Zobrazeno 1 - 10
of 1 774
pro vyhledávání: '"W. Conrad"'
Autor:
W. Conrad Liles, Jeremie Joffre
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Externí odkaz:
https://doaj.org/article/31e09dcce6cc47adb1a7e48a35a06a73
Autor:
Yu‐Hua Chow, Cecilia López‐Martínez, W. Conrad Liles, William A. Altemeier, Sina A. Gharib, Chi F. Hung
Publikováno v:
FASEB BioAdvances, Vol 6, Iss 1, Pp 12-25 (2024)
Abstract Variations in the Toll‐interacting protein (TOLLIP) gene have been identified in genome‐wide association studies to correlate with risk of disease, mortality, and response to N‐acetylcysteine therapy in idiopathic pulmonary fibrosis. A
Externí odkaz:
https://doaj.org/article/0781413b03074286b49c5306ce631d9e
Autor:
Mithu De, Gregory Serpa, Eryn Zuiker, Katherine B. Hisert, W. Conrad Liles, Anne M. Manicone, Emily A. Hemann, Matthew E. Long
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 14 (2024)
Chronic pulmonary bacterial infections and associated inflammation remain a cause of morbidity and mortality in people with cystic fibrosis (PwCF) despite new modulator therapies. Therapies targeting host factors that dampen detrimental inflammation
Externí odkaz:
https://doaj.org/article/27d876f7f26041368b9612c3659d7983
Autor:
Runa Kuley, Bhargavi Duvvuri, Jeffrey J. Wallin, Nam Bui, Mary Vic Adona, Nicholas G. O’Connor, Sharon K. Sahi, Ian B. Stanaway, Mark M. Wurfel, Eric D. Morrell, W. Conrad Liles, Pavan K. Bhatraju, Christian Lood
Publikováno v:
Virulence, Vol 14, Iss 1 (2023)
ABSTRACTNeutrophil dysregulation is well established in COVID-19. However, factors contributing to neutrophil activation in COVID-19 are not clear. We assessed if N-formyl methionine (fMet) contributes to neutrophil activation in COVID-19. Elevated l
Externí odkaz:
https://doaj.org/article/68bb341cfe6c496ea2f3d2dd7b86a2b7
Autor:
Yixi Xu, Anusua Trivedi, Nicholas Becker, Marian Blazes, Juan Lavista Ferres, Aaron Lee, W. Conrad Liles, Pavan K. Bhatraju
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract COVID-19 mortality risk stratification tools could improve care, inform accurate and rapid triage decisions, and guide family discussions regarding goals of care. A minority of COVID-19 prognostic tools have been tested in external cohorts.
Externí odkaz:
https://doaj.org/article/40b07ce51df24bc690725b63e7e38abb
Autor:
Neha A. Sathe, MD, MSc, Ana Mostaghim, MD, Elizabeth Barnes, BS, Nicholas G. O’Connor, BS, Sharon K. Sahi, MS, Sana S. Sakr, PhD, Jana M. Zahlan, BS, Craig H. Smith, MD, Michael Fitzpatrick, BS, Eric D. Morrell, MD, W. Conrad Liles, MD, PhD, Pavan K. Bhatraju, MD, MSc
Publikováno v:
Critical Care Explorations, Vol 5, Iss 7, p e0945 (2023)
IMPORTANCE:. Kidney and lung injury are closely inter-related during acute respiratory illness, but the molecular risk factors that these organ injuries share are not well defined. OBJECTIVES:. We identified plasma biomarkers associated with severe a
Externí odkaz:
https://doaj.org/article/4aa7528dc2fe41138a4f33b228f41845
Publikováno v:
Diagnostics, Vol 14, Iss 3, p 300 (2024)
Although the diagnosis of sepsis requires the identification of the three components of infection, a systemic inflammation response, and organ dysfunction, there is currently no consensus on gold-standard criteria. There are however suggested tools a
Externí odkaz:
https://doaj.org/article/e6bc01adf1d04b5a9b797d9433a6d379
Autor:
Anthony Ortiz, Anusua Trivedi, Jocelyn Desbiens, Marian Blazes, Caleb Robinson, Sunil Gupta, Rahul Dodhia, Pavan K. Bhatraju, W. Conrad Liles, Aaron Lee, Juan M. Lavista Ferres
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract The rapid evolution of the novel coronavirus disease (COVID-19) pandemic has resulted in an urgent need for effective clinical tools to reduce transmission and manage severe illness. Numerous teams are quickly developing artificial intellige
Externí odkaz:
https://doaj.org/article/cad5bf2a3e1d438ab7b643c5e75c7601
Autor:
Jérémie Joffre, W. Conrad Liles
Publikováno v:
Frontiers in Medicine, Vol 9 (2023)
Externí odkaz:
https://doaj.org/article/9ecf30d180cf434a82dc1eeea48ec19c
Autor:
Aleksandra Leligdowicz, Andrea L. Conroy, Michael Hawkes, Melissa Richard-Greenblatt, Kathleen Zhong, Robert O. Opoka, Sophie Namasopo, David Bell, W. Conrad Liles, Bruno R. da Costa, Peter Jüni, Kevin C. Kain
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
Identification of febrile children at risk of death in low-resource settings can improve survival, but tools for their prompt recognition are lacking. Here, the authors show that sTREM-1 measured at clinical presentation predicts in-hospital mortalit
Externí odkaz:
https://doaj.org/article/5581a9756f0d416e88763e8d7283bcb5