) cephalosporins are the TEM-1, TEM-2, OXA-1 and SHV-
Autor:
W. Cullmann, Rudolf L. Then
Publikováno v:
Drug Investigation. 3:299-307
Cefetamet pivoxil (pivoxyl) is an orally active cephalosporin in advanced clinical development sharing a 2-aminothiazolyl- and a methoxyimino-moiety as side chains, in common with other third generation cephalosporins. Consequently, cefetamet is high